Home Pharmacognosy Innovation in cancer prevention – biorobots carrying cordyceps extract

Innovation in cancer prevention – biorobots carrying cordyceps extract


Jul 13, 2021

(Nanowerk News) Several studies around the world have confirmed that the cordycepin extracted from cordyceps is a crucial active ingredient that kills cancer cells, but the problem is that the human intestine absorbs very little of this substance.

Dr Teerapong Yata, Senior Lecturer, Biochemistry Unit, Department of Physiology, Faculty of Veterinary Sciences, and Dr Waranyu Pooncharoen, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University collaborated with the Center National Nanotechnology National (NANOTEC) conduct research to answer this question through a delivery system assisted by bio-robots to transport “Cordycepin” to specifically targeted cancer cells.


Extraction of cordyceps cancer inhibitors

Dr Teerapong explained that taking cordyceps or cordyceps extracts, as sold and consumed today, may have benefits in terms of maintaining general health, but almost no effect in terms of inhibition of cancer cells.

“We have to extract the substance. “Cordycepin” and see how it can be delivered to cancerous tissue in the body, as the gut can absorb very little. Therefore, NANOTEC has developed bio-robots called “nanoparticle delivery system” to deliver the extract to the targeted location where we want the extract to be active. ”

Biorobots delivering extracts to treat cancer

The nanotechnology delivery system is an answer to the problem of cancer treatment. By bringing the active substance to its target and helping the body to better absorb cordycepin, the delivery system also reduces the risk of drug residues and toxicity in the body.

“There is no definitive conclusion as to which substance in cordyceps causes side effects or is toxic to the body, such as stomach, liver, kidneys, so if we have a conductor to encapsulate only substances important and target delivery to destroy cancer cells only, this will help reduce side effects, especially toxic effects on the liver.

Dr Teerapong further explained that the “controlled release” of nanoparticles can reduce potential toxicity affecting the liver or kidneys.

Bio-robot – a medical innovation for targeted treatment

Research on “bio-robots” does not stop there. According to Dr. Teerapong, “Currently, the process of ‘active targeting’ is under investigation. It is the use of targeted molecules to deliver important substances to the desired organs as precisely as possible. This is because this innovative robot of the future is not created just to cure cancer, but can also be used to encapsulate a substance and deliver it to the area that needs treatment.

Recently, researchers have started using bio-robots to transport important substances, both drugs and vaccines. Different types of substances require different designs which must be carried out under the guidance of doctors. In addition, today, bio-robots are also used to treat animals, concluded Dr Teerapong.