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The Hamline-Midway Library needs to change, but does it need to be demolished?

Passing through the gates of the Hamline-Midway library remains a special moment for St. Paul resident Bonnie Youngquist, who remembers decades of visiting with her family.

“When you enter the hall, look at the facade above the door: it has an interesting and significant feature,” says Youngquist, who has collected more than 1,500 signatures on a petition to save the library building. “The Hamline-Midway Library was my favorite. My kids practically grew up in this library, [watching] the Bill the juggler shows. We know it well.

Over the past year, competing groups of library advocates have fought a quiet battle over the future of the small brick building. Advocates like Youngquist have been write letters to the editor and launching petitions, while other library supporters push forward a plan to replace the building with a larger, newer one. Earlier this month, the city Investment and Budget Committee heard testimonials about the importance of investing in the library. But at this point, with no firm plans officially on the books, it’s not clear whether to demolish the 90-year-old building.

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One point of agreement: it is outdated

Everyone agrees that the quaint building on Minnehaha Avenue, just off a bustling corner of Snelling, may need reinvestment. Compared to the newer and larger libraries in the city, like the Rondo branch located 3 km to the east, the facility looks distinctly outdated. The 1930 building can be described as awesome and has been doing Yeoman’s job for 90 years.

Hence the need for change, as recently testified by members of the community before the committee appointed by the mayor of the city.

“I visited the Hamline-Midway branch, volunteered there, raised kids there and saw how many facilities are used in various ways,” said Deepa Rathnam Nirmal, who spoke during the public testimony before the city’s CIB committee. Nirmal is one of the members of the Hamline Midway Library Association, who have been organizing for years to improve their local branch.

“It’s very well liked [but] shows a lot of wear, [and] it just doesn’t meet the needs of the growing community, ”Nirmal said. “I think we would do well to have a brand new building just because of the constraints. I’m sure we can incorporate some of the charm of the existing building.

The CIB committee is considering whether to grant just over $ 8 million to this library as part of a competitive process that pits projects against others in the city. But because Requirement does not specify what exactly will happen to the building, the Hamline-Midway situation is as vague as anything in local politics.

A quirky story

Uncertainty is not new to Hamline-Midway Library patrons. Like many of the city’s smaller branches, it has been on the verge of a library budget pit for years. In 2009, faced with a shortfall of $ 2.1 million, then-mayor Chris Coleman offered to close the library for good. In response, neighbors pushed back and organized, keeping the branch open.

In fact, the Hamline-Midway branch has had a special connection to community activism since its inception. The only reason it exists today is because neighbors organized during the 1918 flu pandemic to acquire land for the building. One hundred years and a pandemic later, history is repeating itself.

“The story behind the scenes is quite interesting,” Youngquist said. “During the Spanish flu, neighbors raised funds and donated money to buy land for a library building. And much later, during the Depression, the library was built after a protracted trial to access the funds of William Hale’s estate.

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As Youngquist describes it, the library’s strange provenance has its roots in a little-known East Coast graft named Henry hale (Nathan Hale’s grandson). Hale was a renowned judge and chairman of the library board, and left a provision in his will to build one in St. Paul. Although he died in 1890, the bequest stagnated for decades as his wife and descendants retained control of the estate. The standoff only ended when a group of Hamline-Midway library advocates filed a lawsuit to force construction of the library branch.

Courtesy of the Minnesota Historical Society

An image of the Hamline-Midway Library dedication in 1930.

Completed in 1930 at the start of the Depression, the building lacks the ornamentation of other historic libraries in the city. Yet the building is stately, with windows that resemble an English estate. Above the entrance, an inscription is carved in stone under a frieze of an open book carrying a torch.

As you walk into the doorway, the bookcase appears to be a ringer for the handful of old Carnegie bookcases in town, roughly the same size and design, minus a few decorative flourishes like ceiling moldings. . I imagine if you told most customers it was the same at St. Anthony or Riverview branches, they would believe you.

These libraries have been variously enlarged, restored or sold, but each remains a historical landmark in their respective neighborhoods. For example, when the SPPL built a new East Side Library to replace the long-suffering Carnegie Library on Greenbrier Street, they found a new site a few blocks away and sold the old building. Today the old building houses the East Side Freedom Library, a non-profit organization that has reused the building in a wonderful way.

Some library advocates are considering a similar fate for the Henry Hale building, offering different options that would move a new facility somewhere nearby.


From a librarian’s perspective, there is a long list of flaws with the existing structure, ranging from HVAC issues to ADA accessibility to space requirements. By reading the existing documents, the building boundaries seem to be more of a problem than they are worth, for the library’s long-range plans.

Saint-Paul Public Library

That’s why the Hamline-Midway Library Association, a grassroots group that lobbied to save the facility 12 years ago, issued a statement earlier this year support demolition.

To conclude their position, they write:

We would also work to ensure that we have opportunities as a community to deal with any difficult emotions that would arise from losing our old library and building a new one, and to find ways to respect and integrate the story of the bookcase in a new design.

At this stage, the CIB proposal is not explicit on the future of the building. If the Hamline-Midway branch receives its funding, the designated dollars would be unlimited. Library administrators could either use the dollars to restore or replace the structure, and have not stated their plans explicitly.

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Meanwhile, right next to the Henry Hale building, Lloyds Pharmacy, a two-story wooden building, is currently under reconstruction a year after being set on fire by an arsonist. At the time, community members mourned the loss of the structure and the institution. For many in the Hamline-Midway neighborhood, including myself, it’s heartwarming to see the building rebuilt in place of the burnt-out ruin.

Only time will tell if the Hamline-Midway Library branch, with its bizarre history, can survive the complexities of the city’s funding cycles and institutional negotiations. City leaders will soon be forced to decide whether the building deserves the extra attention and time it would take to preserve the structure to serve another generation.

Missouri Board of Directors Investigates Working Conditions in Pharmacies

ST. LOUIS (AP) – A state council is examining allegations that pharmacists were overworked, forced to adhere to company measures and lacked time to safely fill prescriptions.

St. Louis Post-Expedition reports that the Missouri Board of Pharmacy appoint a task force this month to examine working conditions at state pharmacies after hundreds of pharmacists raised concerns.

“I’ve heard pharmacists say they don’t drink anything before they leave because they’re worried they won’t be able to go to the bathroom,” said Ron Fitzwater, CEO of the Missouri Pharmacy Association. “It’s not even healthy, let alone good business practice.”

The board of directors said in a statement earlier this year that “patient safety should not be compromised for company profits.”

Pharmacy giants CVS Health and Walgreens both told Post-Dispatch they are committed to treating patients. Walmart did not respond to a request for comment.

Kimberly Grinston, executive director of the Missouri Board of Pharmacy, said COVID-19 has placed additional requirements on pharmacists. Some have had to deal with staff absences due to quarantine or illness. And the vaccines were rolled out in the winter, which is already a busy time.

“We had a convergence of all of these things, so the board had concerns about staffing and working conditions,” Grinston said.

American Chemical Society Journals Remain Most Cited in Chemistry

American Chemical Society (ACS) journals reached new levels of impact, citations, and results in 2020. The 2021 Web of Science â„¢ Journal Citation ReportsClarivate â„¢, released yesterday, details how ACS journals are influencing and shaping chemistry in its many fields.

Across their portfolio, ACS journals achieved a median Journal Impact Factor â„¢ in 2020, Journal Citation Reportsâ„¢ (Clarivate, 2021), 5.097, a 14% increase from 2019. An Impact Factor â„¢ Journal, calculated annually by Clarivate, provides a measure of how often an average journal article was cited in the previous year. This increase demonstrates that articles published in ACS journals are increasingly relevant to scientists. The total number of citations also increased by over 550,000, an increase of over 15%, and citations increased from the previous year for each of ACS’s journals.

ACS journals have been steadily reaching new heights of excellence for over a decade, and this year’s numbers represent the highest in publisher history. The number of articles published also increased, to 58,974 articles, and usage among ACS readers skyrocketed, with nearly 170 million article downloads in the journal portfolio. As a result, ACS journals were named most cited or featured in 10 categories, including five of the seven major chemistry categories: Chemistry, Analytical; Chemistry, inorganic and nuclear; Chemistry, Medicinal; Chemistry, Multidisciplinary; and Chemistry, Organic. The importance of ACS in the chemicals portfolio far exceeds its competitors, such as Wiley, Elsevier, Springer Nature or Taylor & Francis, whose portfolios have not reached the same level of importance in the categories of the chemistry.

“To see strong growth in production and citations in such a difficult year is a testament to the dedication of our authors, editors and peer reviewers and the trust they place in our journals,” said Sarah Tegen, Ph. D., senior vice president. , AEC Publications Division. “Even as laboratories and universities closed and researchers around the world adapted to new ways of working, we came together as a community to ensure that the dissemination of scientific papers did not stop. The growth of our portfolio is a triumph over a historic year of obstacles, and we are deeply grateful to those who made this possible. “

the Journal of the American Chemical Society (JACS), ACS’s flagship journal, remains the most cited chemistry journal with 609,263 citations in total and an Impact Factor â„¢ Journal of 15,419. This solid performance consolidates its place above competing journals, such as Wiley’s Angewandte Chemie International Edition. JACS articles were downloaded over 26 million times in 2020. Chemical notices remains the journal with the greatest impact in the Chemistry category, multidisciplinary, with an Impact Factor â„¢ Journal of 60,622, more than 220,000 citations and more than 6.3 million downloads.

Reflecting their influence and impact across all fields of chemistry, many ACS thematic journals received their highest ever Impact Factor â„¢ Journal and record number of citations in 2020. ACS Nano received an Impact Factor â„¢ Journal of 15,881 and recorded nearly 200,000 citations and over 8 million downloads. Chemical research accounts obtained a Journal Impact Factor â„¢ of 22,384. the Journal of Agricultural and Food Chemistry was again the most cited journal in the Agriculture category, multidisciplinary with a total of 144,020 citations. With 156,738 citations, Analytical Chemistry was again the most cited journal in the Chemistry, Analytics category. Inorganic chemistry once again topped the Chemistry, Inorganic and Nuclear category with 103,059 citations, and the Journal of Medicinal Chemistry remained the most cited journal in the Chemistry, Medicinal category with 85,946 citations. Crystal growth and conception remained the most cited journal in the Crystallography category with 33,973 citations, and Macromolecules maintained its position as the most cited journal in the Polymer Science category with 111,371 citations. Environmental sciences and technologies remained the most cited journal in the Engineering, Environmental Sciences and Environmental Sciences categories, with a record 217,954 citations, beating competing journals.

ACS’s open access journals have continued to grow in importance. Created in 2015, ACS Central Science, ACS’s first open access journal, achieved a Journal Impact Factor â„¢ of 14,553 with over 11,000 citations and over 2 million article downloads. ACS OmegaThe Journal Impact Factor â„¢ grew to 3,512, and the open access journal had over 23,000 citations, more than double the previous year, with its Journal Impact Factor â„¢ surpassing its closest competitor, RSC Advances. ACS recently expanded its portfolio of open access journals, introducing JACS Au in 2020 and the ACS Au journal suite in 2021. The significant growth of its existing open access portfolio is a promising development as ACS evolves to meet the needs of the growing community of authors who want or need to publish in open access journals. .

To support further research on applied materials, ACS has expanded its portfolio of journals in this area, and several of these journals have received their first Impact Factor â„¢ Journal. Applied materials and interfaces ACS has maintained its prominence in the field, with an Impact Factor â„¢ Journal of 9,229 and 274,703 citations. Journal articles were downloaded more than 10.4 million times in 2020. ACS Applied Energetic Materials nearly tripled its total citations, ending the year with 12,740. Applied electronic materials ACS received a partial Journal Impact Factor â„¢ of 3.314, ACS Applied Polymer Materials received a partial Journal Impact Factor â„¢ of 4,089, and Applied nanomaterials ACS obtained a First Journal Impact Factor â„¢ of 5.097. In our wider material portfolio, ACS Material Letters debuted with a partial Impact Factor â„¢ Journal of 8.312, demonstrating how quickly the journal has grown in importance in its community. The strong performance of these journals secures ACS’s position as the first place for materials researchers to publish their work.

This year Journal Citation Reportsâ„¢ has also recorded significant gains in many ACS journals launched over the past decade. ACS catalysis, created in 2011, received an Impact Factor â„¢ Journal of 13,084 and over 92,000 citations. ACS macro letters, established in 2012, obtained a Journal Impact Factor â„¢ of 6,903 with 13,599 citations, while ACS Sustainable Chemistry and Engineering, created in 2013, received an Impact Factor â„¢ Journal of 8,198 and 62,273 citations, an increase of over 50% over the previous year. ACS Energy Letters, created in 2016, saw its Journal Impact Factor â„¢ increase to 23.101.

“The events of 2020 have made it even clearer the critical importance of scientific research to society,” said James Milne, Ph.D., president of the publications division of the ACS. “The growing global influence of all of our journals has not only strengthened ACS ‘reputation as the premier publishing venue in chemistry, but also demonstrated how we have fulfilled our own mission of advancing the chemistry business for profit. of the Earth and all of its inhabitants. . “

/ Public distribution. This material is from the original organization and may be ad hoc in nature, edited for clarity, style and length. See it in full here.

Police: New York trio – with illegal gun

PLYMOUTH – A gun with an erased serial number was seized during the arrest of three New Yorkers who police say were involved in illegal prescription fraud at a local pharmacy.

Agents were dispatched to CVS Pharmacy with a prescription fraud complaint around 5 p.m. Tuesday.

Police said officers set up surveillance and saw the individual enter the store, attempting to obtain codeine syrup using a fake prescription, police said. Officers also identified two other people involved, who police said were waiting in the parking lot.

The other two were arrested and police found a prescription bottle of codeine and a .45 caliber firearm with the serial number erased, police said.

“Codeine is an opioid and has a high potential for abuse,” police said. “This arrest demonstrates the continued commitment of the Plymouth Police Department in the fight against opioid addiction. “

Antwain Jones, 19, of Bronx, NY, has been charged with illegally obtaining drugs by way of a fraudulent prescription, possession of a controlled substance, no pistol license, weapon in a motor vehicle, modified serial number and possession of a stolen firearm. He was being held on $ 25,000 bail.

The other two, Simone Jones, also 25 from the Bronx and Shemar Webster, 19, from Brooklyn, NY, have been charged with illegally obtaining drugs through a fraudulent prescription and possession of a substance. controlled. They were each held on $ 10,000 bond.

To find out what resources are available for those struggling with opioid or heroin addiction, call 800-563-4086.

Lyme disease; the great impersonator wrongly diagnosed as arthritis

The cure for Lyme disease by Dr Cass Ingram

Author The Cure of Lyme Disease

Dr Cass Ingram

tick bite head comes in first

Example of tick bite

Dr. Cass Ingram educates readers and listeners about Lyme disease and how difficult it is to diagnose as it mimics arthritis, joint pain, and other health issues.

Lyme disease actually invades the deepest recesses of the joint. Subsequently, it appears to selectively hide in the joint capsule, where it causes significant inflammation as well as tissue destruction.

– Dr Cass Ingram

BUFFALO GROVE, IL, USA, July 1, 2021 /EINPresswire.com/ – Lyme disease cases are on the rise as summer, also known as tick season, shifts into high gear. Lyme disease is potentially fatal, and the CDC estimates the annual number of cases at half a million. Dr Cass Ingram, nutritionist and author of The Lyme Disease Cure, warns people that this number is considered low because many cases are hidden and misdiagnosed. Difficulties in diagnosis arise from the fact that Lyme disease is the great imitator; mimicking arthritis, rheumatoid arthritis, MS and other health problems.

There are several types of potentially fatal ticks, including blacklegged deer tick, star tick, wood tick, and others. These ticks inject unusually destructive types of bacteria called “spirochetes” into the human body.

Ticks are barely visible to the naked eye, and in previous years they were only found in the northeastern states. Now, according to the CDC, they are found in most states in the United States.

One of the difficulties in diagnosing the disease is that people don’t know they’ve been bitten or don’t see the common red target rings around a bite, so they don’t alert their doctor to the bite. possibility of Lyme disease. If they have joint pain or joint swelling, it is most often diagnosed as arthritis.

“Lyme disease actually invades the deepest recesses of the joint. Subsequently, it appears to selectively hide in the joint capsule, where it causes significant inflammation as well as tissue destruction. In addition, by a mechanism yet to be determined, it causes damage similar to that of rheumatoid arthritis. Plus, Lyme arthritis is almost as stubborn as the standard type of rheumatoid arthritis, being resistant to most medical treatments, ”says Dr. Ingram, himself a Lyme disease survivor.

“Fortunately, there is hope. This hope comes from the wilderness. Incredibly, there is a wide range of natural complexes that can erase such germs, ”says Dr. Ingram.

“Gray squirrels can carry ticks. Dogs and cats can also carry and bring them home. “

Anyone who is concerned that arthritis or joint pain is Lyme disease can ask their doctor for a test to make sure they are getting an accurate diagnosis. For more information, order The Lyme Disease Cure or visit Dr. Cass Ingram at www.cassingram.com.

About the author Dr Cass Ingram

Dr Cass Ingram, a Lyme disease survivor, is a medical nutritionist who received a BS in Biology and Chemistry from the University of Iowa (1979) and an OD from the University of Osteopathic Medicine and Sciences of Health in Des Moines, IA (1984). He is one of North America’s leading experts on the health benefits and anti-disease properties of wild medicinal spice extracts. Author of over 20 books on natural healing, including The Lyme Disease Cure, he has given answers and hope to millions of people through his lectures and interviews on radio and television programs across the America.

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People are divided over what is being said in a bizarre audio illusion

If you’ve already donated to a cause but are concerned that your contribution may not really be enough to bring about real change, you are not alone. As a single person, it can be difficult to feel like you are having a
real difference, especially if you don’t have much to donate or times are tough (i.e. there’s a global pandemic going on.)

That’s why, for years, the idea of ​​philanthropy looked a bit like a rich man’s thing: if you had millions, you could donate and make a difference. The rest of us were just throwing pennies in a cup and not really doing much.

But it’s a problem: the priorities of the wealthy few do not represent the priorities of many, which means that good causes are often underfunded, leading to a lack of meaningful action.

The thing is, it doesn’t have to be like that. We can
all make a difference, especially if we pool our money.

Enter: Donation circles. It’s when groups of people with common values ​​come together to drive change. They do this by pooling their time and money, then deciding in a circle where it should go. That way, they can bring about real, focused change to one place quickly in a highly motivated way by people giving what they can, be it volunteer hours, money, or a mix of the two. Best of all, giving circles are a social experience – you work together as a community to make sure you do the most good you can.

In other words, giving circles is a way of democratize philanthropy, which makes it more accessible regardless of your age, income, gender or race.

That’s why this year, The Elevate Prize, a non-profit organization founded in 2019, is launching a
new “Giving Circle” pop-up program so that problem solvers, budding philanthropists, and all who want to do good can come together and make real impact on a large scale. And you can do it all in just 90 minutes.

All you have to do is join one of the Elevate Donation Circles online. Find out about organizations that do good for the world, then collect your money and, as a group, direct it to where you think this donation could make the most difference.

But that’s not all: Every donation made is matched by the Elevate Prize Foundation, essentially ensuring that you double your impact for good. The undergraduate theme is education, and Elevate Giving will match up to $ 75,000 in total donations for each cycle.

Ready to get involved?
Elevate Giving experiences start June 26, so register now to make a difference. There is also no minimum fee to join – so get involved no matter what you have to donate. It is philanthropy for all.

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What you bought after receiving the Covid vaccine

The 15 minutes after receiving a Covid vaccine can be a time of deep emotion, a time of relief or gratitude or release while you wait to make sure you don’t have a bad reaction to the vaccine.

So we were curious: if you got vaccinated in a pharmacy, did you walk the aisles while you waited, and if so, did you treat yourself to something impulsive or important or out of character?

We recently asked readers what they were up to. We have received hundreds of responses. You’ve told us stories of celebration, practicality, and the occasional incident – and we asked our photographer Kyle Berger to reimagine some of those stories. Here are a few with your answers, edited and condensed for clarity.

What items did you purchase during your observation period? I bought a box of Penn tennis balls and a pack of four High Noon hard sodas. I then moved from the pharmacy to the tennis courts to meet a friend who was also vaccinated that day. We played a drenched match with sore arms, where we were both incredibly dizzy and our mouths dry. The next day was brutal.

Why did you buy these items? Celebration! We were excited to get out into the world and be active together after receiving the vaccine. We probably should have waited a few days for the side effects to go away.

– Thea Traff, Los Angeles

What items did you purchase during your observation period? To get around that question, I didn’t buy anything for myself at the time, but bought a big pile of gourmet candy bars for the staff giving shots. I tied the pile in a large Aqua ribbon and gave it to the man who administered my shot. I asked him to share it with the others.

Why did you buy these items? Everyone who works to immunize our community is heroes. I am grateful for what they do and what they support!

– Kari Nelsestuen, Portland, Ore.

What items did you purchase during your observation period? Since the confinement, I have become a chocolate addict. It started innocently. While waiting for my 15th birthday, I came across a Russell Stover screen. I tore the cellophane from the incredible bunches of peanuts. I didn’t feel any guilt walking through the box. As I paid for my half-eaten dinner, the cashier gave me tissues to clean the chocolate stains from my lips and fingers. Thanks Moderna.

Why did you buy these items? Oh, I celebrated. I have never bought prepandemic chocolate.

– Kevin Larkin, Los Angeles

What items did you purchase during your observation period? Reese’s Peanut Butter Cups and Old Fashioned Hair Curlers!

Why did you buy these items? Totally festive. I RARELY eat a cup of peanut butter, and because I have crazy long Covid hair, I wanted to spice it up.

– Gab Carbone, Lambertville, NJ

What items did you purchase during your observation period? Drakkar Noir perfume.

Why did you buy these items? I have no idea why I bought it – probably something oblivious to being able to smell things without a mask. What’s hilarious is that I haven’t worn this scent since 2002, and it smells like a teenage version of me going to the club for the first time.

– YV, Miami, Florida.

What items did you purchase during your observation period? Special organic greenie treats and bones for my dogs and a soon-to-be-missed bag of Lay’s Classic crisps that I ate in the car in the parking lot. The dogs seemed pleasantly surprised – although one of them ended up throwing up a bright green puddle on my mom’s new carpet soon after due to the unfamiliar snacks and a sneaky meal in the compost heap.

Why did you buy these items? I felt very emotional and grateful, and wanted to spread joy to my furry loved ones.

– Ariana Lewis, Atlanta

What items did you purchase during your observation period? A 1963 diecast Volkswagen Bus toy by Welly (blue with peace, love and flower decals).

Why did you buy these items? During the pandemic, when the walls in our house seemed to close, I had a long-held fantasy of buying an old VW pickup truck, loading up my two little daughters and hitting the road for weeks, maybe months (an extended version of the real summer road trips I took with my mom and brother as a kid). As I stood in line for my first shot in a CVS, I found myself standing next to a display of Welly vehicles – and only one of the dozen on the shelves was a VW bus. I took it as a sign of some sort – not so much that I should, in fact, buy an old pickup truck, but that our world would soon be opening up again.

– Diane McKay, Dobbs Ferry, NY

What items did you purchase during your observation period? Bota Brick Boxed Wine ($ 9.99 on sale!), Matchbox toy truck for my 2 year old, three different types of hand lotion, bandages.

Why did you buy these items? Boxed wine for the party (also because it was on sale). The hand lotion because my poor hand skin is tired of washing, the bandages because they were right there, and the toy truck for fun.

– Jennie Eldon, Corvallis, Ore.

Ceramic Metering Pump Market 2021 | Covid19 impact assessment


Ceramic Metering Pump Market: Key Insights

Latest research report, entitled “Global Ceramic Metering Pumps Market Insights 2021 and Forecast 2027, this includes an overview and in-depth study of the factors that are considered to have a greater influence on the future development of the market, such as Market size, market share, different industry dynamics, Ceramic Metering Pump market companies, regional analysis of domestic markets, value chain analysis, consumption, demand, key application areas and more. The study also talks about crucial pockets of the industry such as products or services offered, downstream areas, end customers, historical data regarding revenue and sales, market background etc.

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Breakdown data by type: Hydraulic diaphragm type Electromagnetic diaphragm type Mechanical piston type Ceramic metering pump Breakdown data by application: Pharmaceuticals Liquid foods Cosmetics Others Ceramic dosing pump

Global Ceramic Metering Pumps Market By Geography:

• Asia Pacific (Vietnam, China, Malaysia, Japan, Philippines, Korea, Thailand, India, Indonesia and Australia) • Europe (Turkey, Germany, Russia United Kingdom, Italy, France, etc.) • North America (United States, Mexico and Canada.) • South America (Brazil, etc.) • The Middle East and Africa (GCC countries and Egypt.)

Years taken into account to estimate the market size:Year of history: 2015-2021Year of reference : 2021Estimated year: 2021Forecast year: 2021-2027

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How mobile health apps are beneficial

Smartphones, wearable devices and mobile apps have largely dominated the world over the past decades.

FREMONT, California: Mobile health applications offer exciting possibilities for improving medical services. For example, some applications are designed to facilitate remote monitoring of patients to reduce hospitalizations while maintaining physician-patient communication. Other applications allow users to manage and share their health information with health care providers, pharmacies and insurance companies. Moreover, with the massive amounts of health data available today, we need new methods to collect it and convert it into useful information. No tool is more capable of doing this than a mobile device and health apps.

Below are some benefits of the mobile health app.

Better data collection with mobile health apps

Mobile health applications, especially those offering electronic health records via smart wearable health devices, allow faster and easier access to patient health data. Doctors can collect and retrieve clinical data with just one click. This allows more full, informed and timely medical decisions. Patients can also access, organize and store their medical records for better personal care. Even mobile apps allow for earlier detection of chronic diseases like glaucoma, irregular breathing patterns, heart disease or even mental health issues. By collecting data and detecting changes in conditions before they become serious, mobile health apps help improve overall well-being.

Reduce preventable medical errors

Healthcare professionals need access to many types of clinical resources to make accurate diagnostic decisions. For example, doctors and nurses can access medical and pharmaceutical databases and lab results in minutes using mobile health apps. They can also use mobile devices and apps for medication reference guides, medical calculators, clinical guidelines, and other decision support tools. These can make a real difference in disease diagnosis and treatment decisions. Informed medical decisions reduce error rates and improve efficiency and knowledge of the practice. In addition, they can receive an early warning to detect complications and plan the treatment accordingly on the patient’s side.

Improve patient-doctor communication

Communication has always been a complex health problem. Healthcare professionals need to establish clear, precise, and timely interactions with their patients to provide quality patient care and reduce medical abuse. Mobile health apps can bridge the communication gap by offering variable tools to keep communication channels between patients and physicians open 24/7. In other words, patient-physician communication applications provide more efficient medical workflow by keeping physicians remote and effortlessly connected to patients. For example, through secure text messaging or video calling, patients can schedule doctor’s appointments, communicate with caregivers, or even order pharmaceutical prescriptions and have them delivered straight to their cell phones at their homes. Patients can now play a more active and better informed role in health management. Doctors can provide medical advice through virtual consultations from around the world. Specifically, mobile health apps allow doctors to monitor patients after surgery, facilitate faster discharge and virtual follow-up to increase postoperative recovery, improve patient satisfaction.

See also: Best Plastic Technology Solutions Companies

Venatorx Pharmaceuticals Appoints Mary Beth Dorr, Ph.D. Vice President, Clinical Sciences

MALVERN, Pa .– (COMMERCIAL THREAD) – Venatorx Pharmaceuticals announced today that Mary Beth Dorr, Ph.D. has joined the Company as Vice President, Clinical Sciences. With over 30 years of experience in the pharmaceutical industry, Dr. Dorr will be responsible for planning and executing the clinical development of Venatorx’s entire anti-infectives portfolio, including its two antibacterial programs. , cefepime-taniborbactam and ceftibuten / VNRX-7145, as well as its program antiviral, VNRX-9945, a hepatitis B virus inhibitor.

“With three clinical-phase programs and a strong pipeline of discovery, it is vital for us to continue to attract the best and brightest talent to Venatorx,” said Company President and CEO Christopher J. Burns, Ph.D. “Dr. Dorr has dedicated his career to drug development, design and implementation of Phase 1 to 4 clinical trials, primarily for anti-infective products in large and small pharmaceutical companies. We are delighted to have her join our team given her extraordinary track record. ”

Prior to joining Venatorx, Dr Dorr was Product Development Team Leader and Clinical Head of Infectious Diseases at Merck, where his primary responsibility was to lead the clinical development of ZINPLAVA (bezlotoxumab), a monoclonal antibody that binds to and neutralizes It’s hard toxin B. She also led the development teams for DIFICID (fidaxomicin), a macrolide antibiotic for the treatment of It’s hard, and CUBICIN (daptomycin), a lipopeptide antibiotic for severe Gram-positive bacterial infections. Prior to Merck, Dr Dorr was Senior Director of Global Medical Affairs at Wyeth, where she was Program Leader for Phase 4 trials supporting women’s health care and gastrointestinal therapy areas, and served as an advisor in preparation for a pandemic.

In addition to his experience in large pharmaceutical companies, Dr Dorr was the project manager of the development team at Vicuron Pharmaceuticals for dalbavancin, a new intravenous antibiotic for the treatment of severe Gram-positive bacterial infections. Before Vicuron, she held several positions at Rhône-Poulenc Rorer. As Principal Scientist, Dr Dorr was responsible for the clinical pharmacokinetic development of a quinolone antibiotic, ZAGAM (sparfloxacin), and then joined the clinical research group where she led phase 1 and 3 trials for ZAGAM and several phase 3b trials for SYNERCID (quinupristin / dalfopristin), an antibiotic for severe Gram-positive infections. She also worked at Parke-Davis where she was responsible for the design and implementation of preclinical and clinical pharmacokinetic research for several quinolone antibiotics.

“I have a passion for the field of infectious diseases, which has been amplified by the current global COVID-19 pandemic,” said Dr Dorr. “I am excited about the path ahead as Venatorx focuses on the next potential public health crisis of antimicrobial resistance. I look forward to working with my new colleagues to bring the company’s new class of antibiotics and antivirals from “the lab to the bedside”.

Dr Dorr received his Bachelor of Pharmacy from Philadelphia University of Science; his doctorate in pharmacy with a focus on pharmacokinetics and drug metabolism from the University of North Carolina in Chapel Hill, NC, and completed a clinical pharmacy residency at the Veteran’s Administration Hospital in Philadelphia.

About Venatorx Pharmaceuticals, Inc.

Founded in 2010, Venatorx Pharmaceuticals is a private, clinical-stage pharmaceutical company focused on improving health outcomes for patients with multidrug-resistant bacterial infections and difficult-to-treat viral infections. Venatorx has built a world-class internal research and development organization that has filed over 120 patents. The two main clinical stage antibacterial programs of Venatorx are intravenous (cefepime-taniborbactam) and oral (ceftibuten / VNRX-7145) broad-spectrum beta-lactam / beta-lactamase inhibitor combinations which are in phase 3 and phase 1, respectively. In addition, Venatorx is in phase 1 with its first antiviral compound (VNRX-9945), a hepatitis B virus inhibitor. The Company is also developing a new class of non-beta-lactam antibiotics called protein inhibitors. penicillin binding (PBP) that have the potential to bypass more than 70 years of resistance and usher in a new wave of antibacterial therapies. For more information on Venatorx, its partners, investors and pipeline development, please visit www.venatorx.com.

Sustainable Food Center Farmers’ Market Comes Home & More Business Updates From Southwest Austin

The Sustainable Food Center Farmer’s Market has returned to its original location in Sunset Valley, behind the Toney Burger Activity Center. (Courtesy of Texas Farmer’s Market)

1. The Sustainable Food Center Farmer’s Market returned to its original location in Sunset Valley behind the Toney Burger Activity Center, 3200 Jones Road, Austin on June 5th. The Saturday market had moved downtown in 2020, then moved early to Sunset Valley Elementary School. in 2021 as Austin Public Health used the Toney Burger Center as a COVID-19 vaccination site. APH stopped using the center as a drive-thru vaccination site in mid-May. 512-236-0074. www.sustainablefoodcenter.org

2. Ascension Rx hosted a groundbreaking ceremony on June 15 for its new Pharmacy Service Center located in the MetCenter Business Park at 7701-7713 Metropolis Drive, Austin. Ascension Rx, launched in 2020, is the pharmacy arm of the Ascension Seton healthcare provider network. The new $ 8 million, 30,000 square foot facility will serve as a distribution center, specialty pharmacy and hub connecting Ascension’s pharmaceutical sites across the country. www.healthcare.ascension.org

3. OfficeComputer.com has opened a new location at 5725 W. Hwy. 290, Austin, early June. Owner Darren Simon started the tech support and consulting business in 1999, working from his home in the Oak Hill neighborhood until he moved into an office near MoPac in 2014. The company will retain a space of office in downtown while making this return to the Oak Hill area. to get the technicians in the field to customers as quickly as possible, Simon said. www.officecomputer.com

From health care transparency to a public option, lawmakers largely drilled into non-pandemic health care issues in 2021 session

When lawmakers kicked off their 120-day legislative session in February, the state was still recovering from a brutal winter surge of COVID-19, which saw a thousand new cases of the virus reported across the state each day.

Lawmakers early in the session came forward with some modest proposals to address the pandemic — including a bill to give workers paid time off to get vaccinated — but it was unclear at that point what COVID-19’s trajectory in the Silver State would be. With an influx of federal financial support boosting the state’s pandemic response, it wasn’t always easy to tell where lawmakers could be of most help. With sessions slated for only 120 days every other year, it also wasn’t clear they could craft policy responsive enough to the ever-changing needs created by the pandemic.

Instead, lawmakers generally focused on a host of other important, but perhaps less high-profile, health care proposals, from legislation to support the provision of telehealth services in the state, which became all the more popular during the pandemic, to a bill that would provide for Medicaid coverage of community health workers. They also honed in on data transparency, hearing bills that would make changes to the state’s drug pricing transparency program and establish an all-payer claims database in an effort to better understand the health care landscape in the state.

Lawmakers also took up a last-minute bill to establish a state-managed public health insurance option in Nevada, the second-ever to be approved in the nation. Despite reservations from Republican lawmakers — and even from some Democrats — the Legislature introduced and approved the bill in just a little more than a month with some strong-arming by Senate Majority Leader Nicole Cannizzaro (D-Las Vegas), who spearheaded the legislation. 

Behind the scenes, there were frustrations, though, among health care lobbyists. Industry lobbyists, for instance, were caught off guard that Cannizzaro hadn’t involved them in the process of developing the public option bill and dropped the proposal on them in the final weeks of the session.

“I can tell you that when there are very challenging things that occur within health care, when you lock us all in a room, we tend to find solutions,” Tom Clark, lobbyist for the Nevada Association of Health Plans, said during the bill’s first hearing.

Bobbette Bond, policy director for the Culinary Health Fund, also said it was difficult to craft good policy in a legislative environment so heavily shaped by the pandemic. For much of the session, the legislative building was closed to the public and committee meetings were only able to be attended virtually.

“It was hard to get revisions made. It was hard to have good conversations about what could be done. It was hard to build stakeholders,” Bond said. “It was hard to communicate, and I think the policy suffered for that.”

Bond also expressed dismay in the two-thirds requirement for passing tax increases, on the grounds that it has prevented lawmakers from tackling more ambitious health care legislation. Because there isn’t more funding to go around, including to support health care, she said lawmakers have turned to putting mandates on industry.

“The mandates … end up substituting for actual public health policy,” Bond said.

The Culinary Health Fund, which is the health insurance arm of the politically powerful and Democratic-aligned Culinary Union, did, however, continue to play a significant role in shaping health care policy this session with Democrats remaining in control of both chambers of the Legislature. Other industry representatives, who often work collaboratively with Democratic lawmakers but more often align with Republicans on business priorities, had less of an upper hand.

Mike Hillerby, a longtime lobbyist on health care issues in the state, said Nevada loses “a lot of subtlety in the public policy debate” when the discussion is “driven by the relationship between a couple of unions and a couple of hospital chains.”

“That drives so much of what we do, and it’s so contentious. Look at balance billing from 2019. Look at some of the stuff this time, and everything’s driven by that. That’s not indicative of the market and the rest of Nevada. That’s not indicative of what’s happening with providers and patients and payers in rural Nevada, in the Reno area, and yet so much of it is driven by that and that financial reality, that bargaining relationship, those contractual relationships,” Hillerby said. “We just lose a lot of the subtlety and the ability to make better decisions.”

Here’s a look at some of the health policies that passed this session and others that didn’t.

Gov. Steve Sisolak signed several pieces of public health-related legislation into law in Las Vegas on Wednesday, June 9, 2021. (Jeff Scheid/The Nevada Independent)

Public option

The highest-profile piece of health care legislation to pass this year, SB420 — Nevada’s public option bill — was introduced with just a little more than a month left in the legislative session by Cannizzaro, the Senate majority leader. Proponents were quiet about the legislation for the first couple of months of the session until Cannizzaro was asked by a reporter in mid-April about the proposal and health care lobbyists started receiving briefings from consultants on the concept.

The bill, which builds upon previous public option proposals introduced in Nevada in 2017 and 2019, aims to leverage the state’s purchasing power with Medicaid managed care organizations — private insurance companies that contract with the state to provide coverage to the state’s low-income population — to get insurers to also offer public option plans. The plans will resemble existing qualified health plans on the state’s health insurance exchange, though they will be required to be offered at a 5 percent markdown with the goal of reducing the plans’ premium costs by 15 percent over four years. The plans won’t be offered for sale on the exchange until 2026.

The proposal cleared both the Senate and Assembly on party line votes and was signed into law in early June by Gov. Steve Sisolak, making Nevada the second state in the nation after Washington to enact a state-based public health insurance option into law. Colorado became the third state to establish such a policy in mid-June.

Though the legislation was heavily opposed by the health insurance industry — with some groups running ads and sending mailers opposing the proposal — Cannizzaro muscled the bill through the Legislature as the clock counted down to the end of the 120-day session. The bill easily cleared the Senate — where Cannizzaro, as majority leader, controls which bills come to the floor — and Democratic leaders in the Assembly threw their support behind the bill shortly thereafter, setting aside concerns about whether the bill can accomplish its goals of improving health care access and affordability.

“It’s not a secret I have been skeptical of this bill from the very beginning, but I’ve seen the amendments, and I have talked to a number of the different proponents of the bill and opponents of the bill on it,” Assembly Ways and Means Chair Maggie Carlton (D-Las Vegas) said in late May, shortly before allowing the bill to be voted out of her committee. “I feel much more comfortable knowing that, in the future, the people that are in this building now that do come back are well aware of what’s going on, and I trust them to make the best decisions they can to protect the constituents of this state.”

In her remarks, Carlton was referring to the long runway the bill establishes before the public option actually goes into effect, leaving time for the state to conduct an actuarial study to figure out whether the bill actually accomplishes the goals it sets out to and two legislative session in 2023 and 2025 for lawmakers to make any tweaks to the policy as necessary.

Heather Korbulic, who as head of the state’s health insurance exchange will have a key role in shaping the policy’s implementation, has said she plans to bring stakeholders together to “outline the actuarial study and conduct a meaningful analysis of the public option as it relates to every aspect of health care throughout the state.” 

Richard Whitley, director of the Department of Health and Human Services, said in an interview earlier this month that the public option isn’t “a single solution” but “does definitely enhance the opportunity for individuals to gain access to health care.”

“I think of this as an option for coverage,” Whitley said. “It definitely enhances that overall framework of health care coverage.”

Nuclear medicine technologist Vanessa Martinez, views scans at Lou Ruvo Center of Brain Health, on Tuesday, June 11, 2019. (Jeff Scheid/The Nevada Independent)

Transparency and data efforts

For the last two legislative sessions, lawmakers have focused on prescription drug cost transparency, passing a first-in-the-nation diabetes drug transparency law in 2017 and expanding that law to include asthma drugs in 2019. This year, lawmakers built upon those transparency efforts by passing legislation requiring transparency from more portions of the health care industry.

This year, lawmakers approved a bill, SB40, to establish what’s known as an all-payer claims database — a state database of claims of medical, dental and pharmacy services provided in the state. The law requires all public and private insurers regulated under state law to submit their claims to the database and authorizes insurers governed by federal law — such as the Culinary Health Fund — to submit their claims to the database. A similar bill proposed during the 2019 legislative session failed to move forward in the final minutes of that session, though the concept was revived by the Patient Protection Commission, which brought SB40 forward this session.

The bill, however, required extensive work when it got to the Legislature, with state Sen. Julia Ratti (D-Sparks) taking the bill under her wing as chair of the Senate Health and Human Services Committee and working with industry advocates — including the Nevada Association of Health Plans, the Nevada State Medical Association and the Nevada Hospital Association — to finalize the legislation.

“We knew the bill was going to pass, at some level … so we wanted to make sure that the information that was going to be collected was accurate, was consistent with what was required in other states that had all-payer claims databases and also to learn from what those other states had done so we wouldn’t make the same mistakes,” Clark, the Nevada Association of Health Plans lobbyist, said. “Fortunately, Senator Ratti and others were good to work with and we’re comfortable with the way the bill passed.”

The legislation additionally makes data contained in the all-payer claims database confidential, meaning that it is not a public record or subject to subpoena, and specifies how the information contained in it can be disclosed. It can be shared in de-aggregated form to state or federal government entities, including the Nevada System of Higher Education, and any entity that submits data to the database. Anyone else looking to obtain the data can only receive it in aggregated form by submitting a request to the Department of Health and Human Services.

Lawmakers also built upon the diabetes and asthma drug transparency bills passed in 2017 and 2019, respectively, by expanding the universe of drugs the state imposes transparency requirements on. SB380, which was proposed by an interim committee created during the 2019 session to study prescription drug costs, requires the state to compile a list of prescription drugs with a list price that is more than $40 for a course of therapy that has undergone a 10 percent price increase in the preceding year or a 20 percent increase in the two prior years.

The legislation requires drug manufacturers to submit a report to the state explaining the reason for the price increase and explaining the factors that contributed to the price increase. Meanwhile, pharmacy benefit managers, or PBMs, the middlemen in the drug pricing process, are required to submit their own reports with certain data about the drugs, including rebates negotiated with manufacturers and the amount of the rebates retained by the PBM.

The state’s drug transparency program will also, for the first time, have funding behind it, utilizing dollars that have been collected in the form of fines paid by companies for not complying with the state’s drug transparency law. The Department of Health and Human Services put a $780,000 fiscal note on the bill to allow state health officials to transfer the existing drug transparency database to the state’s Enterprise Information Technology Services Division and hire a pharmacist and management analyst to manage the drug transparency program.

SB380 was, however, only one of two bills put forward by the interim prescription drug committee to pass this session. The other was SB396, which allows the state to establish intra- and interstate drug purchasing coalitions with private entities. 

The three bills that did not pass were:

  • SB201, which would have licensed pharmaceutical sales representatives
  • SB378, which would have required at least half of the health plans offered in the state by private insurers to provide prescription drug coverage with no deductible and a fixed copayment and limit the total amount of copayments insured individuals are required to pay in a year 
  • SB392, which would have licensed PBMs and created additional rules for how PBMs can operate.

Nick McGee, senior director of public affairs for PhRMA, the drug industry advocacy organization, in an email expressed disappointment that lawmakers pursued SB380 this session while not advancing the other proposals out of the interim committee. PhRMA did, however, in the end testify in neutral on SB380.

“We are disappointed that the legislature overlooked this opportunity to address patients’ concerns related to their ability to afford and access the medicines they need,” McGee said. “Instead, lawmakers pursued onerous reporting and unnecessary registration requirements that won’t do anything to help patients afford their medicines and fail to provide transparency into why insurers are shifting more and more costs on to patients.”

Bond, the policy director for the Culinary Health Fund, which played a key role in bringing the 2017 bill to fruition, described SB380 as a “step forward,” though she said the bill didn’t end up “as strong as we would have liked.”

“It’s incremental, and it’s progress,” she said.

Lawmakers did not advance SB171, sponsored by state Sen. Joe Hardy (R-Boulder City), which would have barred most insurance companies from implementing copayment accumulator programs for any drug for which there is not a less expensive alternative or generic drug. Such programs prevent drug manufacturer coupons from applying toward patients’ deductibles and maximum out-of-pocket costs.

The Legislature additionally made a budgetary change to boost transparency, approving a request from the Department of Health and Human Services to centralize its data analysis efforts within the office of Data Analytics within the Director’s Office, while the Patient Protection Commission, which is focusing on health care spending and costs, was transferred from the governor’s office to Director’s Office as well.

Whitley, the department’s director, framed the reshuffling as an effort to bring together disparate health data collection and analysis efforts, adding that the pandemic showed the kind of real-time data the department could provide, as in the case of its COVID-19 dashboard, among other dashboards it now maintains.

“Usually people go, ‘We need more money.” Well, in government sometimes what you need is organizational structure,” Whitley said. “Putting data analytics all in one unit in my office … was really because of seeing all of the benefits that were coming out of monitoring the pandemic. That really served to inform what we could be doing.”

The Legislature also made a significant change to the Patient Protection Commission this session, transforming it from a largely industry-focused body to one instead made up largely of non-profit health industry representatives and patient advocates. AB348, sponsored by Carlton, requires the commission be made up of:

  • two patient advocates
  • one for-profit health care provider
  • one registered nurse who practices as a nonprofit hospital
  • one physician or registered nurse who practices at a federally qualified health center 
  • one pharmacist not affiliated with any retail chain pharmacy, or a patient advocate
  • one public nonprofit hospital representative
  • one private nonprofit health insurer representative
  • one member with expertise advocating for the uninsured
  • one member with expertise advocating for people with special health care needs
  • one member who has expertise in health information technology and works with the Department of Health and Human Services
  • one representative of the general public.

The bill also makes the Patient Protection Commission the sole state agency responsible for administering and coordinating the state’s involvement in the Peterson-Milbank Program for Sustainable Health Care Costs, a program that provides technical assistance to states developing targets for statewide health care spending trends. 

Health care industry representatives have, however, chafed at the reduction — or in the case of the drug industry, removal — of their representation on the commission. McGee, from PhRMA, said the change “[undermines] the ability of the commission to provide a comprehensive perspective.”

But Bond, a commission member whose ability to serve will be unaffected by the policy shift, said the change would give patients and consumers more of a voice.

“I understand the concerns about losing representation from the industry, but I also believe that industry has other places where they get represented,” Bond said. “They have the Nevada Hospital Association, the pharmaceutical industry has PhRMA. They get well represented in their core arena. Patients really don’t have a core arena they can go to.”

The Patient Protection Commission’s other bill this session, SB5, also was approved by lawmakers, making a number of changes to telehealth in the state. That bill also contains a data transparency component, requiring the Department of Health and Human Services, to the extent money is available, to establish a data dashboard allowing for the analysis of data relating to telehealth access.

Another big bill that tried to tackle health care costs this session, AB347, sponsored by Assemblyman David Orentlicher (D-Las Vegas), died without receiving a vote. The ambitious bill, among other provisions, proposed establishing a rate-setting commission “to cover reasonable costs of providing health care services” while ensuring providers “earn a fair and reasonable profit.” The bill also would have raised Medicaid payments to Medicare levels via a provider tax.

Northeastern Nevada Regional Hospital staff gather in the emergency room area in Elko
Northeastern Nevada Regional Hospital staff gather in the emergency room area in Elko on Tuesday, April 3, 2018. (Jeff Scheid/The Nevada Independent)

Antitrust in health care

Lawmakers approved two antitrust in health care bills this session. The first one, AB47, requires parties to certain reportable health care or health carrier transactions to submit a notification to the attorney general with information about the transaction at least 30 days before it is finalized. Reportable transactions include material changes to the business or corporate structure of a group practice or health carrier that results in a group practice or health carrier providing 50 percent or more of services within a geographic market.

The bill, which was presented by the attorney general’s office, also prohibits employers from bringing court actions to restrict former employees from providing services to former customers or clients under certain circumstances and bars noncompete agreements from applying to employees that are paid on an hourly wage basis.

The bill attracted opposition from the Nevada Hospital Association and the Nevada State Medical Association. During a May hearing on the bill, Jesse Wadhams, a hospital association lobbyist, thanked the attorney general’s office for working with them on the bill but said the association still could not support the legislation.

“We believe the policy itself comes from a faulty premise,” Wadhams said. “We believe policies should promote more physicians, more access to care and more investment in the health care community.”

Another bill, SB329, requires hospitals to notify the Department of Health and Human Services of any merger, acquisition or similar transaction. It also requires physician group practices to report similar transactions if the practice represents at least 20 percent of the physicians in that specialty in a service area and if the practice represents the largest number of physicians of any practice in the transaction. The legislation, sponsored by state Sen. Roberta Lange (D-Las Vegas) and pushed for by the Culinary Health Fund, requires the department to publish that information online and write an annual report on that information.

Another section of the bill allows the attorney general or other individuals to bring a civil action against a health care provider that “willfully” enters into or solicits a contract that bars insurance companies from steering insured individuals to certain health care providers, putting health care providers in tiers or otherwise restricting insurers. It also makes such an action, known as “anti-tiering” or “anti-steering,” a misdemeanor. (A final amendment to the bill reduced the penalty from a felony to a misdemeanor.)

“I think this is one of the early steps in what will probably be a national trend,” Bond, of the Culinary Health Fund, said in an interview. “I think contract provisions are going to become more and more antitrust looking.”

The bill was opposed by the Nevada Hospital Association and individual Nevada hospital systems and hospitals.

“The technical elements of this and eliminating antitrust provisions by themselves are not the problem we have with this bill — it is making sure that it doesn’t impede the open contracting that occurs otherwise in this highly competitive environment,” Jim Wadhams, a lobbyist for the hospital association, said during a May hearing on the bill.

Tristian McArthur cares for an infant inside the Neonatal Intensive Care Unit at Sunrise Hospital on Tuesday, Dec. 4, 2018. (Daniel Clark/The Nevada Independent)


In perhaps the most substantial victory for health care providers this session, lawmakers rolled back a 6 percent Medicaid rate decrease approved by the Legislature during a budget-slashing special session last summer.

Legislative fiscal analysts projected the move would restore about $300 million in Medicaid funding both in the current fiscal year and in the upcoming biennium, including about $110 million in general fund spending.

“Nevada faced an unprecedented state budget crisis,” Bill Welch, CEO of the Nevada Hospital Association, and Jaron Hildebrand, executive director of the Nevada State Medical Association, wrote in a letter to the governor in May. “The work you did alongside the Nevada Legislature to restore funding to hospitals and providers will be instrumental in safeguarding the health care available to many Nevadans.”

Lawmakers made a number of other changes to Medicaid services as well, providing for coverage of doula services in AB256 and community health workers in AB191. The public option bill, SB420, also contained several Medicaid provisions, including one section providing that pregnant women are considered presumptively eligible for Medicaid without submitting an application for enrollment and another prohibiting pregnant women who are otherwise eligible for Medicaid to be barred from coverage for not having resided in the United States long enough to qualify.

On the mental health front, SB154 requires the state to apply for a waiver to receive federal funding to cover substance use disorder and mental health treatment inside what are known as institutions of mental disease — or psychiatric hospitals or residential treatment facilities with more than 16 beds. Medicaid has long been barred from paying for care in such facilities, but states were recently given the ability to apply to the federal government to cover these services through Medicaid via a federal waiver.

Lawmakers also approved AB358, sponsored by Assembly Speaker Jason Frierson (D-Las Vegas), which will allow for a more seamless transition of incarcerated people to Medicaid upon release from prison. The bill requires a person’s Medicaid eligibility to only be suspended, rather than terminated, when they are incarcerated and specifies that individuals who were not previously on Medicaid should be allowed to apply for enrollment in the program up to six months before their scheduled release date. The bill also requires eligibility for and coverage under Medicaid to be reinstated as soon as possible upon an individual’s release.

In a major victory for families of children with autism, lawmakers passed SB96, which boosts reimbursement rates for autism services.

A member of the Nevada National Guard places a swab in a container after performing a COVID-19 test at the Orleans on Wednesday, May 13, 2020. (Jeff Scheid/The Nevada Independent)

Public health

Lawmakers, by and large, did not spend much time tackling the COVID-19 pandemic head on during their legislative session, likely a byproduct of how rapidly the situation has evolved over the last six months.

Legislators did, however, approve SB209, sponsored by state Sen. Fabian Doñate (D-Las Vegas), which requires employers to provide paid leave to employees to receive the COVID-19 vaccine and requires the Legislative Committee on Health Care to conduct a study during the 2021-2022 interim about the state’s response to the COVID-19 pandemic and make recommendations to the governor and lawmakers for the next legislative session in 2023.

They also passed SB318, also sponsored by Doñate, requiring public health information provided by the state and local health districts to “take reasonable measures” to ensure that people with limited English proficiency have “meaningful and timely access to services to restrain the spread of COVID-19.” 

Beyond COVID, the Legislature passed a number of other public-health related measures this session, including, notably, establishing a public health resource office within the governor’s office through SB424, with the goal of taking a holistic, multidisciplinary approach to public health in the state. 

Lawmakers also approved SB461, which requires the state to disburse $20.9 million of American Rescue Plan dollars to specifically to address needs spotlighted by the public health emergency including “mental health treatment, substance use disorder treatment and other  behavioral health services, construction costs and other capital improvements in public facilities to meet COVID-19-related operational needs and expenses relating to establishing and enhancing public health data systems.”

The Legislature additionally passed a few tobacco-related pieces of legislation including AB59, sponsored by the attorney general’s office, officially raising the tobacco purchase age in the state to 21 — the federal Tobacco 21 law went into effect in December 2019 — and AB360, sponsored by Assemblyman Greg Hafen (R-Pahrump), which prohibits people from selling, distributing or offering to sell cigarettes or other tobacco products to a person under 40 without first conducting age verification. Additionally, SB460, the budget appropriations bill, allocates $5 million for vaping prevention activities.

Lawmakers also approved SB233, sponsored by state Sen. Joe Hardy (R-Boulder City), which appropriates $500,000 to the Nevada Health Services Corps, a state loan repayment program for physicians and other health practitioners aimed at encouraging providers to practice in underserved areas of the state. The Legislature also approved SB379, a health workforce data collection bill that proponents say is critical for the state’s health professional shortage area designation. 

“It’s kind of nerdy, wonky data stuff, but those designations are really critical for Nevada, for loan repayment, for health service corps, for [federally qualified health center] and community health center designation and reimbursement and all sorts of stuff,” said John Packham, co-director of the Nevada Health Workforce Research Center at the University of Nevada, Reno. “We just need better data, period, on the workforce.”

Vitality Unlimited provides substance abuse treatment in Elko
Vitality Unlimited provides substance abuse treatment in Elko. (Jeff Scheid/The Nevada Independent)

Mental health

While mental health advocates have become accustomed to making slim gains each legislative session, Robin Reedy, executive director of NAMI Nevada, believes 2021 was a good session for mental health.

“For once, it’s a long list. It’s just so amazing,” Reedy said of the mental health bills that passed this session. “Everything has just been an uphill climb constantly … but this year, oh my God.”

In addition to SB154, mentioned above, key mental health bills passed this session hone in on mental health parity (AB181), implement the 9-8-8 National Suicide Prevention Hotline (SB390), bolster crisis stabilization services in the state (SB156) and remove stigmatizing language from state law referring to people with mental illness (AB421).

Lawmakers also approved bills put forward by the regional behavioral health policy boards established during the 2017 legislative session, including SB44, which aims to smooth the licensure process to boost the number of behavioral health providers in the state, and SB70, which makes changes to the state’s mental health crisis hold procedures.

Reedy attributed the increased focus on mental health this session to a “perfect storm of things coming together.”

“I think it’s incredibly sad that it took a pandemic for people to actually look more at mental health — when everyone was going through some form of anxiety or depression from being isolated, from not knowing what the future held, from it being just really untenable, and everyone has different levels of acceptance of those things, and living through those things, different levels of resilience,” Reedy said. “Suddenly it’s like, ‘Mental health.’ We’ve been working on this forever. Finally.”

But Reedy said there’s still a long way to go. For instance, she wishes that SB390, which authorizes the state to impose a surcharge on certain mobile communication services, IP-enabled voice services and landline telephone services to fund the 9-8-8 line, would have capped that charge at 50 cents instead of 35 cents. She believes had the session been a regular session and had mental health advocates been able to pack the committee room with patients, they would have been able to get that fee cap increased.

“I just don’t think 35 cents is going to be enough … We’re 51st in the nation [for mental health],” Reedy said. “I know telecommunications does not want to pay to fill the hole, but that means crisis lines are going to be busy.”

A medical staff member prepares a COVID -19 vaccine during the Amazon employees Covid-19 vaccination event at the Amazon Fulfillment Center in North Las Vegas on Wednesday, March 31, 2021. (Jeff Scheid/The Nevada Independent)

Other health care bills

In addition to reigning in drug pricing costs, lawmakers passed several bills making changes to how Nevadans can access certain kinds of prescription drugs. SB190, sponsored by Cannizzaro, will allow pharmacists to dispense certain kinds of hormonal birth control directly to patients. SB325, sponsored by Senate Minority Leader James Settelmeyer (R-Minden), similarly allowed pharmacists to dispense preventative HIV medication, including PrEP.

Other prescription-drug focused bills passed this session include AB178, a bill sponsored by Assemblywoman Melissa Hardy (R-Henderson) requiring insurers to waive restrictions on the time period in which a prescription can be refilled during a state of emergency or disaster declaration, and AB177, a bill from Assemblywoman Teresa Benitez-Thompson (D-Reno) aiming to expand access to prescription drugs in people’s preferred language.

Lawmakers also passed a number of other health care related bills including:

  • SB275, sponsored by state Sen. Dallas Harris (D-Las Vegas), modernizes state laws on HIV by treating the virus the same way as other communicable diseases
  • SB342, sponsored by the Senate Education Committee, puts the legislative stamp of approval on a major partnership between the UNR School of Medicine and Renown Health
  • SB290, sponsored by state Sen. Roberta Lange (D-Las Vegas), makes it easier for certain stage 3 and 4 cancer patients to receive prescription drug treatment by allowing them to apply for an exemption from step therapy, which requires patients to approve that certain drugs are ineffective before insurance will cover a higher-cost drug 
  • SB340, sponsored by state Sen. Dina Neal (D-Las Vegas), provides for the establishment of a home care employment standards board
  • SB251, sponsored by state Sen. Heidi Seevers Gansert (R-Reno), requires primary care providers to conduct or refer patients for screening, genetic counseling and genetic testing in accordance with federal recommendations around BRCA genes, which influence someone’s chance of developing breast cancer

Several health care bills also died with the end of the legislative session, including AB351, which would have allowed terminally ill patients to self-administer life-ending medication, and AB387, a midwife licensure bill.

Richardson June 2021


2021 H E A L T H C A R E E D I T I O N


VOLUME 3, ISSUE 10 JUNE 28JULY 25, 2021

Dip in oce, retail market slows appraisal growth

PROGRAM STATS Enrollment numbers for Richardson ISD’s Healthcare Careers Academy is projected to grow by more than 37% since it was formed in 2019.


Despite a surging housing market, the overall value of taxable property in Richardson is set to see its smallest yearly increase in a decade, according to city ocials. Estimated values released by both Dallas and Col- lin central appraisal districts show Richardson’s prop- erty values growing by just shy of 1% in 2020, revenue CONTINUED ON 18 CHANGE IN TAXABLE VALUE The city’s scal year 2021-22 budget is poised to see its lowest increase in property value growth in a decade, according to appraisal district estimates. This is largely due to a decline in some commercial activity, city ocials said.



770 814

2019-20 2020-21

2021-22 projection



10-year average

Jasiah Sims participates in a pharmacy technician course as part of Richardson ISD’s Healthcare Careers Academy. (Courtesy Richardson ISD)

10% 2% 4% 6% 8% 12% 14%

RISDacademy preps students for health care careers


patient who was bleeding from the carotid artery, Grossman said he remembers feeling shaky even as everything seemed to be going in slow-motion. He recalled watching the other nurses and doctors in the ICU collaborating to save the patient. “It got me [to] realize how beautiful the art of CONTINUED ON 14


When he was a senior in Richardson ISD’s Healthcare Careers Academy, Nathan Grossman helped save a patient’s life during a clinical rota- tion in the intensive care unit at Methodist Rich- ardson Medical Center. After a nurse told him to hold pressure on a




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FROMLEANNE: This month’s edition highlights trends in the local health care market and the growing need for workers in the medical eld. In Richardson, we’re fortunate to have local programs for youth to begin gaining skills to meet the future needs of our community. You’ll also nd a list of area hospitals, urgent care locations and emergency facilities on Page 13. We hope this annual guide is useful for your family, bringing awareness to resources available close to home. Leanne Libby, GENERALMANAGER

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FROMOLIVIA: In Richardson, commercial properties make up 60% of the city’s tax base. This is a good thing for residents because it means a greater share of the property tax burden is shouldered by businesses. But the coronavirus pandemic led to an uptick in commercial vacancies, which has had a negative eect on the city’s overall property valuation. Read more about this trend in a story that begins on our front cover and continues on Page 18. Olivia Lueckemeyer, EDITOR

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Businesses that have recently opened or are coming soon, relocating or expanding

with information on the new location, amenities and member rates is open in front of the future gym. The North Dallas-Richardson location expects to have a children’s club, a free weight center, a cardio center, group exercise classes, personal training, showers and hydromassage beds. 469-399-1720. www.texasfamilytness.com 7 Ace’s Sports Hangar is hoping to hold a soft opening for its new CityLine location at 1250 State St., Ste. 800, Richardson, in early July with a grand opening celebration to follow this sum- mer. In addition to a full bar serving craft cocktails, beer and wine, the eatery will oer menu items such as burgers, wings, catsh, sandwiches and salads. Ace’s Sports Hangar also plans to have regular entertainment ranging from poker nights to live trivia, karaoke and guest DJs. A phone number is not yet available. Find Ace’s Sports Hangar on Facebook. 8 Salad and Go plans to open new locations on Richardson’s western edge in the Spring Creek Village development and on Campbell Road east of US 75 in the coming months. The location at A 14909 N. Coit Road, Dallas, is expected to open later this summer. The location at B 850 E. Campbell Road is slated to open June 28. The drive-thru restaurant oers made-to-order salads, wraps, soups, breakfast burritos and drinks. www.saladandgo.com/dallas 9 Transwestern Development Co. is planning to build The Exchange , a 300,000-square-foot oce building in the CityLine development in Rich- ardson. The six-story Class A oce property is slated to be a joint venture between TDC and BC Station Partners. Construction will commence once a tenant is secured for the building. The Exchange will be located near the southeast corner of the intersection of North Central Expressway and President George Bush Turnpike. 713-270-7700. www.transwesterndevelopment.com RELOCATIONS 10 Centre For Dance relocated to a new facility in Richardson on May 1. The dance studio, which was located just west of Richardson on Campbell Road, is now operating at 2080 N. Collins Blvd.















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COMING SOON 3 Greenville Avenue Pizza Co. , also known as GAPCo, is targeting an early Au- gust opening for its new location at 520 Lockwood Drive, Richardson. The eatery originally hoped to open its Richardson location by the end of 2020, but delays related to construction and the corona- virus pandemic pushed back its opening. GAPCo oers made-from-scratch pizzas with thin, crispy crust and homemade sauce. The business has a Facebook page for its Richardson location where it is providing updates on its progress. 214-826-5404 (Greenville location). www.facebook.com/gapcorichardson 4 Dutch Bros Coee plans to open a drive-thru location by the end of the year at 819 W. Arapaho Drive, Richard- son. A special permit to allow the coee shop near the southwest corner of West Arapaho Road and West Shore Drive was

approved by Richardson City Council in March. The area had been previously zoned for commercial use. With more than 400 locations across 11 states, the Oregon-based drive-thru coee company serves specialty coee, smoothies, freez- es, teas, a private-label Dutch Bros Blue Rebel energy drink and nitrogen-infused cold brew coee. www.dutchbros.com 5 A new Storage 365 facility is sched- uled to open within the next 90 days at 350 Buckingham Road, Richardson. The facility, which will be located near the corner of South Greenville Avenue and Buckingham Road, is expected to have three to ve retail spots underneath the self-storage units that can be leased out by separate businesses. 469-600-8830. www.storage365.us 6 Texas Family Fitness expects to open in mid-July at 1361 W. Campbell Road, Richardson. A preview center


NOWOPEN 1 Forno Pizzeria and Grill opened May 11 at 888 S. Greenville Ave., Ste. 222, Richardson. In addition to a variety of specialty pizzas, the eatery’s menu includes salads, sandwiches, pasta and more. The pizzeria oers delivery or pick- up every day with late-night hours Mon- days through Saturdays. 214-238-6590. www.fornopizzeriagrill.com 2 Sports bar Thirsty Dog opened April 1 at 141 N. Plano Road, Richardson. The establishment oers mixed drinks and specializes in wings and street tacos. The sports bar also oers a nightly happy hour from 4-7 p.m. It opened in the former location of Wae O’licious and is operated by the same company. 469-969-5784. www.thirstydogtx.com

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The business oers a variety of classes for children and adults, including ballet, tap, jazz and hip-hop. Centre For Dance’s new space features six studios and more than 10,000 square feet of space. 972-248-1112. www.centrefordance.com 11 Reverie Bakeshop is in the process of relocating to 980 N. Coit Road, Ste. 2850, Richardson. The bakery oers a variety of vegan cakes and pastries as well as gluten-free options and more. The business closed its former location at 1930 N. Coit Road, Ste. 140, Richardson, in early June. The owners hope to reopen in the new location in late June or early July. 972-238-7511. 12 Music SO Simple marked its fth anniversary in June. The business oers lessons in piano, ute, guitar, voice and violin out of the studio owner Stathia Or- wig opened in 2018 at 1144 Plano Road, Ste. 142, in Richardson’s Arapaho Station development. Music SO Simple initially operated as a home business. Orwig said the business will hold an open house in August to celebrate the anniversary. 469- 778-2121. www.musicsosimple.com www.reveriebakeshop.com ANNIVERSARIES completed an expansion at 7989 Belt Line Road, Ste. 146, Dallas, in June. The business, which is located just outside the western edge of Richardson, is run by husband and wife co-owners Nate Abeyta and Deena Chazoya-Abeyta. Deep Cuts added 2,500 square feet to the shop by expanding into the vacant space next door. “We originally started o with a tiny little lobby and a 4-foot-[wide] meat case,” Abeyta said. “We’ve since expanded that to over 20 feet of meat case and several new cooler options. Everything we were doing, we can do [now] with more capacity to serve more of our guests.” The shop held its grand reopening in the space June 5, which also marked the rst time customers were allowed




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NEWMANAGEMENT 13 Electronics store Gadget Garage reopened under new management in early April at 567 W. Belt Line Road, Ste. 112, Richardson. The store, located in the Richardson Heights Shopping Center, buys, sells and repairs smart- phones, tablets, computers and more. 469-642-4041. www.gadgetgarage.tech IN THE NEWS Fried chicken restaurant Bojangles plans to add 15 locations in the Dallas-Fort Worth Metroplex beginning next year. A representative from the company conrmed one of the rst three, which will be operated by franchisees Sajib Singha and Asish Baidya of SAT Restau- rant Group LLC, will open in Richardson. The other two are slated to be in Garland and Mesquite. The company’s franchise agreement with SAT Restaurant Group outlines the rst locations in Dallas-Fort Worth will open in the rst half of 2022, according to a company press release. An address and phone number for the Rich- ardson location has not been announced. www.bojangles.com inside the business since the start of the coronavirus pandemic. “Customers were really very accommodating to us—we had to pivot our business model overnight,” Abeyta said. “At the same time we were operating via curbside service, we were going through with our renovation.” Deep Cuts carries beef, pork, poultry, sausages, cured meats and cheeses as well as in-house smoked meats, specialty pantry items and more. 469-906-6420. www.deepcutsdallas.com

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July events


their hanger. All materials are provided along with a drink and appetizer from a CityLine restaurant. 6:30-8:30 p.m. $55. CityLine Plaza, 1150 State St., Richardson. 972-739-5080. www.citylinedfw.com 23 THROUGH 25 “BIG FISH, ANEWMUSICAL” Repertory Company Theatre is performing its version of the classic story “Big Fish,” based on the novel by Daniel Wallace and the film directed by Tim Burton. The play tells the story of Edward Bloom and his son, Will, who is determined to discover the truth behind his father’s stories. $28. 7:30 p.m. (Fri.- Sat.). 2 p.m. (Sun.). Repertory Company Theatre, 770 N. Coit Road, Richardson. 972-690-5029. www.rcttheatre.com 25 KIDS PURE SHORES Painting with a Twist in Richardson is hosting a children’s painting class. Parents can join their children for this family friendly event. Group reservations are allowed. Participants can arrive up to 30 minutes before start time. Painting with a Twist is a BYOB studio where attendees can bring food and drinks of their choosing. Guests must be 21 or older to consume alcohol. $30. 1-2:30 p.m. Painting with a Twist, 819 W. Arapaho Road, Richardson. 469-802-6333. www.paintingwithatwist.com/richardson

WORTH THE TRIP JULY 4: ALL AMERICAN 4TH-RED TAIL PAVILION, PLANO Plano’s All American 4th and Fireworks show is launching from Red Tail Pavilion, formerly Oak Point Amphitheater. Parking will be available at Collin College. Plano officials are encouraging those attending to bring blankets, lawn chairs and coolers. The city is asking that pets be left at home, according to the Plano Arts and Events Facebook page. The fireworks show will also stream online. Music will be simulcast on 97.5 KLAK-FM. 6 p.m. Fireworks start at 9:30 p.m. Free. 2801 E. Spring Creek Parkway, Plano. 972-941-7000. More information is available at www.plano.gov/allamerican4th. (Courtesy city of Plano) 09 CITYLINE NIGHT MARKET BY THE BOHO MARKET

JULY 02 THROUGH 4 FREE FEST 2021 Six Springs Tavern is hosting a free, three-day live music event in Richardson. A variety of bands and artists will play 45-minute sets of original music over the course of the event. Six Springs Tavern is typically closed July 4 but chose to stay open this year to hold the music festival, the business said. This event is for all ages. 4 p.m. (doors open). Free. Six Springs Tavern, 147 N. Plano Road, Richardson. 469-917-3040. www.sixspringslive.com

March. Amini discusses a variety of topics on family ties, cultural trappings and social topics with impressions and novel storytelling. Tickets can be purchased online. 8 p.m. $35-$75. Eisemann Center, 2351 Performance Drive, Richardson. 972-744-4650. www.eisemanncenter. com/events-tickets 22 MACRAME PLANT HANGERS WORKSHOP AT CITYLINE The Creative Arts Guild of Wylie is hosting a macrame plant hanger workshop in Richardson. Attendees will learn to tie macrame knots to create bohemian pot hangers. Plants will be potted ahead of time, and participants can choose which plant they want for

CityLine and The Boho Market are partnering to bring more than 25 different local vendor booths to Richardson. This is a nighttime shopping event with live music held at CityLine Plaza. Free parking is available. This is a socially distanced event. 6-10 p.m. Free. CityLine Plaza, 1150 State St., Richardson. 972-739-5080. www.citylinedfw.com 09 MAX AMINI Iranian-American comedian Max Amini is performing a comedy show in the Hill Performance Hall at the Eisemann Center for Performing Arts. This show was originally scheduled to take place in

Find more or submit Richardson events at communityimpact.com/event-calendar. Event organizers can submit local events online to be considered for the print edition. Submitting details for consideration does not guarantee publication.


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Richardson City Council voted June 7 to create a master plan to develop the area around the Arapaho Center Station. (William C. Wadsack/Community Impact Newspaper)

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times. We had diculty making some decisions on the Silver Line project early on,” DART board member Gary Slagel said. “It’s really important to make these things work. You have to have a team that works together. Working with the city of Richardson has been easier than others, from a DART perspective.” Construction on the future Silver Line connection at the existing CityLine station began in May. Lighted arches will connect the two lines together, and the planned Cotton Belt Trail will run between the two sta- tions. Work at the station is expected to last until April 2023, according to DART development plans. The planned UT Dallas station will have a plaza area and act as a “gateway” for the campus and the city, DART ocials said. The station will have a limestone design to match UT Dallas buildings. DART estimates the Silver Line to be completed in 2023. Median work on, near Campbell Road The inside lanes of Campbell Road between Lakeside Boulevard and West Prairie Creek Drive may be closed to trac during median work. A portion of the inside lane of the northbound US 75 frontage road at the intersection may also be closed. The work is part of the third phase of the Campbell Road Auxiliary Lane Project. Timeline: July-late September Cost: privately funded Funding source: Atmos Energy

BY ERICK PIRAYESH The process to redevelop the area around Arapaho Center Station in Richardson is now underway follow- ing a June 7 vote by City Council to begin drafting a master plan. No specics on the renovation were released, but city ocials said the large parking lot across from the Dallas Area Rapid Transit station is a primary focus. During the work session, DART ocials also provided updates on the ongoing construction of a new Silver Line station at The University of Texas at Dallas and a connection at the existing CityLine station. The Silver Line is a 26-mile passenger rail project that will stretch from the Dallas Fort Worth International Airport to Plano. DART ocials told the council during the meeting that the estimated $1.29 billion cost for the Silver Line project had increased to $1.89 billion. “We’ve gone through some tough

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News from Richardson, Richardson ISD & Plano ISD

HIGHLIGHTS RICHARDSON Janet DePuy was elected to serve another term as mayor pro tem following a unanimous vote by City Council on June 21. She will hold the position until the next council election in 2023. RICHARDSON ISD Trustees approved a minimum 2% pay raise for eligible employees June 14 as part of the district’s 2021-22 school year budget. The approximate cost for the raise is just over $6.5 million. PLANO ISD The district will not oer a virtual learning option in the 2021-22 school year, according to an email sent to district families June 8. PISD was developing a permanent virtual school option for students to begin in the fall, provided legislative approval for funding was received. However, the regular session of the Texas Legislature ended May 31 without nal approval of a bill that would have expanded online learning and provided funding for full-time virtual students. Students who have already registered for the planned virtual academy will now resume enrollment at their home campuses, according to the email. Richardson City Council Meets July 12 and 19 at 6 p.m. at City Hall, 411 W. Arapaho Road, Richardson. www.cor.net. The meetings are open to the public and are streamed live on the city’s website. Richardson ISD The board of trustees is on summer break. The next meeting is Aug. 9. www.risd.org Plano ISD The board of trustees is on summer break. The next meeting is Aug. 3. www.pisd.edu MEETINGSWE COVER

Monthlysales tax receiptsupbymore than30%inJune

RISDadministrative space to seeupdates RICHARDSON ISD The board of trustees approved a guaranteed maximum price of just under $1.4 million for planned renovations of the district’s administration building during its June 7 meeting. The work on the 107-year-old building, which is located at 400 S. Greenville Ave., will add oces for district sta, create a exible space for the board of trustees and renovate restrooms, Assistant Superintendent Sandra Hayes said during the meeting. The work will all be done on the sec- ond oor and primarily on the south end of the building, she said. The full budget for the project is $2.55 million, Hayes said. The district plans to pay for the project with money from its local capital projects fund, Hayes said. Chief Financial Ocer David Pate said once the project is paid o, the fund will have approximately $8.3 million left. BY WILLIAM C. WADSACK

BOUNCING BACK Sales tax collections are beginning to improve following an annual loss caused by the pandemic.

$6M $5M $4M $3M $2M $1M $0

2020 2021


RICHARDSON Halfway through 2021, Richardson is slowly recover- ing from a pandemic-driven dip in sales tax revenue seen in 2020. So far this year, Richardson has collected $22.6 million in sales tax, which is up from the $21.3 million recorded at the same time last year, according to data from the state. Percent increases in annual col- lections have been consistent since March, with June allocations rising by more than 30% year-over-year. Collections in Richardson varied during the pandemic. By the end of 2020, Richardson recorded $43.2 million in sales tax revenue, which was about 40% lower than 2019. Assistant City Manager Shanna Plano ISDboard approves budget with $19.6Mdecit PLANO ISD Trustees adopted a budget decit of $19.6 million for the scal year 2021-22 budget during the board’s June 22 meeting. General fund revenue is pro- jected to decrease by just over 1% from the 2020-21 budget to $666.5 million. However, expenditures of $497.4 million and a state recap- ture payment of $187.9 million are expected to lead to the $19.6 BY WILLIAM C. WADSACK

Sims-Bradish said she is cautiously optimistic about Richardson’s performance so far this year. “We continue to budget conser- vatively and will continue to closely watch [sales tax revenue] and other income that provide the resources for the services people depend on every day,” she said. SOURCE: TEXAS COMPTROLLER OF PUBLIC ACCOUNTSCOMMUNITY IMPACT NEWSPAPER million decrease in the district’s balance of operating funds. Recapture redistributes property tax dollars from prop- erty-wealthy districts to those deemed property-poor by the state. The district’s payment into the state’s recapture system for the 2021-22 school year is an $8.1 million increase over last year, according to Chief Financial Ocer Randy McDowell. Adjustments will be made to the FY 2021-22 budget as the year goes on, McDowell said. “We’re optimistic that we’ll be able to bring that $19.6 million [decit] down through … federal [COVID-19 relief] funds,” he said.




The administration building is 107 years old. (Courtesy Richardson ISD)




When it comes to treating stroke, not all neuroscience programs are equal. As a designated Comprehensive Stroke Center, we meet the standards proven to support Better outcomes. So we can help patients recover without missing a beat. Learn more at 469.814.2464 or BSWHealth.com/PlanoNeuro.

Physicians provide clinical services as members of the medical staff at one of Baylor Scott & White Health’s subsidiary, community or affiliated medical centers and do not provide clinical services as employees or agents of those medical centers or Baylor Scott & White Health. Photography may include models or actors and may not represent actual patients. ©2021 Baylor Scott & White Health. 16-ALL-253854 Neurocampaignupdates_LaunchAgency





Baylor Scott & White- Plano is 160-bed acute care hospital and has been serving our neighbors in North Texas since December 2004. We provide adults with personalized care and advanced technology on a beautiful campus. Our hospital has more than 1,000 medical sta members, representing multiple specialties and sub- specialties, including the treatment of brain and spine disorders, scoliosis, cancer, orthopedic conditions, and digestive diseases. We are also designated as a Comprehensive Stroke Center by the Texas Department of State Health Services and DNV-GL.


Methodist Richardson Medical Center is your family’s home for healthcare. Conveniently located at President George Bush Highway and Renner Road, our 269-bed hospital oers quality care to our neighbors in Richardson, Garland, Plano and surrounding areas in Dallas and Collin counties. Our comprehensive quality care oers many specialties and services to meet your needs from primary care to acute care. Our specialties include cardiology, digestive health, neurology and neurosurgery, cancer care, emergency care, orthopedics, robotic surgery, labor and delivery with a level III NICU, and women’s services. Our Campus for Continuing Care also oers behavioral and addiction recovery services, as well as a sleep disorders center, wound care, and physical therapy. Methodist Richardson is proud to be recognized with the gold seal of approval by The Joint Commission for digestive cancer care, as well as shoulders, hip, and knee replacement. Methodist Richardson is here to meet all your family’s needs.





These rankings are updated annually but include data from previous years. There are other factors included that are not listed.

The population of Collin County is slightly more vaccinated than that of Dallas County. Data is accurate as of June 23.





9.19% 14.11% 30.68% 32.15% 8.88% 4.99%

20.21% 6.95% 11.44% 44.77% 10.61% 6.03% 52.53% 2.91% 25.83% 14.95% 3.69% 0%

• LENGTHOF LIFE • QUALITYOF LIFE , such as the number of poor mental and physical health days reported







White Hispanic



• HEALTHBEHAVIORS , such as smoking, obesity, physical activity, excessive drinking, alcohol-impaired driving deaths, sexually transmitted infections and teen births • CLINICAL CARE , including health insurance coverage; number of physicians, dentists and mental health providers; preventable hospital stays; and u vaccinations • SOCIOECONOMIC FACTORS , such as educational attainment levels, children in poverty, income inequality and violent crimes • PHYSICAL ENVIRONMENT FACTORS , such as air pollution, drinking water violations, housing problems and long commutes


36 44 93 36 62 40 123 171

1 1 1 1 1 1


Length of life Overall




Quality of life HEALTH FACTORS



51.85% 1.89% 26.20% 16.00% 4.09% 0%

16-49 12-15* 50-64 80+ 65-79



Health behaviors


Socioeconomic Physical environment Clinical care







*Rankings were not available for 11 of the 243 counties in Texas.





The most dangerous thing you can do in an emergency is to not to treat it like one. Methodist Richardson Medical Center is the clear choice for emergency care. Our emergency department is chest pain accredited and designated as a primary stroke center by the American Heart Association. When an emergency strikes, don’t wait. Your neighbors at Methodist Richardson are here to safely care for you.


Texas law prohibits hospitals from practicing medicine. The physicians on the Methodist Health System medical staff are independent practitioners who are not employees or agents of Methodist Richardson Medical Center, Methodist Health System or any of its affi liated hospitals. Methodist Health System complies with applicable federal civil rights laws and does not discriminate on the basis of race, color, national origin, age, disability, or sex.




Local hospitals, ERs & urgent care clinics

2 0 2 1 H E A L T H C A R E E D I T I O N

5 Children’s Health PM Urgent Care U T F 1291 W. Campbell Road, Ste. 100 9724497677 www.pmpediatrics.com 6 ER Near Me Richardson E T 15767 N. Coit Road, Ste. 100 4695157605 www.ernearmetx.com/locations/richardson 7 Fastercare U T F 4011 E. Renner Road, Ste. 110 9722343299 www.faster-care.com 8 MedStar Family Care/Urgent Care U T F 3017 E. Renner Road, Ste. 100 9724424700 www.medstaruc.com 9 PrimaCare Urgent Care-Richardson T F 1810 N. Plano Road 9726649888 www.pmc.nextcare.com/locations/richardson




COVID19 testing T Hospitals

Urgent care clinic U

Emergency room E Flu vaccines F

COVID19 vaccines V


3 Methodist Richardson Medical Center 2831 E. President George Bush Turnpike 4692041000 www.methodisthealthsystem.org/richardson • Trauma level: N/A • NICU level: III • Total number of employees: 1,400+ • Number of beds: 269 • Telemedicine oerings: Both new and established patients can contact a provider’s oce to determine if a visit can be done virtually. Patients needing non-urgent care can log on to www.methodistnow.life to schedule a virtual visit with a physician or specialist. ERs &Urgent Care 4 CareNow Urgent Care-Richardson U T F 377 W. Campbell Road, Ste. 100 4692322945 www.carenow.com

1 Eminent Medical Center 1351 W. President George Bush Turnpike 4699108800 www.eminentmedicalcenter.com • Trauma level: N/A • NICU level: N/A • Total number of employees: 100 • Number of beds: 7 • Telemedicine oerings: none 2 Methodist Campus for Continuing Care 401 W. Campbell Road 4692041000 www.methodisthealthsystem.org/richardson • Trauma level: N/A • NICU level: N/A • Total number of employees: N/A • Number of beds: 51 • Telemedicine oerings: Established patients can contact a provider’s oce to determine if a visit can be done virtually.

Methodist Richardson Medical Center


10 Sanitas Medical Center U T V F 350 S. Plano Road 2149795420 www.mysanitas.com/en/locations/sanitas- richardson 11 Texas Medical Home U T V F 101 S. Coit Road, Ste. 317 9725258917 www.texasmedicalhome.com

This list is not comprehensive

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CAREER OPPORTUNITIES Regional nonprot InterLink partners with local CTE programs to forecast employment recovery and growth. Below is their list of some of the most in- demand health care jobs in the North Central Region and their salary ranges. Starting pay Experienced pay Job title

saving a life is,” he said. “It was just so eye-opening. It made me realize that I love critical care.” Grossman is now majoring in nursing at Texas A&M University-Corpus Christi, but he credits his time in RISD’s Career and Technical Education, or CTE, courses at JJ Pearce High School with solidifying his desire to become a health care professional. The nearly 1,100 students projected to be part of RISD’s Healthcare Careers Academy in the fall will take dual-credit courses from ninth to 12th grade for the chance to earn up to 16 hours of college credit through the district’s partnershipwithDallas College, CTE Executive Director Sari S. McCoy said. All stu- dents who complete the four-year program receive a Patient Care Technician Level 1 award, she said. They can also earn ve other certications and awards. “Our desire is to equip students with as many tools and as much knowledge and technical skills that are necessary for them to gain employment right away,” McCoy said. “If they continue on to a two-year col- lege or four-year university—or if they just choose to enter the workforce immediately and remain there for a little while—they are fully prepared.” Providingapathway RISD students can take medical terminology, the Level 1 CTE course, at Parkhill Junior High and West- wood Junior High. Those interested in learning more about medicine and jobs related to the eld can then enter the Healthcare Careers Academy at any of the district’s four high schools in ninth grade. Students in ninth and 10th grades take core courses and prerequisites at their home campuses, while 11th and 12th graders split their time between being on campus and taking classes at the Methodist Richard- son Campus for Continuing Care, which is a special- ized hospital that oers limited services. McCoy said they also get hands-on experience at Methodist Rich- ardson, which is a full-service hospital located o the President George Bush Turnpike. Having students trained at Methodist Richard- son is also benecial for the hospital, President Ken Hutchenrider said. Some of the students who have gone through the program have been subsequently hired as employees, he added. “We want to make sure that the students get the absolute best exposure to health care,” Hutchenrider

said. “Anything we can do to bring back our home- grown talent, I think that’s so important.” After high school, local students do not have to travel far to continue their pursuit of a health care education. In addition to the oerings at Dallas Col- lege and Collin College, students can also study nurs- ing at The Chicago School of Professional Psychology campus in Richardson. Another option will be West Coast University, which plans to oer a nursing pro- gram at its Richardson campus opening in August. Interest in the nursing program at The Chicago School has risen since being added last year, espe- cially among students from Richardson, according to Associate Dean Tonya Sawyer-McGee. “[Our Richardson campus] is a great central loca- tion for individuals who live in this area,” she said. Gainingexperience While McCoy said some RISD graduates are able to continue their health care careers as patient tech- nicians right out of high school, there are also many who go to nursing school or enroll in pre-med courses at universities. The district is also speaking with Dallas College about adding pathways for students within the health care academy, McCoy added. After graduating fromRichardson High this spring, Salma Moussaid plans to attend Texas Woman’s University to major in nursing. While she said the hands-on experience she gained from the acad- emy program was initially “terrifying,” it ultimately reinforced her desire to become a pediatric nurse practitioner. “The [academy] had a lot of classes to really pre- pare you,” Moussaid said. “It denitely was worth it and very helpful.” The pursuit of a health care profession is often sparked by an early love of science, according to McDermott Scholar Yilong Peng, who graduated from The University of Texas at Dallas in May. Sometimes that love evolves, as McDermott Scholar Patrick Nnoromele learned as a high school sophomore in Kentucky when his father was diag- nosed with early onset dementia. “During my college career, I set my sights on pur- suing both research and clinical research opportuni- ties,” said Nnoromele, a rising neuroscience senior at UT Dallas. “And I found out that I loved medicine.”


Medical assistants Medical records and health information technicians Licensed practical and licensed vocational nurses









Nursing assistants




Pharmacy technicians




Respiratory therapists Medical clinical laboratory technologists and technicians Radiologic technologists BACHELOR’S DEGREE







Registered nurses


Mental health and substance abuse social workers



Law Offices of Dana D. Huffman, P.C. BERKNER HIGH STEPHEN F. AUSTIN TEXAS WESELYAN LAW 26 YEARS IN PRACTICE ESTATE PLANNING • PROBATE • MEDIATION CIVIL/FAMILY/CPS • ARBITRATION SPRING INTO ACTION WITH ESTATE PLANNING! SOURCES: EMSI, TEXAS WORKFORCE COMMISSION, BUREAU OF LABOR STATISTICS, REGIONAL EMPLOYERS, INTERLINK BOARD AND TASK FORCESCOMMUNITY IMPACT NEWSPAPER Need for health careworkers The coronavirus pandemic disrupted some of the learning opportunities for students in RISD, but it also deteriorated the pipeline of workers joining the health care eld, according to Hutchenrider. Some people decided to move away from direct patient care and nursing after working during the pandemic,


1143 Rockingham, Suite 107, Richardson, TX

972-713-7757 • WWW.HUFFMAN.LAW



2 0 2 1 H E A L T H C A R E E D I T I O N

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PATHWAY FOR HEALTHPROGRAMS Richardson ISD oers a Health Science pathway, in which students can earn college credit, as well as potential health care certications.



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Investigation Healthcare Careers 7TH GRADE


Certications and awards

Dual credit

Medical Terminology (High School Credit) 8TH GRADE

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Anatomy and Physiology

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Project Based Research-Career Cluster Development

Principles of Health Science 9TH GRADE

Combine and get in on the surprise.

Health Science Theory 10TH GRADE

Math for Medical Professionals

CPR rst aid at health care provider level

Medical Microbiology

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State FarmMutual Automobile Insurance Company State Farm Indemnity Company State Farm Fire and Casualty Company State FarmGeneral Insurance Company Bloomington, IL State FarmCounty Mutual Insurance Company of Texas State Farm Lloyds Richardson, TX State Farm Florida Insurance Company Winter Haven, FL 2001865 Stephanie South, Agent 189 N Plano Rd Richardson, TX 75081 Bus: 972-690-0618 [email protected]

Practicum in Health Science I 11TH GRADE

World Health Research


Electrocardiograph technician

caused some existing nurses to suf- fer from burnout or get sick them- selves with COVID-19. Texas faces the second worst nursing short- age in the country and ranks 51st nationally in health care access and aordability, according to a June 9 statement from more than a dozen nursing groups in Texas. “For most of my career, we’ve been in a nursing shortage, unfor- tunately,” said Sawyer-McGee, who is also a nurse practitioner. “We need schools to really get involved in educating the future nurses that we may have.” Britt Berrett, who is director of the bachelor’s degree program in health care management at UT Dallas’ Naveen Jindal School of Management, estimated COVID-19 has delayed the pipeline of future health care workers by 15-18 months. But that gap can be overcome, said Berrett, who has already seen an uptick in nursing students training in hospitals and clinics. “[The pandemic] has actually ele- vated the awareness of the impor- tance of caregivers,” he said. “I’m working with students who want to do good. … I think that this is a cat- alyst for new entry into the health care space.”

Phlebotomy technician

Practicum in Health Science II 12TH GRADE

Pharmacy technician

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Health Professions Readiness

Patient care technician UPON GRADUATION

he said. “By being able to expose people to health care [through] programs that we have set up with [local school dis- tricts], we think that people will have a much stronger view of what health care is,” Hutchenrider said. “We’ll be able to work through this, but there will be a temporary dip.” Nnoromele said the realities of the pandemic solidied his desire to help people. As a certied emergency med- ical technician, he worked as a Dallas Medical Reserve Corps COVID-19 vac- cinator at UT Dallas. Nnoromele said he would see people’s faces light up once they got the vaccine. Sawyer-McGee said the pandemic


Read our story on the Plano ISD equivalent of this program at www.communityimpact.com/pisdhealthsciencesacademy .



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First Edition: June 28, 2021

Today’s early morning highlights from the major news organizations.

A Hospital Charged $722.50 To Push Medicine Through An IV. Twice. 

Claire Lang-Ree was in a lab coat taking a college chemistry class remotely in the kitchen of her Colorado Springs, Colorado, home when a profound pain twisted into her lower abdomen. She called her mom, Jen Lang-Ree, a nurse practitioner who worried it was appendicitis and found a nearby hospital in the family’s health insurance network. After a long wait in the emergency room of Penrose Hospital, Claire received morphine and an anti-nausea medication delivered through an IV. She also underwent a CT scan of the abdomen and a series of tests. (Bichell, 6/28)

Covid’s Lingering Effects Can Put The Brakes On Elective Surgeries 

The week before Brian Colvin was scheduled for shoulder surgery in November, he tested positive for covid-19. What he thought at first was a head cold had morphed into shortness of breath and chest congestion coupled with profound fatigue and loss of balance. Now, seven months have passed and Colvin, 44, is still waiting to feel well enough for surgery. His surgeon is concerned about risking anesthesia with his ongoing respiratory problems, while Colvin worries he’ll lose his balance and fall on his shoulder before it heals. (Andrews, 6/28)

Children And Covid: Journalists Explore Grief And Vaccine Side Effects 

KHN senior correspondent JoNel Aleccia discussed grief among the estimated 46,000 children in the U.S. who lost a parent to covid-19 on NBC News NOW on Tuesday. … KHN senior correspondent Sarah Varney discussed one family’s reckoning with racism after a police shooting on NPR/WBUR’s “Here & Now” on Monday. … California Healthline editor Arthur Allen discussed children and the covid vaccine on KGO-810’s “The Chip Franklin Show” on Monday. (6/26)

Doctors’ Lobby Scores ‘Major Victory’ On Bill To Hold Physicians Accountable

The board that licenses and disciplines doctors in California is failing to hold bad actors accountable, endangering patients in the process. That’s the verdict of state lawmakers and patient advocates who have been working for years to reform the Medical Board of California. But an attempt this year to give the board more money and power to investigate complaints of fraud, gross negligence, sexual misconduct and other misbehavior is under attack from one of the most politically potent forces in California’s Capitol: doctors themselves. And so far, it seems, the doctors are winning. (Young, 6/28)

The Hill:
Calls Rise For FDA To Fully Approve COVID-19 Vaccines 

Calls are rising from some experts for the Food and Drug Administration (FDA) to move faster to fully approve the COVID-19 vaccines, in what could be a key step to address vaccine hesitancy. As the vaccination rate lags, with the country on pace to miss President Biden’s goal of vaccinating 70 percent of adults by July 4, polling indicates full approval could help convince some of the remaining unvaccinated people to get the shots.  (Sullivan, 6/27)

CBS News:
Arkansas Governor Says Final FDA Approval Of COVID-19 Vaccine Would Help Fight Hesitancy 

Arkansas Governor Asa Hutchinson said Sunday he believes final, non-emergency use approval from the Food and Drug Administration (FDA) of coronavirus vaccines would help combat hesitancy among Arkansas residents to get their shots. “Whenever they see emergency use authorization, then they say, well, they haven’t made a final approval, they haven’t got all the research completed that is needed on there. They want to do more study. And so it was approved as emergency use,” Hutchinson, a Republican, said in an interview on “Face the Nation.” “And so for that reason, you can’t mandate it. We don’t mandate it in Arkansas. We have to rely upon the education.” (Quinn, 6/27)

The Hill:
Bipartisan Senators Ask CDC, TSA When They Will Update Mask Guidance For Travelers 

A bipartisan group of senators has asked the Centers for Disease Control and Prevention (CDC) and Transportation Security Administration (TSA) when they will update their mask guidance for travelers. In a letter, Sens. Brian Schatz (D-Hawaii), Roger Wicker (R-Miss.), Amy Klobuchar (D-Minn.), Susan Collins (R-Maine), and Jerry Moran (R-Kan.) requested information about the agency’s process for updating the mask guidelines for vaccinated people, adding that they want answers by July 12. (Oshin, 6/27)

Fox News:
WHO Recommends Masks — Even For Vaccinated People — Because Of Delta Variant

As the highly contagious delta variant of the coronavirus gained traction around the world, the World Health Organization urged vaccinated people to continue to wear masks and social distance, according to reports. “Vaccine alone won’t stop community transmission,” Dr. Mariangela Simao, WHO’s assistant director-general for access to medicines and health products, said during a briefing in Geneva, according to CNBC. “People need to continue to use masks consistently, be in ventilated spaces, hand hygiene … the physical distance, avoid crowding. This still continues to be extremely important, even if you’re vaccinated when you have a community transmission ongoing.” (Stimson, 6/27)

Booster May Be Needed For J&J Shot As Delta Variant Spreads, Some Experts Already Taking Them

Infectious disease experts are weighing the need for booster shots of the Pfizer/BioNTech or Moderna mRNA-based vaccines for Americans who received Johnson & Johnson’s (JNJ.N) one-dose vaccine due to the increasing prevalence of the more contagious Delta coronavirus variant. A few say they have already done so themselves, even without published data on whether combining two different vaccines is safe and effective or backing from U.S. health regulators. Canada and some European countries are already allowing people to get two different COVID-19 shots. (Erman, 6/27)

Los Angeles Times:
Highly Contagious Delta Coronavirus Variant Spreading Fast In California

The Delta coronavirus variant is now the third-most common in California, new data show, underscoring the danger of the highly contagious strain to people who have not been vaccinated against COVID-19. The variant makes up 14.5% of California coronavirus cases analyzed so far in June, up from 4.7% in May, when it was the fourth-most identified variant in California, according to data released by the California Department of Public Health. (Lin II, Money and Wigglesworth, 6/27)

The Wall Street Journal:
How Mutations Have Shaped The Covid-19 Pandemic 

Based on a recent government projection, the Delta variant of the Covid-19 virus could become the dominant type of this coronavirus in the U.S. within a month, making it one of most aggressive variants to take hold in the country. Delta is the latest in a series of variants that have spread throughout the U.S. Like all viruses, coronaviruses mutate as they reproduce. Some of these genetic changes make them better at infecting human cells or evading our immune defenses. As newer, better-adapted variants emerge, they push aside earlier versions of the virus. Here is a look at how this process has played out across the U.S. since the start of the pandemic. (Ulick, 6/27)

As Variant Rises, Vaccine Plan Targets ‘Movable Middle’

Thrown off-stride to reach its COVID-19 vaccination goal, the Biden administration is sending A-list officials across the country, devising ads for niche markets and enlisting community organizers to persuade unvaccinated people to get a shot. The strategy has the trappings of a political campaign, complete with data crunching to identify groups that can be won over. But the message is about public health, not ideology. The focus is a group health officials term the “movable middle” — some 55 million unvaccinated adults seen as persuadable, many of them under 30. (Alonso-Zaldivar, 6/27)

Arkansas Governor Trying To Reverse His State’s Trends On Vaccination

Arkansas Gov. Asa Hutchinson said Sunday that hospitalizations are up among those who are unvaccinated and that vaccinations have slowed, a worrying trend among several states across the country. Hutchinson said on CBS News’ “Face the Nation” that “people started feeling comfortable” after vaccines were first doled out. “People saw the cases of hospitalizations go down. And so, the urgency of getting the vaccine slowed down,” he said. (Bice, 6/27)

The New York Times:
As Parents Forbid Covid Shots, Defiant Teenagers Seek Ways To Get Them 

Teenagers keep all sorts of secrets from their parents. Drinking. Sex. Lousy grades. But the secret that Elizabeth, 17, a rising high-school senior, keeps from hers is new to the buffet of adolescent misdeeds. She doesn’t want her parents to know that she is vaccinated against Covid-19. Her divorced parents have equal say over her health care. Although her mother strongly favors the vaccine, her father angrily opposes it and has threatened to sue her mother if Elizabeth gets the shot. Elizabeth is keeping her secret not only from her father, but also her mother, so her mom can have plausible deniability. (Hoffman, 6/26)

Rush To Close Vaccination Gap For Hispanics

Troves of misinformation, language barriers and fears around immigration enforcement are hampering efforts to vaccinate Hispanic communities against Covid-19, challenging the Biden administration’s push to crush the coronavirus as a dangerous new variant quickly spreads. Much of the nationwide attention on the slowing vaccination campaign has focused on hard-line resisters, predominately in Republican-led states in the South and Mountain West. But Hispanic communities, even as they’re among the most eager to receive the shots, are still facing barriers to vaccination that could leave them vulnerable to the virus this summer, according to interviews with nearly two dozen people working on vaccination efforts, including state officials and community groups. (Roubein and Goldberg, 6/27)

San Francisco Chronicle:
Vaccination Clinic Serves Local Deaf Community As Alameda County Shifts From Mass Sites

Speaking in sign language, Jacqueline Augustine said her right arm hurt after she received her first dose of the coronavirus vaccine on Saturday. Augustine received the shot at a small pop-up clinic inside the Deaf Counseling Advocacy and Referral Agency in San Leandro. The clinic was designed to attract people from the deaf and hearing-impaired community as well as anyone else in the area who still needs a vaccination. “My family was so worried about me,” said Augustine, who was going to get a shot in March but developed a skin infection that kept her housebound for months. “My family was encouraging me. My doctor was, too. He said it’s time.” (Cabanatuan, 6/26)

The New York Times:
Prisoners Sent Home Because Of Covid May Have To Go Back 

In the final days of the Trump administration, the Justice Department issued a memo saying inmates whose sentences lasted beyond the “pandemic emergency period” would have to go back to prison. But some lawmakers and criminal justice advocates are urging President Biden to revoke the rule, use his executive power to keep them on home confinement or commute their sentences entirely, arguing that the pandemic offers a glimpse into a different type of punitive system in America, one that relies far less on incarceration. (Kanno-Youngs and Turcotte, 6/27)

Fox News:
FDA Authorizes Roche Drug For Severely Ill COVID-19 Patients

The Food and Drug Administration granted emergency approval to Roche’s Actemra (tocilizumab) to boost outcomes among hospitalized COVID-19 patients receiving oxygen and steroid medications. Data from clinical trials among over 5,600 hospitalized patients indicated infusions, in addition to routine care, cut patients’ length of hospital stay and reduced the risk of death and ventilation after 28 days of follow-up. (Rivas, 6/26)

USA Today:
Immunocompromised Must Be Cautious, COVID Vaccines Not As Protective

Dr. Robert Montgomery had several reasons for getting a COVID-19 vaccine as soon as he could. As a transplant surgeon at a busy New York hospital, his patients were among the most vulnerable to the disease. The pandemic has exacted a terrible toll on transplant recipients. About 20% of those infected died – almost 2,000 in New York City alone last year compared to just one or two transplant patient deaths in a typical flu season, Montgomery said.He also is a transplant patient himself. The heart beating inside his 61-year-old chest is not the one he was born with. (Weintraub, 6/27)

One COVID Vaccine Dose Yields Good Protection In Elderly, 2 Studies Find 

As COVID-19 vaccines were first being approved for emergency use in the United Kingdom, the UK Joint Committee on Vaccination and Immunisation decided to extend the interval before the second dose from 4 to 12 weeks to maximize the amount of people who could be vaccinated. This week, two Lancet Infectious Diseases studies estimated vaccine effectiveness (VE) for the elderly after receiving just one dose. (McLernon, 6/25)

USA Today:
COVID: Loss Of Taste And Smell Could Last Up To A Year, Study Says

COVID-19 survivors who lost their sense of taste and smell may have to wait up to a year to fully recover, a new study found. Researchers followed 97 COVID-19 patients who lost their sense of taste and smell for an entire year and asked them to complete a survey every four months, according to the study published Thursday in JAMA Network Open.Out of 97 patients, 51 of them also were asked to undergo objective testing to corroborate the self-reported surveys. At eight months, 49 out of the 51 patients had fully recovered their sense of taste and smell. (Rodriguez and Rice, 6/25)

The New York Times:
Infrastructure Deal Is Back On Track After Biden’s Assurances 

A fragile bipartisan infrastructure deal appeared to be moving forward once again on Sunday, as moderate Republicans said they had been reassured that President Biden would not hold it hostage while Democrats simultaneously work on a larger, partisan economic package. After 48 hours of chaos, the statements by leading Republicans prompted a sigh of relief for the White House, where Mr. Biden and top aides had worked through the weekend to keep the eight-year, $1.2 trillion investment to rebuild the nation’s infrastructure from falling apart. G.O.P. negotiators even suggested that they could now begin drafting the bill and said they believed it would win enough Republican votes to pass the Senate next month. (Fandos, 6/27)

The Washington Post:
Housing Crisis Poses Crucial Test For Biden Administration’s Economic Plans 

Housing has emerged as one of the most unequal and consequential parts of the economic recovery from the coronavirus pandemic. Low interest rates, cheap mortgages and bidding wars are fueling a housing boom for wealthier Americans and making homeownership out of reach for many first-time buyers. Meanwhile, housing is a top expense and worry for millions of renters and unemployed workers, and advocates fear a wave of homelessness once the CDC’s final moratorium lifts July 31. (Siegel, 6/27)

The Wall Street Journal:
Americans Are Leaving Unemployment Rolls More Quickly In States Cutting Off Benefits

The number of unemployment-benefit recipients is falling at a faster rate in Missouri and 21 other states canceling enhanced and extended payments this month, suggesting that ending the aid could push more people to take jobs. Federal pandemic aid bills boosted unemployment payments by $300 a person each week and extended those payments for as long as 18 months, well longer than the typical 26 weeks or less. The benefits are set to expire in early September, but states can opt out before then. (Morath and Barrett, 6/27)

The New York Times:
Where Jobless Benefits Were Cut, Jobs Are Still Hard To Fill 

By lunchtime, the representatives from the recruiting agency Express Employment Professionals decided to pack up and leave the job fair in the St. Louis suburb of Maryland Heights. Hardly anyone had shown up. “We were hoping we would see prepandemic levels,” said Courtney Boyle, general manager of Express. After all, Missouri had just cut off federal unemployment benefits. (cohen, 6/27)

Houston Chronicle:
Thousands Of Texans File Lawsuit Against Gov. Abbott For Ending Federal Unemployment Benefits

Thousands of Texans have banded together and hired an attorney to file suit to block Gov. Greg Abbott from ending emergency federal unemployment benefits before the programs expire in September. The plaintiffs, two groups that organized over Facebook with more than 30,000 people, argue that the decision to end the benefits early exceeded the governor’s authority, according to the lawsuit, filed this week in state district court in Austin. The benefits, aimed at providing relief to workers during the pandemic, are scheduled to expire Saturday under Abbott’s order. (Carballo, 6/25)

NBC News:
Biden’s Pledge To Boost Home Caregiver Funding Excluded From Infrastructure Deal

When Morgan Champion brought her 74-year-old father home to live with her, she had little time to prepare. It was early May when she and her sister had found him emaciated and sitting in a soiled diaper at his memory care facility in Tallahassee, Florida, after the pandemic lockdown finally lifted.“We really felt like dad was in danger,” Champion said. The family needed to get him out as quickly as possible. … “I want him to have the dignity of being taken care of well,” Champion, 34, said. “It’s definitely been a struggle.” (Khimm, 6/26)

Some Disabled Californians Feel Abandoned By Newsom’s Golden State Stimulus

While California lawmakers automatically sent checks to 1.2 million people who receive SSI, the 1.2 million Californians on SSDI only qualify if they had income from work in 2020. But that’s rare — research shows that fewer than one in five SSDI recipients work during a typical year, often because they are limited by their disabilities or risk losing their benefits if they work too much. Disability advocates say it’s the latest example of the state abandoning some of its most vulnerable residents during the pandemic, after having directed medical health providers to ration COVID-19 care to elderly and less healthy people last spring and deprioritize people with disabilities for vaccines earlier this year — both policies that were reversed after considerable outcry. (Botts, 6/26)

San Francisco Chronicle:
Health Care For Undocumented Seniors, $600 Stimulus Checks Coming In Next California Budget

Facing a looming deadline, legislative budget officials said late Friday they had reached a framework for the state budget with Gov. Gavin Newsom, hashing out agreements on homelessness funding, health coverage for undocumented seniors and other lingering policy differences. But the officials, who declined to speak on the record, said some key details remained unsettled, even as the Legislature prepares to pass the $262.2 billion spending plan on Monday, three days before the start of the new fiscal year. (Koseff, 6/26)

House Leaders To Investigate FDA Approval, Price Of New Alzheimer’s Drug 

The top House Democrats on two powerful committees on Friday announced an investigation into the approval and pricing of Biogen’s controversial Alzheimer’s drug, Aduhelm. Both Biogen and the Food and Drug Administration will be under the microscope, House Committee on Oversight and Reform Chair Carolyn Maloney (D-N.Y.) and Energy and Commerce Chair Frank Pallone (D-N.J.) said. (Cohrs, 6/25)

Modern Healthcare:
High Costs, High Deductibles Inspire Consumers To Pay Cash For Drugs

If innovation is the mother of necessity, the market for disrupting the pharmacy industry could be limitless. Attention to the cost of prescription drugs intensified this month when the Food and Drug Administration approved the Alzheimer’s disease drug Aduhelm, which manufacturer Biogen has priced at $56,000. But for policymakers, payers and patients, high drug prices are nothing new. Nearly 90% of consumers believe the federal government should negotiate directly with the drugmakers to drive down prices, according to a June poll by the Kaiser Family Foundation. Respondents across the political spectrum agreed that lowering prescription costs should be a key priority for President Joe Biden’s administration. (Tepper, 6/25)

Modern Healthcare:
Senators Urge Biden Admistration To Protect Patients From Harsh Medical Debt Collections

Senate Democrats are calling on federal authorities to take action on aggressive medical debt collection, citing reports about hospitals suing patients over unpaid bills. In a letter to the the Consumer Financial Proection Bureau (CFPB), Democratic Sens. Chris Murphy (Conn.) and Chris Van Hollen (Md.) recommended a series of actions to protect consumers’ credit scores, provide patients with more information about financial assistance and coverage options, and give them more time to dispute or resolve debts before they are sent to collections. (Hellman, 6/25)

Modern Healthcare:
CMS Doesn’t Know If Hospitals Are Ready For The Next Pandemic

CMS can’t ensure that hospitals are prepared for emerging infectious disease threats like COVID-19, according to a federal watchdog report released Monday. Although the agency announced in February 2019 that hospitals had to plan for potential outbreaks, CMS can’t confirm that all hospitals have updated their emergency preparedness plans during the pandemic because it only inspects them every three to five years, HHS’ Office of Inspector General said in its report. That’s mainly because CMS can’t require accrediting organizations, which inspect about 90% of Medicare and Medicaid-approved hospitals, to carry out more frequent quality and safety surveys or targeted infection control inspections. (Brady, 6/28)

Modern Healthcare:
Medicaid Work Rules In Arizona, Indiana Scrapped By CMS

The Centers for Medicare and Medicaid Services pulled the plug on Arizona’s and Indiana’s plans to require some Medicaid beneficiaries to work, attend job training or participate in other activities to keep their health coverage, according to letters the federal agency sent the two states Friday. The waivers President Donald Trump’s administration approved were unlikely to promote the objectives of Medicaid, which federal courts have ruled is to provide health insurance, CMS Administrator Chiquita Brooks-LaSure wrote in the letters. The pandemic also presents challenges to the Medicaid population that make work requirements especially burdensome, she wrote. At this time, beneficiaries may lack access to economic opportunities, transportation and affordable childcare as the public health emergency gradually winds down. Imposing a work requirement under these circumstances could lead to unfair benefit losses, she wrote. (Brady, 6/25)

Modern Healthcare:
J&J To Stop Selling Opioids, Agrees To $230M Settlement With NY

Johnson & Johnson has agreed to pay $230 million to New York state to settle claims that the pharmaceutical giant helped fuel the opioid crisis, Attorney General Letitia James said on Saturday. The drugmaker also agreed to permanently end the manufacturing and distribution of opioids across New York and the rest of the nation, James said in a statement announcing the settlement. The company “helped fuel this fire, but today they’re committing to leaving the opioid business—not only in New York, but across the entire country,” she said. (6/26)

Johnson & Johnson Agrees To Pay $230 Million To Settle N.Y. Opioid Case

On the eve of a widely anticipated trial, Johnson & Johnson (JNJ) agreed on Saturday to pay $230 million to the state of New York to settle a lawsuit alleging that the company helped fuel the devastating opioid crisis. The deal comes as negotiations intensify with the health care giant and three of the nation’s largest pharmaceutical wholesalers to complete a sweeping $26 billion settlement of thousands of other lawsuits. The settlement includes an additional $33 million in attorney fees and costs, as well as a commitment from J&J to halt opioid sales, a step the company said it has already taken (you can read the settlement here). (Silverman, 6/26)

In A First For Genome Editing, Intellia Reports Positive Data On In Vivo CRISPR Therapy

In a major milestone for the still-young field of genome editing, Intellia Therapeutics said Saturday that the first six patients to receive a CRISPR-based treatment for a genetic nerve disorder have safely had the DNA inside their liver cells edited. Preliminary results from the study — the first to show that CRISPR-based gene editing can be delivered systemically and performed in vivo, or inside the body  — found that the treatment reduced levels of a disease-causing protein by an average of 87% in the higher dose cohort with only mild side effects. The encouraging interim Phase 1 results, presented at a conference on Saturday, were published simultaneously in the New England Journal of Medicine. (Molteni, 6/26)

Modern Healthcare:
Bright Health Raises $924 Million In Largest Insurtech IPO Of 2021

Bright Health raised $924 million on a valuation of approximately $12 billion during its initial public offering on Thursday, with the Minneapolis-based insurtech booking the largest IPO among the health insurance startups that went public this year. The company’s shares failed to reach their estimated price of $18 during the IPO, meaning its valuation fell about $2 billion short of what investors expected. Bright Health is the last of the insurtechs expected to make an IPO this year, with Alignment Healthcare, Oscar Health and Clover Health all going public earlier in 2021. (Tepper, 6/25)

Modern Healthcare:
San Diego Sues Molina, HealthNet, Kaiser

The city of San Diego sued three health insurers on Friday, alleging Kaiser Permanente, HealthNet and Molina Healthcare all advertised false networks of providers in an attempt to get consumers to sign up for their plans. The three insurers together enrolled more than 3.3 million California residents in 2019, and “are among the worst actors in California when it comes to the inaccuracy of their provider networks,” according to the three separate suits, all filed in San Diego Superior Court. (Tepper, 6/25)

New ASU Havasu Program Aims To Help Address Nurse Shortage

Even before the pandemic, a scarcity of nurses was an ongoing concern in Arizona especially in more rural areas. An Arizona State University nursing program, set to debut at the school’s Lake Havasu City campus this fall, aims to put a dent in that shortage. ASU Havasu, which is still a young campus at 9 years old, got approval in April from the Arizona Board of Nursing to offer a 12-month bachelor of science degree in nursing. The program is expected to draw more than 30 new students, the Today’s News-Herald reported. (6/27)

The Boston Globe:
Region’s Lab Space Boom Continues As High-Rise Moves Forward In Malden

A developer has won approval for a nine-story office building in downtown Malden that would add to a cluster of projects seeking to attract life-sciences companies to the city center. The Malden City Council on June 22 signed off on the planned project by Quaker Lane Capital at 11 Dartmouth Street, where the developer says it intends to create space for retail, with offices above “targeted at innovation-driven tenants, including public and private sector organizations as well as entrepreneurial and research and development focused firms.” The 160,000-square-foot project comes as developers throughout the region are investing heavily in lab space, betting that life sciences will be a key to the future of the Boston’s economy. In Malden, additional office space is coming online to support companies working on research and development. (Rosen, 6/27)

Crain’s New York Business:
How New York’s Health Systems Are Advancing Care For LGBTQ Communities

June might be Pride month, but the work to ensure better access to healthcare for the LGBTQ community happens all year round. Health networks including NYC Health + Hospitals and Stony Brook Medicine have built clinics and care centers in areas of need. Earlier this month, the city public health system opened a gender-affirming integrated services practice in the South Bronx—its first such facility in the borough. Similarly, the Long Island health network brought LGBT-specialized care to the East End with a new, 2,000-square-foot, $750,000 health center. Robert Chaloner, chief administrative officer at Stony Brook Southampton Hospital, says he hopes the center will inspire other facilities to spring up in the future. (Sim, 6/25)

Experts Debate The Value Of Digital Coaching For Type 2 Diabetes

Even before the pandemic drove an extreme shift toward telemedicine, diabetes care was leading the march toward digital care. A crop of health care companies including Onduo, One Drop, Lark Health, Omada, Livongo, and Virta Health have built businesses on the idea that virtual coaching and remote monitoring can help people with diabetes keep their glucose levels in healthier ranges. Next year, estimates suggest the market for digital diabetes care will exceed $700 million. (Palmer, 6/28)

The Washington Post:
Prohibited, Unlisted, Even Dangerous Ingredients Turn Up In Dietary Supplements

When buying a dietary supplement, you probably assume that what’s on the label is what’s in the pill. But this assumption doesn’t always hold up, says Pieter Cohen, a physician at Cambridge Health Alliance. In March, Cohen published his 14th paper concerning dietary supplements that contained either prohibited or unlisted ingredients. This time, he and his colleagues analyzed 17 brands of sports and weight-loss supplements sold in the United States, and they detected nine prohibited stimulants in them. Almost half of the brands tested included more than one prohibited stimulant. (Aschwanden, 6/26)

The New York Times:
Helping Drug Users Survive, Not Abstain: ‘Harm Reduction’ Gains Federal Support 

The thin young man quietly took in the room as he waited for the free supplies meant to help him avoid dying: sterile water and cookers to dissolve illicit drugs; clean syringes; alcohol wipes to prevent infection; and naloxone, a medicine that can reverse overdoses. A sign on the wall — “We stand for loving drug users just the way they are” — felt like an embrace. It was the first day the drop-in center in a residential neighborhood here had opened its doors since the coronavirus forced them shut in the spring of 2020. “I’m so glad you all are open again,” the man, whose first name is Jordan, told a volunteer who handed him a full paper bag while heavy metal music riffed over a speaker in the background. He asked for extra naloxone for friends in his rural county, an hour away, where he said it had been scarce throughout the pandemic. (Goodnough, 6/27)

The Washington Post:
Two Young Unvaccinated Passengers On Royal Caribbean Cruise Test Positive For Covid-19

Two young unvaccinated passengers on a Royal Caribbean International cruise out of the Bahamas tested positive for the coronavirus, the cruise line said. The passengers, who were younger than 16 and traveling in the same group, left Adventure of the Seas before the end of the cruise on Thursday in Freeport with their companions. They returned home to Florida on a private flight arranged by the cruise company, CEO Michael Bayley said in a Facebook post. (Sampson, 6/25)

USA Today:
TSA Reports Highest Number Of Travelers Since March 2020

Next Sunday marks the Fourth of July, President Joe Biden’s target date of getting 70% of adult Americans at least partially vaccinated for COVID-19. But the White House last week said that wasn’t predicted to happen. Getting at least one shot into the arms of 70% of all American adults will take a few more weeks, said Jeff Zients, the White House coronavirus response coordinator. But with Transportation Security Association screening numbers trending upward, including its highest recorded number since March 7, 2020 reported Friday, neither the faulty prediction nor variants is not predicted to deter holiday revelry.  The spread of the delta variant of COVID-19 into the U.S. is becoming a concern for medical experts because of pockets of people in the nation who have yet to receive the vaccine. (Aspegren and Vargas, 6/28)

Backyard Poultry Salmonella Outbreak Grows To 474 Cases, 1 Death

A US Salmonella outbreak linked to backyard poultry has grown by 311 cases, to 474 illnesses, and the CDC has reported the first outbreak death, according to a CDC update yesterday. Three more states are affected (46 total) and a new serotype has been added (Salmonella Mbandaka) since the CDC’s first notice of the outbreak on May 20. An Indiana patient has died. … Of 271 people interviewed, 209 (77%) reported contact with backyard poultry before getting sick. (6/25)

Fox News:
NJ Man Contracts Rare Mosquito-Borne Virus: What Is Jamestown Canyon Virus?

Health officials in New Jersey confirmed the state’s first mosquito-borne disease of the year after a man in his sixties from Sussex County tested positive for Jamestown Canyon virus. The unnamed patient experienced onset of fever and neurological symptoms in May, the state health department announced this week. The patient had not traveled, and was released from the hospital to a long-term rehabilitation center last week, a spokesperson for the health department told Fox News. The case marks the state’s second such reported infection; the first case occurred in 2015 in Sussex County. (Rivas, 6/26)

The Washington Post:
Parents Are Struggling To Get Kids Off Screens After The Pandemic 

The week after Rebecca Grant took away her kids’ video games for a month, after a year of relaxed pandemic rules, her 10-year-old son was livid. He gave her the silent treatment, mostly ignoring her except to spit out a hurtful “I don’t love you” one night at bedtime. The ban wasn’t an easy decision for Grant. The 46-year-old mom of two from Fremont, Calif., did hours of research and read multiple books from parenting experts. She joined Facebook groups for families in similar situations and closely watched her children’s behavior, which had been worrisome for a while. Still, she was caught off guard by the reaction. (Kelly, 6/26)

ABC News:
When Cancer And Gender Identity Collide: Transgender Patients Fight Stigma And Disease 

Receiving a cancer diagnosis can be scary and life-altering. It takes strength to navigate the world following a diagnosis, so any additional barriers to this process can be tough, such as for transgender patients. Although the world of medicine largely remains a cisgendered world, the landscape is changing to include more research, advocacy and education about transgender patients. (Okolo, 6/27)

WVa Chief Justice Suspends Some Court Health Protocols

West Virginia Chief Justice Evan Jenkins has suspended many of the court health protocols that arose last year from the coronavirus pandemic. Jenkins’ administrative order contained some exceptions. Courts should continue using remote technology when possible for hearings and proceedings, Jenkins’ order said. They should also continue avoiding the use of call dockets to cut back on extended waiting periods in lobbies, common areas and court rooms, he wrote. (6/28)

CDC Gives Maine $7M To Prep For Future Public Health Crises

The federal government has given Maine a $7 million boost to help prepare for another public health crisis. Republican Sen. Susan Collins and independent Sen. Angus King said the Maine Department of Health and Human Services has received the money from the U.S. Centers for Disease Control and Prevention. About $1.8 million of the money is for preventing and controlling emerging diseases and the rest is for preparing and responding to public health emergencies. (6/27)

Montana To Use Federal Money To Boost Child Care Capacity

More than $30 million of federal funding could be directed toward expanding child care capacity in Montana under recommendations approved by a state health advisory commission. The commission approved up to $31 million for the state health department to administer grants to expand child care in the state, the Montana State News Bureau reported Thursday. The commission, which is made up of three members of the executive branch and seven lawmakers, is tasked with directing coronavirus relief dollars. (6/27)

The Advocate:
Louisiana State Worker Insurance To Cover Obesity Surgery After Governor Signs Bill Into Law

Louisiana’s health insurer for state workers, teachers and retirees will soon cover weight loss surgery for people who are obese, under a bill signed into law by Gov. John Bel Edwards. Sen. Regina Barrow, a Baton Rouge Democrat, had previously tried to get the Office of Group Benefits to cover gastric bypass surgery and other types of weight loss surgeries, to lessen the health conditions associated with obesity. But lawmakers had raised concern about the costs. Barrow made some adjustments to the legislation and won unanimous support from the House and Senate in the recently ended legislative session. The governor agreed to the idea and signed the bill, which will take effect Aug. 1. (6/26)

SC Officials Offer Free Testing For HIV, Sexual Diseases

To mark National HIV Testing Day, South Carolina health officials are offering free testing for HIV and sexually transmitted diseases later this week. The free testing is Tuesday at several local health departments across the state, the Department of Health and Environmental Control said in a statement. (6/27)

The Boston Globe:
Holyoke Soldiers’ Home COVID-19 Probe Raises Questions About Independence

When 76 veterans died last spring of COVID-19 in the Holyoke Soldiers’ Home, the need to get to the bottom of what happened and why, and who was to blame, could hardly have been more clear. So when Governor Charlie Baker tapped a private attorney to conduct an independent investigation, it seemed like the moment for one of those no-stone-unturned independent probes that have made history here. But a Boston Globe Spotlight Team review of Baker’s arrangement with former prosecutor Mark Pearlstein — including communications between the governor’s office and Pearlstein — raises troubling new questions about whether the investigation was truly independent. The legal contract between the Office of the Governor and Pearlstein’s law firm created an explicit attorney-client relationship, which could be used to keep their communications and other materials private and suggested Pearlstein was working for Baker, not the public. (Estes and Ostriker, 6/26)

New U.K. Health Chief Is Ex-Deutsche Man Keen To End Virus Rules

Sajid Javid’s return to Boris Johnson’s top team as health secretary seals a speedy comeback for one of the political heavyweights of the Conservative Party, a one-time managing director at Deutsche Bank AG who is expected to push for a timely end to Britain’s coronavirus restrictions. Replacing Matt Hancock following his dramatic resignation over the weekend, Javid is more likely to support easing coronavirus rules than his predecessor, according to former Javid aide Salma Shah, speaking on BBC TV on Sunday. (Mayes, 6/28)

Fox News:
Over 2 Million Likely Had Long COVID-19 In England, Study Estimates

A new study projects more than 2 million adults in England likely experienced persistent symptoms in the months following COVID-19 infection, or so-called long COVID. Researchers affiliated with Imperial College London released findings Thursday, stemming from over half a million people in England who participated in several rounds of the Real-Time Assessment of Community Transmission-2 (REACT-2) study, which invited random samples of adults to take surveys from September to February. “Long COVID, describing the long-term sequelae after SARS-CoV-2 infection, remains a poorly defined syndrome. There is uncertainty about its predisposing factors and the extent of the resultant public health burden, with estimates of prevalence and duration varying widely,” authors prefaced. (Rivas, 6/26)

South Africa Tightens Restrictions To Fight Resurgent Virus

Battling a fast-increasing surge of COVID-19 cases, South Africa has reintroduced tough restrictions including a ban on alcohol sales and an extended nightly curfew. The delta variant, first discovered in India, appears to be driving South Africa’s new increase, President Cyril Ramaphosa said Sunday night, announcing the return to strict measures. South Africa recorded more than 15,000 new cases Sunday, including 122 deaths, bringing its total fatalities to near 60,000. (Magome and Meldrum, 6/27)

This is part of the KHN Morning Briefing, a summary of health policy coverage from major news organizations. Sign up for an email subscription.

Competitive Bioinformatics Market Updates, CAGR Status,

Bioinformatics market

The Business Research Company offers “Bioinformatics Global Market Report 2021: COVID-19 Growth And Change To 2030” in its research reports store. This is the most comprehensive report available in this market and it will help to gain a truly global perspective as it covers 60 geographies. The regional and country breakdown section gives an analysis of the market in each geographic area and the market size by region and country. It also compares historical and forecast market growth and highlights important trends and strategies that market players can adopt.

The Bioinformatics Market report describes and explains the global bioinformatics market and covers 2015 to 2020, referred to as historical period, and 2020 to 2025, referred to as forecast period, along with other forecasts for the period 2025-2030. The report assesses the market in each region and for the major economies in each region.

Place a direct report purchase order here

The bioinformatics market includes sales of bioinformatics and related services. Bioinformatics combines computer programming, information engineering, mathematics, and statistics to analyze biological data for drug discovery and for preclinical studies.

The global bioinformatics market is expected to grow from $ 9.38 billion in 2020 to $ 10.57 billion in 2021 at a compound annual growth rate (CAGR) of 12.7%. The growth is mainly due to businesses resuming their activities and adapting to the new normal while recovering from the impact of COVID-19, which previously led to restrictive containment measures involving social distancing, remote work and closure of business activities which resulted in operational challenges. The bioinformatics market is expected to reach $ 18.46 billion in 2025 at a CAGR of 15%.

Request a sample of the bioinformatics market here:

Some of the major players in the bioinformatics market are Agilent Technologies, Illumina, QIAGEN, Affymetrix, and Thermo Fisher Scientific.

The countries covered in the global bioinformatics market are Argentina, Australia, Austria, Belgium, Brazil, Canada, Chile, China, Colombia, Czech Republic, Denmark, Egypt, Finland, France, Germany, Hong Kong, India, Indonesia, Ireland, Israel, Italy, Japan, Malaysia, Mexico, Netherlands, New Zealand, Nigeria, Norway, Peru , Philippines, Poland, Portugal, Romania, Russia, Saudi Arabia, Singapore, South Africa, South Korea, Spain, Sweden, Switzerland, Thailand, Turkey, United Arab Emirates, United Kingdom, United States, Venezuela, Vietnam.

The regions covered in the Global Bioinformatics Market are Asia Pacific, Western Europe, Eastern Europe, North America, South America, Middle East & Africa .

The global bioinformatics market is segmented –
1) By products and services: knowledge management tools, data analysis platforms, services
2) By application: metabolomics, molecular phylogenetics, transcriptomics, proteomics, chemoinformatics, genomics, others
3) By end users: pharmaceuticals, animal studies, agriculture, forensic science, other end users

Learn more about the Global Bioinformatics Market report:

Some points from the table of contents
1. Summary
2. Characteristics of the bioinformatics market
3. Bioinformatics Market Trends and Strategies
4. Impact of COVID-19 on bioinformatics
5. Size and growth of the bioinformatics market
27. Bioinformatics Market Competitive Landscape and Company Profiles
28. Key mergers and acquisitions in the bioinformatics market
29. Future prospects of the bioinformatics market and potential analysis
30. Annex

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COVID-19 cases on the rise in Clark County, raising concerns for those fully vaccinated

LAS VEGAS (KLAS) – As COVID-19 cases increase in Clark County, there are new fears of contracting the virus, even if you are fully vaccinated.

Many of those who have received their full vaccination also wonder if the cough or fever means they are infected.

Experts say it’s important to remember that the pandemic is not over yet. As Nevada has reopened and mask warrants have faded, everyone still needs to be vigilant. This includes cases where people who have been fully vaccinated start to feel sick.

The COVID Delta variant is more transmissible and local vaccination rates are leveling off.

“I think that’s something to be concerned about a bit,” said Dr. Christina Madison, associate professor of pharmacy practice at Roseman University of Health Sciences.

While those who are fully vaccinated are less likely to be hospitalized, there is still a small chance of ending up with the virus.

“We know the vaccine is not a quick fix, but it is extraordinarily effective,” Madison said. “Even in the face of these variants, this is your best defense against this virus.”

So what if you are completely immune and suddenly feel sick? How do you know if it’s a rare case of COVID or just a cold?

“Unfortunately, it’s really not possible to distinguish whether or not you have COVID, the Delta variant or sometimes even the common cold,” said Dr. Marc J. Kahn, dean of the Kirk Kerkorian School of Medicine at UNLV. . “The only way to know for sure if you have COVID is to get tested for COVID. “

Experts add that an increase in the common cold is not expected given all the steps we have taken to prevent COVID and now that masks are no longer mandatory.

“We’re going to see an increase in some of these other transmissible viruses,” Kahn said.

Even in these cases, it is recommended to be careful.

“If you’re sick of anything, you shouldn’t go out into situations where you can pass disease on to others, whether it’s COVID or the flu or whatever,” the infectious disease epidemiologist said. Brian Labus, Assistant Professor at the UNLV School of Public Health. “You should not pass this disease on to other people.”

And as for the coronavirus, if you’re in the crowd and you’re not sure about their vaccine status:

“It’s really probably in your best interests to wear a mask, even if the CDC doesn’t require it,” Madison explained.

Since vaccination rates in Clark County have yet to reach the herd immunity threshold, state and local leaders are trying to step up their efforts. Governor Steve Sisolak announced that the state will launch more mobile vaccination units in targeted locations and recruit new providers to deliver vaccines directly to patients.

Sisodia Launches Certificate Course for Health Assistants, Health News, ET HealthWorld

New Delhi: Deputy Chief Minister Manish Sisodia on Monday launched a certificate course for health assistants and said the government wanted to equip young people with all the basic skills and knowledge to tackle any medical crisis. Noting that the Delhi government is considering making it a long-term initiative, Sisodia said within four days 1.5 lakh of people applied for the training program.

The Delhi government has disbursed Rs 5 crore for this initiative. The course was initiated in partnership with Guru Gobind Singh Indraprastha University.

“We want to create a model youth force in Delhi that will be equipped with all the basic skills and knowledge to tackle any medical crisis.

“Not only will our young people be ready to face any crisis, but they will also be able to provide medical assistance to their families and members of their community,” Sisodia said after the course was launched.

Referring to the application of 1.5 lakh of people for the program, the Deputy Chief Minister said, “This indicates that people are excited to participate in this course and learn. that and make it a long-term, ongoing initiative, ”he said.

Health Minister Satyendar Jain said the certificate course is extremely important to deal with any medical crisis in the future.

“This course will be able to provide individuals with employment opportunities as there is a growing need for health assistants in hospitals who will be able to assist nurses and doctors,” he said. he declares.

The two-week course will include 500 trainees from the first batch, who will be equipped with knowledge in life support, heart function, Covid care, blood tests, swabs, first aid, home care, etc. . the government said.

Trainees will learn how to measure oxygen, blood pressure and inject drugs, he added.

The course is divided into two stages – the first week will include didactic and demonstrative training, while the second week trainees will receive hands-on experience.

Nine Delhi hospitals have been mobilized for this course, where trainees will receive basic training.

Deen Dayal Upadhyay Hospital, Ram Manohar Lohia Hospital, Rajiv Gandhi Super Specialty Hospital, Chacha Nehru Child Clinic, Sanjay Gandhi Hospital, Ambedkar Medical College, ESIC Hospital Basaidharapur, Hindu Rao Hospital and Vardhaman Mahavir Hospital are the nine hospitals enrolled in the program, says the communicated.

The Delhi government will provide training in batches of 500, with a total of 5,000 trainees, who will receive a certificate and medical kit upon completion of the course. The medical kit includes a blood pressure monitor, a thermometer and an oximeter.

Earlier this month, Chief Minister Arvind Kejriwal announced that his government would train 5,000 young people to help doctors and nurses as part of its preparations for a possible third wave of COVID-19.

Community health assistants or nursing assistants will receive a two-week basic training in nursing and life care. Training will begin from June 28 in batches of 500 candidates, he said.

Improve drug-receptor interactions to improve drug efficacy

Technological networks had the pleasure of speaking with Laura Heitman, Professor of Molecular Pharmacology in the Division of Drug Discovery and Safety at the Leiden Academic Center for Drug Research (LACDR), Leiden University, to learn more about his research focused on drug-target kinetics. Heitman explains why it’s important to determine how long a drug stays bound to its target, how you can assess a drug’s target binding kinetics, and how kinetic computer studies are helping advance the field.

Laura Lansdowne (LL): Can you tell us about your work focused on understanding and improving drug-receptor interactions?

Laura Heitman (LH)
: In general, my group’s research focuses on the theme “new receptor concepts to target membrane proteins”With the ultimate goal of improving the effectiveness of drugs. I selected membrane-bound proteins, such as G protein coupled receptors (GPCRs), because many drugs work through them and play a central role in the disease. Note that the concepts I am working on are in principle “disease independent” and can be applied to many targets and disease areas.

At the start of my term in January 2009, one of these concepts, namely “drug-target residence time” or “drug-target binding kinetics” had not received much attention, if any at all. all. Since then, it has been slowly realized that the time a drug remains bound to its target may be more important than affinity, in terms of the effect in the patient. Other articles are being published and describe the importance of optimizing the binding kinetics of a drug. However, few still report on this new parameter as a eventual tool, that is, to design compounds with optimal kinetics, rather than “stumbling” on a compound with an interesting kinetic profile. Over the past few years, my group has developed several strong and accessible kinetic tests and
started to publish this data.

we were able to show for the first time that the binding kinetics of a drug on its target can be adjusted by a medicinal chemistry approach, alongside their affinity. This could have great clinical value, as retrospective analysis proves that some marketed drugs have clinical efficacy due to long target residence time. For example, using one of our in-house designed and synthesized products long stay (RT) CCR2 antagonists, we have shown that high receptor occupancy in a mouse model of atherosclerosis is the key to high efficacy. In particular, this high (or extended) occupation of the receptors leads to what is called insurmountable antagonism, i.e. antagonists which cannot be disturbed / thwarted by high local concentrations of the endogenous receptor agonist which is often causative of the disease state. Like a logic extension to the “long” target residence time, my group is currently also working on covalent ligands. As these molecules remain bound to their target ad infinitum (limited by the life cycle of the protein), the antagonists will be insurmountable.

LL: How to characterize the binding kinetics of a drug to its target?

This can be done quantitatively and qualitatively depending on the method used. We tend to use radioligand binding assays to qualitatively assess the target binding kinetics of a drug. This can be done directly by radiolabelling or fluorescing the drug of interest, or indirectly by using a competitive association assay where a reference labeled ligand is used which then competes with an unlabeled ligand of interest. . In either case, analyzing the data by nonlinear regression models will give you the kinetic rate (kdisabled and kat) values.

With regard to the quantitative analysis, one can consider using wash assays where resistance to washout of the bond or some functional effect can be observed. In addition, in functional testing one can also assess the level of “insurmountability” of an antagonist, which is essentially a phenomenon that occurs when an antagonist occupies the target for an extended period of time, resulting in damping of the target. the maximum agonist response in this functional system. .

LL: Is there one experimental technique that you think has had the most impact?

The introduction of “surface plasmon resonance” technology has really helped generate kinetic parameters in early drug discovery. Although some developments are underway, this technique is still not readily available or easily compatible with membrane-bound proteins.

LL: Why are the association and dissociation kinetics of a target-ligand complex so important?

Despite efforts (and successes) to find selective, high affinity drug candidates, attrition rates in clinical trials are disappointing. New concepts such as drug-target binding kinetics are considered increasingly important for in vivo efficiency and safety. This is most likely true because the dynamic flow and metabolism in the human body often prevent drug molecules from reaching equilibrium conditions that are otherwise easily achieved in the test tube (i.e. that equilibrium parameters are still the norm in early drug discovery). In addition, in a disease state often different conditions occur at the target site, i.e. increased levels of endogenous agonist, as mentioned above. The kinetic behavior of the compounds (speed of association with the target and with metabolic enzymes, dissociation of the target, etc.) could indeed be the guiding principle to obtain a desired and lasting effect. in vivo. Therefore, it is important to better understand the drug-target interaction that is required and to optimize it at the molecular level. in vitro. Thus, offering the prospect of better chances for kinetically optimized drug candidates in later phases of the drug development process.

LL: How do advances in computer models influence our ability to explore binding kinetics?

It is not my area of ​​expertise, but I would say that slowly more and more progress is being made in the field of kinetic computational studies. There are two computational techniques that can help understand and optimize drug-target binding kinetics: molecular dynamics (MD) and machine learning (ML). For both, ligand-protein structures are required, along with computational power (MD) and kinetic data (ML). Depending on the type of protein (i.e., membrane bound or cytosolic), structural data is limited, and kinetic data is currently also still scarce due to its underestimation. Once the limitations are lifted, these techniques can be used to visualize the molecular mode of target interaction, dissociation and possibly even association (MD), and aid in the prediction of binding kinetics for hit optimization. -lead (ML).

Laura Heitman spoke to Laura Elizabeth Lansdowne, editor-in-chief of Technology Networks.

Intergenerational report highlights the need to give community pharmacists a full scope of practice

The 2021 Intergenerational Report (IGR) presents a sobering long-term economic and fiscal outlook for Australia as we try to weather the COVID-19 pandemic, said National President of the Pharmacy Guild of Australia, Trent Twomey.

Adjunct Professor Twomey said economic growth will not be as strong over the next 40 years as in the past due to slowing population growth and aging.

“The aging of the population translates into reduced participation in the labor market, while productivity, which has been the traditional engine of prosperity, will have to pick up to compensate for the lack of population growth and participation” , said e.

“The federal budget will remain in deficit until 2060-2061 and federal health spending will continue to increase as a percentage of GDP, from 4.1% in 2018-19 to 6.2% in 2060-2061.

“Although spending projections for the Pharmaceutical Benefits Scheme (PBS) are stable, the unaffordability of drugs leading to drug nonadherence, especially for people with chronic conditions, requires further reform of co-payments from the government. PBS.

“Technological change and income growth will partly drive health care spending while – as the population ages – there will be an increased demand for health services. “

The IGR has recognized that all levels of government have a role to play in boosting productivity by ensuring diversity, choice and responsiveness in the delivery of government services.

“The way that all governments can address the challenges of IGR related to pressure on the health system, productivity and participation in general, is for every jurisdiction across Australia to unleash the skills of professionals. most trusted health care providers – community pharmacists.

“It is both immediately to administer COVID-19 vaccines but also in the medium and long term thanks to a regulatory reform to allow dispensing pharmacists to exercise fully.

“The productivity of the healthcare sector should be maximized by ensuring that all healthcare professionals work across their scope of practice.

“Community pharmacists are not only a highly skilled profession, but are the most easily accessible, located in all parts of Australia and often operating for extended hours, including evenings, weekends and holidays.

“Used across its scope of practice, community pharmacy can increase the productivity of the health sector and provide quality primary health care in a cost-effective manner.

“Scope of practice involves many functions for which pharmacists are trained, and pharmacists can be used more effectively to support people in self-management of their health problems, administration and review of medications, management and continuation of treatment for long-term health problems. as well as the ordering and interpretation of laboratory tests.

“Reforming policies and regulations at all levels of government to enable scope of practice will ensure savings materialize for the health system. “

Another important area that the IGR highlighted was the challenges associated with caring for the elderly.

Adjunct Professor Twomey said the IGR has recognized reforms and funding for elderly care announced under the recent federal government, but also that the number of older Australians in need of elderly care services will increase over time. over the next 40 years.

“Until now, the challenges of senior care have been neglected, so with careful government investment, community pharmacists can be part of the solution,” he said.

“This includes medication management and adherence programs for older Australians wherever they live, as well as during care transitions.

“Overall, the IGR clearly shows the long-term challenges associated with an aging population in the context of the immediate challenge of the COVID-19 pandemic.

“Part of the solution and the response to these challenges is to engage and use the community pharmacy network to its full potential, for the betterment of the people of Australia. “

Tree seedlings available to order from the NC Forest Service from Thursday

As the United States intensified its efforts during World War II in the early 1940s, Fort Bragg became the largest military post in the country, accommodating 60,000 troops.

But lesser-known military training was taking place about 40 miles southwest of Fort Bragg, in what is now Laurinburg-Maxton Airport. As many as 10,000 soldiers were stationed at the site, which has become the largest glider pilot training base in the world, according to the history of the airport.

At the time, the Laurinburg-Maxton military airbase in the county of Scotland was functioning much like a town, said Seth Hatchell, deputy airport manager.

“They had a little cinema here,” he said. “They had their own chapel which still exists today.”

About 80 years later, the airport still hosts military personnel, including the US Army Golden Knights, who regularly parachute to the site.

But now executives are hoping that the airport and its large industrial park which is already home to a dozen companies will attract more companies that need to land and host jets, as well as more private pilots who are in need of jets. fly for fun.

With improvements and expansion, the idea is for the airport and industrial park to serve as a commercial hub and economic engine for Southeastern North Carolina.

“I think we’ve all understood that the airport is an underutilized resource for our region,” said Guy McCook, Chairman of the Airport Commission.

With the help of State Senator Tom McInnis, a Republican who represents the counties of Anson, Moore, Richland and Scotland, the airport is expected to receive $ 8 million in funding from the state to expand one of its three runways from 6,500 to 8,500 feet.

This will make it the eighth longest runway in the state, with the ability to handle any aircraft, Hatchell said.

Laurinburg-Maxton will only be the fifth airport in the state with a runway of this length, Hatchell added.


In the 1990s, North Carolina rulers envisioned a multimodal manufacturing and distribution center that would spur economic development and help bring the state into the 21st century.

The result was the North Carolina Global TransPark, a 2,500 acre business park in the town of Kinston in Lenoir County.

Laurinburg-Maxton Airport was the finalist for the project, McCook said.

“At the time, we felt like this decision was made more based on policy than facilities and location,” he said. “Having said that, we think we are well positioned to be a large industrial park. “

Airport officials are working with the state’s Commerce Department to create a strategic plan that could be completed by the end of the year. Hatchell said the Global TransPark could serve as a guide.

“I haven’t had the chance to go visit it, but it’s something that’s been on my wish list for a few months now,” he said. “Especially with our industrial park and see, okay, what worked for them and what didn’t work for them, and how can we improve? “

On its website, the Global TransPark indicates that its “sites and buildings are fully equipped and ready to work. From utility planning to advanced telecommunications connectivity, everything you need is in place to get you up and running. “

Hatchell said Laurinburg-Maxton Airport also has infrastructure, including fiber optics, water and sewage.


After the end of World War II in 1945, the United States Department of Defense gave the base to the town of Maxton and the town of Laurinburg to serve as a general aviation airport.

The donation also came with a water treatment system, which contributes much of the airport’s finances, Hatchell said.

Aging infrastructure and deferred maintenance now need to be tackled, McCook said.

McCook, a former County Commissioner of Scotland, was appointed to serve on the airport’s board of directors, which was restructured as part of a Senate bill introduced by McInnis in 2019. The Commission of Laurinburg-Maxton Airport became the South East Regional Airport Authority.

The idea, say the leaders, is to think bigger than the county of Scotland. This includes the airport’s efforts to become a designated foreign trade zone, which may simplify some customs procedures.

The airport still owns about 3,000 acres, Hatchell said, and about 1,000 acres are “prime property.”

“We just want to be the best airport possible, and we want to try to find as many resources – financial and otherwise – to try to become something that can be a great asset for communities,” said McCook.

Hatchell, 23, said he was excited about the future of the airport. After growing up in Scotland County, he attended Liberty University in Virginia, where he studied aviation.

He never dreamed that he could come back and pursue a career. Now, he said, he’s excited to be a part of something that could spur economic development.

“Being my hometown gives me even more reason to do this, to go the extra mile to bring industry and growth to the county of Scotland,” he said. “And being from here, you kind of wear it with a badge of honor.”

The mock budget process was really disappointing

This is my fourth update to the citizens of the 111th arrondissement, as a representative of your state.

There is so much to cover, as the spring legislative session ended on May 31. I delayed writing this report because I wanted to discuss the comprehensive energy legislation that I expected to vote on, but this legislation was unsuccessful. We closed the session on May 31 without energy legislation, then we were called back to Springfield on June 16, hoping to vote on an energy package, but again no progress was made.

At the moment, I don’t know when or if we’ll be called back to vote on energy issues such as the Clean Energy Jobs Act, the nuclear grants requested to keep open two nuclear power plants in northern Illinois, the Solar Cliff and other related matters. Some of these questions are urgent and need to be dealt with very quickly.

In my last monthly update, I warned that the last days of May are traditionally when controversial bills are passed without the support of Republicans, and sadly this session was no different. More specifically, the finance bill for fiscal year 2022 was tabled on May 31, was the subject of several amendments throughout the day, was called to be heard in the room at 11:35 p.m., then was put to the vote at 11:55 p.m.

Republicans were allowed to ask questions of a speaker and the debate ended quickly.

There is no way that members of either party can really read and review a document over 3,000 pages long in such a short time, and I voted no. This is a $ 42.3 billion budget that includes an undeserved pay rise for lawmakers and unnecessarily doubles the budgets of our offices. While some social service organizations may receive increases, others cannot.

The mock budget process was truly a bummer and is an embarrassment for a CPA like me to witness. No business, nonprofit, and certainly no local government could or should budget in this way.

Another question of great importance which was quickly voted on and promulgated by the governor is that of legislative maps. Every ten years, maps must be redrawn based on census information. Although census data is not yet available, the Democratic-controlled legislature has passed its cards for the state legislature, the Illinois Supreme Court and the Cook County Board of Review.

These maps were apparently drawn using data from the American Community Survey, election data, and various other unknown sources. Once the cards were enacted by Governor JB Pritzker, lawsuits were swiftly filed to challenge these cards and, therefore, it is expected that more results will be achieved on these cards.

An election-related bill that extends the primary date from 2022 to June instead of March, so it’s time to settle all of this through the court process.

One of the bipartisan bills that has been passed by the House and Senate that is awaiting the governor’s signature concerns inflated trailer plate fees. SB58 finally cuts the trailer plate fee from $ 118 to $ 36 (but not at the original price of $ 18). I believe this is only resolved because of the outcry from people across the state who have pushed this back, loudly and often, and really raised their voices, and I thank you for that.

One of the bills I’m most proud to work on in this session is HB1975, which is a comprehensive bill aimed at preventing sexual abuse of students by school staff. The bill was passed unanimously by the House, but unfortunately was not called for a committee hearing in the Senate.

It could still be voted on in the fall veto session and I am working with supporters of the bill to bring attention to the bill and to contact senators. The crime of student sexual abuse is still happening, and we will not stop fighting for our students.

I am pleased to report that the road naming resolutions for two roads in Godfrey have been passed by both the House and the Senate. The roads will be named after Captain Jake Ringering and Eldon “Twirp” Williams. Special thanks to Godfrey Mayor Mike McCormick for leading this effort.

In addition, two good government bills that I sponsored as chief were passed unanimously and will be submitted to the governor for signature. SB85 requires fire districts to use tenders for leases over $ 20,000, and SB2172 gives additional time to implement a required pharmacy technical training program statewide.

In preparation for the summer, I am back in the district and visiting local nonprofits, businesses, farms and government agencies. We continue to work with voters on a wide variety of issues, including FOID and CCL card issues, unemployment issues, state agency issues and more.

We are always happy to help in any way. Please feel free to call my office at 618-433-8046 if we can assist you.

State Representative Amy Elik, R-Fosterburg, represents Illinois’ 111th Legislative District.

Chula enters medical cannabis and expands product line

“Cannabis” is a valuable cash crop with immense benefits in medicine, health, nutrition and beauty. As soon as the Thai government gave the green light, Chulalongkorn was ready to partner with the private sector and government agencies to accelerate research and development for a wide assortment of cannabis products.

Since the Thai government legalized medical cannabis, many high potential higher education institutions have moved forward with research. Chulalongkorn University established the “Chula Cannabis and its Natural Substances (Chula CANS) Research cluster with expert professors from various fields, as well as the first and only drug dependence research center in the country that is certified by the World Health Organization (WHO) Collaborating Center for Drug Addiction Research and Training.

According to Asst. Teacher. Dr. Rungpetch Sakulbumrungsilp, Dean of the Faculty of Pharmaceutical Sciences, Chulalongkorn University, unlike the present where many facets and aspects of cannabis are studied in addition to the work of Chula CANS, very little research on cannabis has been carried out over the years. 10 years preceding its legalization. There are also many joint research projects, for example, the faculties of pharmaceutical sciences and dentistry, which are jointly developing cannabis in dental medicines such as topical anti-inflammatory ointment for canker sores. Other faculties are interested in the treatment of neurological diseases such as Parkinson’s disease, epilepsy, etc.

Ass. Teacher. Dr Rungpetch Sakulbumrungsilp
Dean of the Faculty of Pharmaceutical Sciences, Chulalongkorn University

Find investment partners and move forward

Companies such as Bloom Medica Co., Ltd. have invested with Chulalongkorn through the Faculty of Pharmaceutical Sciences and the Faculty of Science to jointly develop quality cannabis species to produce extracts and use them in medicine, health supplements and care products skin. For starters, studies are underway on the production of an extract active against the Thai cannabis genus coronavirus that contains a higher psychoactive compound than foreign varieties. The cannabis plantation project is located in Kui Buri District, Prachuap Khiri Khan Province.

More recently, the Drug Dependence Research Center, College of Public Health Sciences, in collaboration with Thonburi Healthcare Group Public Company Limited, developed a variety of cannabis suitable for medical use. In addition, support was also provided for the establishment of a medical grade cannabis extraction plant with full upstream and downstream production and distribution technology.

A strategy to support Thai agriculture

A pilot greenhouse cannabis cultivation project is being carried out outside the Chula campus in Saraburi province by the Drug Dependence Research Center, College of Public Health Sciences, to improve the research and propagation of medical cannabis from quality. Work on the development of breeds adapted to the local climate and to the classification of different species in Thailand is also underway.

Professor Chitlada Areesantichai, vice-dean of the College of Public Health Sciences and director of the Drug Addiction Research Center explained that the planting of more than one rai (1,600 square meters) on Chula land is operated with meticulous quality control. We use seeds that have been cleared from legal proceedings by the criminal court and grown organically without chemicals. We only use organic fertilizers and unique organic insect repellents developed by the Center.

Dr. Chitlada Areesantichai, Associate Dean of the College of Public Health Sciences and Director of the Center for Drug Dependence Research
Teacher. Dr. Chitlada Areesantichai,
Assistant Dean of the College of Public Health Sciences,
and Director of the Center for Research on Addiction

“The main objective of the pilot greenhouse is to produce the highest yield of quality cannabis extracts. We divide the project into 3 systems: 1) Internal culture with humidity, temperature and external light control; 2) Semi-closed culture or in greenhouse with screens to avoid insects, ventilation and exposure to natural light; and finally, an open or outdoor system with video surveillance for security, ”said Professor Dr Chitlada.

A pilot greenhouse cannabis project, Chula Saraburi campus
A pilot greenhouse cannabis project, Chula Saraburi campus

In addition, the project is also organizing a one-day training for local farmers to experiment with organic farming techniques starting with the first group at the end of April 2021.

Cannabis ice cream – health food

The use of cannabis in cooking has been around for a long time, but the question of the right amount that will not pose a health risk is a subject of study and research. The Food and Drug Administration (FDA) funded the Drug Dependence Research Center to study the safe use of cannabis in food ingredients.

Chula’s Faculty of Pharmaceutical Sciences expanded this research to create “cannabis ice cream” using the leaves of the Charlotte’s Angel CBD variant that remain from the research cluster project.

Assoc.  Teacher.  Dr. Sornkanok Vimolmangkang, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Chulalongkorn University

Assoc. Teacher. Dr Sornkanok Vimolmangkang

Department of Pharmacognosy and Pharmaceutical Botany,
Faculty of Pharmaceutical Sciences

Assoc. Professor Dr. Sornkanok Vimolmangkang, Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, and Chairman of the Chula CANS Research Pole said that cannabis ice cream is a model of cannabis-derived products that has quality control standardized different from edibles containing cannabis on the general market.

“Chula’s cannabis ice cream comes in 3 flavors: pure cannabis; hojicha green tea cannabis; and cannabis with matcha tea. Hojicha and matcha green tea already smell like cannabis, so when mixed together they make a perfect blend, ”said Assoc. Teacher. Dr Sornkanok. The ice cream making process begins with the fermentation of raw materials grown with high quality control. The secret lies in the special process of drying the leaves that retains the unique aroma of cannabis, before crushing it into a powder and mixing it with ice cream.

Dr Varalee Yodsurang, Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University
Dr Varalee Yodsurang,
Department of Pharmacology and Physiology,
Faculty of Pharmaceutical Sciences

Dr Varalee Yodsurang, Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, added that cannabis ice cream has the controlled level of 0.2% THC as prescribed by the Ministry of Public Health. In addition, Chula has also limited the age of buyers to at least 18, and people with certain underlying illnesses are advised not to consume the ice cream.

cannabis ice cream

Cannabis ice cream

The first batch, a limited number of 500 cups of cannabis ice cream, is available for sale at Healthplatz By Double T, Chula Pharmaceutical Sciences Alumni Association. In the future, Chula Pharmaceutical Sciences will also offer an ice cream making course to the interested public.

Cannabis in art – Art toys “HAYAK”

For the first time in contemporary art circles, cannabis waste has been turned into artistic toys called giant “HAYAK” figures. Available from the collection in 13 designs and 13 colors, HAYAK toys are a creation of a former student of the Faculty of Pharmaceutical Sciences.

Worachai Matkit, alumnus of Chula Pharmaceutical Sciences
Worachai Matkit, alumnus of Chula Pharmaceutical Sciences

“The cannabis waste used to create the artistic toys comes from marijuana confiscated and rejected by the Office of the Narcotics Control Board (ONCB) that has already been extracted and then tested for binding property, separated by texture (coarse vs fine), before being turned into toys, ”said Worachai Matkit, a Chula Pharmaceutical Sciences alumnus, on behalf of Thai Together Co., Ltd.

Artistic “HAYAK” toys are available at the Chula Pharmaceutical Sciences Alumni Association as Japanese “Gachapon” balls, or can be purchased from souvenir vending machines under the name “GANJAPONG HAYAK X CHULA CANS”. For more details, visit the Facebook page: HAYAK.

Democrats try to bring dental, vision and hearing care into Medicare

WASHINGTON – Many people of working age assume Medicare covers just about any type of health care an older person may need.

This is not the case.

Some of the most significant gaps relate to dental, vision and hearing services. Medicare does not cover dental cleanings or root canals. It does not cover everyday eyeglasses and contact lenses. It does not cover hearing aids.

Now Democrats are trying to make these benefits a standard feature of Medicare under massive, multifaceted legislation expected later this year to advance President Joe Biden’s ambitious national agenda.

Many see the expansion of the program as late. But that doesn’t mean it will be easy.

What are the prospects?

Senator Bernie Sanders, I-Vt., And other progressives are leading the campaign for dental, vision and hearing coverage. Their goal is to provide a comprehensive benefit accessible to as many Medicare beneficiaries as possible without delays such as an extended start-up period.

But adding more benefits to Medicare is expensive, and the idea will have to compete with other priorities on the Democrats’ healthcare wishlist.

Republicans are expected to unite against sweeping legislation on the Biden agenda in which Medicare benefits would be merged. Democrats are expected to pass the bill under special budget rules that allow a simple majority to clear the Senate.

“It’s far too early to cripple the odds,” said Tricia Neuman, health insurance expert with the Kaiser Family Foundation, a non-partisan organization.

How would the new benefits be delivered?

The simplest approach seems to involve making dental, vision, and hearing coverage a component of Medicare Part B, which pays for outpatient care.

Part B is voluntary, but the vast majority of the over 60 million Medicare beneficiaries enroll. There is a premium, and most people now pay $ 148.50 per month. While it’s not cheap, it’s actually considered a good deal as taxpayers cover 75 percent of the overall cost of insurance. One would expect premiums to rise with richer benefits, but the cost would be broadly distributed.

Also, most people with private Medicare Advantage plans now have some level of dental coverage, but this can vary widely. If dental, visual, and hearing benefits were standard in Part B, Medicare Advantage plans should provide them as well.

What types of services would be covered?

Although the details take a while to be worked out, full dental coverage would include regular preventative care such as cleanings and x-rays, minor work such as fillings, and major work including root canals, crowns and crowns. dental prosthesis.

Visual coverage would include glasses and contacts, as well as necessary examinations and adjustments. Hearing coverage would include hearing aids and their maintenance, as well as audiology services.

How much would it all cost?

Again, this is unclear as key details such as the scope of benefits and cost-sharing by Medicare beneficiaries have not been determined.

But a 2019 bill from House Speaker Nancy Pelosi, D-Calif., Cost nearly $ 360 billion over 10 years.

Of that, $ 238 billion would have paid for dental care, $ 30 billion would have paid for vision care and $ 89 billion would have paid for hearing services, the Congressional Budget Office estimated.

The extended coverage was part of broader legislation that would have allowed Medicare to negotiate the prices of prescription drugs. Part of the savings in drug costs would have been put back into the program.

Pelosi’s bill passed the House but went nowhere in the Senate. Democrats still use his approach as a model.

What is the need?

Dental care, vision and hearing are considered integral parts of good health.

An older person with hearing problems who cannot afford hearing aids may find themselves in a deeper and deeper state of isolation which can exacerbate depression. Dental infections can spread through the bloodstream to other parts of the body.

But a 2019 Kaiser Foundation report found that nearly 2 in 3 Medicare beneficiaries did not have dental coverage, and nearly half had not seen a dentist in the past year. About 1 in 7 people have lost all of their teeth.

Black and Hispanic registrants were much less likely to have seen a dentist in the past year.

“This is obviously a big, yawning hole in the Medicare program,” said David Certner, legislative director of AARP.

Why does Medicare not cover dental, vision and hearing care?

Experts say the reason probably dates back to 1965, when the program was created. It was modeled on the types of private health insurance that were then most commonly available. And these were built around hospitalization and doctor visits.

Another big gap in coverage – prescription drugs at retail pharmacies – was not closed until 2003.

What else is not covered by Medicare?

Long term care.

Could Laurinburg-Maxton Airport Become a Regional Business Center in North Carolina? Leaders hope so

Shown is the terminal at Laurinburg-Maxton Airport in the County of Scotland.

Courtesy photo | Seth Hatchell

As the United States intensified its efforts during World War II in the early 1940s, Fort Bragg became the largest military post in the country, accommodating 60,000 troops.

But lesser-known military training was taking place about 40 miles southwest of Fort Bragg, in what is now Laurinburg-Maxton Airport. As many as 10,000 soldiers were stationed at the site, which has become the largest glider pilot training base in the world, according to the history of the airport.

At the time, the Laurinburg-Maxton military airbase in the county of Scotland was functioning much like a town, said Seth Hatchell, deputy airport manager.

“They had a little cinema here,” he said. “They had their own chapel which still exists today.”

About 80 years later, the airport still hosts military personnel, including the US Army Golden Knights, who regularly parachute to the site.

But now executives are hoping that the airport and its large industrial park which is already home to a dozen companies will attract more companies that need to land and host jets, as well as more private pilots who are in need of jets. fly for fun.

With improvements and expansion, the idea is for the airport and industrial park to serve as a commercial hub and economic engine for Southeastern North Carolina.

“I think we’ve all understood that the airport is an underutilized resource for our region,” said Guy McCook, Chairman of the Airport Commission.

With the help of State Senator Tom McInnis, a Republican who represents the counties of Anson, Moore, Richland and Scotland, the airport is expected to receive $ 8 million in funding from the state to expand one of its three runways from 6,500 to 8,500 feet.

This will make it the eighth longest runway in the state, with the ability to handle any aircraft, Hatchell said.

Laurinburg-Maxton will only be the fifth airport in the state with a runway of this length, Hatchell added.


In the 1990s, North Carolina rulers envisioned a multimodal manufacturing and distribution center that would spur economic development and help bring the state into the 21st century.

The result was the North Carolina Global TransPark, a 2,500 acre business park in the town of Kinston in Lenoir County.

Laurinburg-Maxton Airport was the finalist for the project, McCook said.

“At the time, we felt like this decision was made more based on policy than facilities and location,” he said. “Having said that, we think we are well positioned to be a large industrial park. “

Airport officials are working with the state’s Commerce Department to create a strategic plan that could be completed by the end of the year. Hatchell said the Global TransPark could serve as a guide.

“I haven’t had the chance to go visit it, but it’s something that’s been on my wish list for a few months now,” he said. “Especially with our industrial park and see, okay, what worked for them and what didn’t work for them, and how can we improve? “

On its website, the Global TransPark indicates that its “sites and buildings are fully equipped and ready to work. From utility planning to advanced telecommunications connectivity, everything you need is in place to get you up and running. “

Hatchell said Laurinburg-Maxton Airport also has infrastructure, including fiber optics, water and sewage.


After the end of World War II in 1945, the United States Department of Defense gave the base to the town of Maxton and the town of Laurinburg to serve as a general aviation airport.

The donation also came with a water treatment system, which contributes much of the airport’s finances, Hatchell said.

Aging infrastructure and deferred maintenance now need to be tackled, McCook said.

McCook, a former County Commissioner of Scotland, was appointed to serve on the airport’s board of directors, which was restructured as part of a Senate bill introduced by McInnis in 2019. The Commission of Laurinburg-Maxton Airport became the South East Regional Airport Authority.

The idea, say the leaders, is to think bigger than the county of Scotland. This includes the airport’s efforts to become a designated foreign trade zone, which may simplify some customs procedures.

The airport still owns about 3,000 acres, Hatchell said, and about 1,000 acres are “prime property.”

“We just want to be the best airport possible, and we want to try to find as many resources – financial and otherwise – to try to become something that can be a great asset for communities,” said McCook.

Hatchell, 23, said he was excited about the future of the airport. After growing up in Scotland County, he attended Liberty University in Virginia, where he studied aviation.

He never dreamed that he could come back and pursue a career. Now, he said, he’s excited to be a part of something that could spur economic development.

“Being my hometown gives me even more reason to do this, to go the extra mile to bring industry and growth to the county of Scotland,” he said. “And being from here, you kind of wear it with a badge of honor.”

The Border Belt Independent is a non-profit online newsroom that focuses on the issues and challenges affecting the counties of Bladen, Columbus, Robeson and Scotland.

Foods for sun protection to incorporate into your diet this summer

One of the greatest weapons in the dermatological arsenal, sunscreen is a crucial step in any skin care routine. Its benefits are both functional and cosmetic. According to the Skin Cancer Foundation, not only does regular application of sunscreen reduce the risk of skin cancers such as basal cell carcinoma and melanoma, it also prevents the development of features of aging such as liver spots, fine lines and wrinkles. But applying Coppertone isn’t the only way to avoid sun damage. Surprisingly, your diet also plays an important role in skin health. Essentially, eating to maintain your youthful glow “is about staying well hydrated … and eating healthy, mostly whole foods.” [and] mostly plant-based diet rather than trying to drink and supplement your path to health, ”Dr. Doris Day, MD, certified dermatologist and clinical associate professor of dermatology at the University’s Langone Medical Center, told TZR from New York.

Dr. Day’s peer, Dr. Rajani Katta, MD, a certified dermatologist and former professor of dermatology at Baylor College of Medicine, breaks down the science behind this claim. Foods that contain antioxidants, substances that include vitamins, minerals, and phytonutrients, can offset the harmful effects of UV rays by strengthening your skin’s natural defenses, Dr. Katta tells TZR. “[T]he skin is constantly … exposed to threats, be it UV radiation, pollution, or body-specific processes, so there are all these complex systems out there designed to neutralize those threats within a day ” , explains Dr. Katta. “And one of those systems is that we actually have a lot of antioxidants that are right in the layers of our skin all the time.”


When the sun’s rays hit your skin, they trigger the production of free radicals, highly reactive molecules that have one or more unpaired electrons. Once they reach critical mass, free radicals catalyze chemical chain reactions that can cause premature aging and diseases such as cancer, heart disease and arthritis, according to a 2010 article published in the journal peer-reviewed scientist. Pharmacognosy Reviews. In the process, they also promote inflammation, a systemic immune response that can have similar negative effects, says Dr. Katta.

Fortunately, antioxidants specialize in preventing free radicals from wreaking havoc on cells. While your body produces the substances naturally, eating foods rich in them replenishes its existing reserves. That said, what foods are these? Fruits and vegetables are always a safe bet, says Dr. Katta. They, along with herbs and spices, “are among the most powerful sources of antioxidants,” she says. Take tomatoes, for example. A 2001 study found that people who consumed 40 grams of tomato paste every day for 10 weeks were more resistant to late sunburn than they were at the beginning, thanks to increased serum levels. of lycopene phytonutrient. In turmeric, curcumin confers similar benefits; in green tea, catechins; in raspberries, ellagic acid; in red grapes, resveratrol.

So, we should incorporate more of all of the above in our diet. What else? Beyond that, “I’m really thinking of… foods high in vitamin C” like citrus fruits and red peppers “and foods high in vitamin E” like almonds and walnuts, says Dr. Katta. For his part, Dr. Day recommends eating seasonal produce.

“So in the fall, we have tomatoes, we have pomegranates, we have squash. These are amazing for the skin, ”she says. “They contain a whole range of antioxidants, from vitamin C to vitamin A and potassium. [and] magnesium. All of these are important. “

The classic Mediterranean diet will also provide you with all the antioxidants you need, says Dr. Day. So named because it emphasizes ingredients commonly found in traditional regional dishes; the diet is high in tomatoes, olive oil, oily fish, nuts, and seeds and light in sugary drinks, refined carbohydrates, saturated fat, and red meats, according to the American Heart Association. Several of these have been linked to an increased risk of one or more types of cancer.

“[E]even the occasional glass of red wine was thrown into it as potentially useful. It’s a bit of the most uncertain because I don’t know if you’re really getting enough antioxidants from red wine, but, you know, whatever. Have fun while you’re at it, ”says Dr Day, laughing.

However, eating foods rich in antioxidants is no substitute for wearing sunscreen every day. Eating raspberries and red peppers cannot immunize your skin against the negative consequences of exposure to UV rays.

“So you can’t replace sunscreen with supplements or foods, but you can increase the benefits,” says Dr. Day. “[E]Even if you protect yourself well from the sun, you still take damage, for example, there is no way to avoid it. But you can help protect yourself from the damage and even reverse some of it with the right supplements and the right diet. Getting enough sleep, she says, is also necessary for healthy skin.

With the hot vax summer in full swing, you’ll want to look – and, of course, feel – at your best. Vanity is a powerful motive, after all. With that in mind, heed the advice of Dr Day and Dr Katta. Make salads. Grill fish. Brew green tea. And in between, don’t forget to apply sunscreen.

Studies and referenced sources:

Skin Cancer Foundation. (January 10, 2019,). Photoaging: What you should know about the other type of aging. https://www.skincancer.org/blog/photoaging-what-you-need-to-know/

Skin Cancer Foundation. (Updated January 13, 2021). Skin cancer facts and statistics. https://www.skincancer.org/skin-cancer-information/skin-cancer-facts/#aging

Stahl, W., et al. (2001, May). Edible tomato paste protects against erythema induced by ultraviolet light in humans. The Journal of Nutrition. https://doi.org/10.1093/jn/131.5.1449

The editorial staff of the American Heart Association. (Reviewed in 2020, January 9). What is the Mediterranean diet? American Heart Association. https://www.heart.org/en/healthy-living/healthy-eating/eat-smart/nutrition-basics/mediterranean-diet

Lobo, V., et al. (2010, October). Free radicals, antioxidants and functional foods: impact on human health. Pharmacognosy reviews, https://doi.org/10.4103/0973-7847.70902

Cheribundi launches immunity boosting drink

Greenwich, Connecticut. – Cheribundi, the leader in high-performance natural drinks specializing in tart cherry juice, announces the launch of its brand new drink: Cheribundi Immunity. The product is the first drink on the market to combine tart cherry juice with echinacea and B vitamins, three natural immune system boosters that together provide a simple yet powerful solution for athletes of all skill levels who want to maximize their performance and minimize bad days, while supporting athletic recovery, inflammation reduction and sleep.

“Now more than ever, while recovery after exercise – the last mile of performance – isn’t intrinsically linked to immune health, it misses the mark,” said Marcel Bens, CEO of Cheribundi and Managing Partner and COO of Emil Capital Partners. “And while tart cherry juice already has immune support benefits, we wanted to do even more, so we created a multi-functional solution that people could easily incorporate into their active lifestyles to further support their most valuable asset.” : their health. “

Numerous independent studies published in renowned medical journals over the past 15 years have proven the health and fitness benefits of tart cherry juice, including its ability to accelerate recovery and repair of muscle tissue, to minimize muscle damage and muscle pain induced by exercise; decrease inflammation, inflammation-related conditions and upper respiratory tract infections; prevents joint pain and gout, and significantly improves the quality and duration of sleep.

In May, Cheribundi commissioned an independent study in partnership with Pebble Strategy to find out what motivates the everyday athlete and understand their knowledge of tart cherry juice. He found that 63 percent of everyday athletes are more interested in drinking it for its immune properties, confirming market demand for the product.

The following research results highlight how the three key ingredients in Cheribundi Immunity support immune health:

  • Tart cherries have antimicrobial properties, which can target pathogenic bacteria and the common cold (The Journal of Nutritional Biochemistry, 2018)
  • Tart cherries are rich in antioxidants, such as anthocyanins and catechins, which fight inflammation (US National Library of Medicine, 2018)
  • Tart cherries are rich in vitamin A, which is essential for immune function (US National Library of Medicine, 2018)
  • Echinacea has been shown to improve immunity, blood sugar, anxiety, inflammation, and skin health. It may even have anticancer properties (Pharmacognosy Reviews, 2015)
  • Echinacea has been shown to significantly reduce inflammation, chronic pain, and swelling, and may help you recover from illness faster (Phytomedicine, 1994)
  • Vitamin B6 + B12 helps support a healthy immune system by supporting cellular health, red blood cells, energy levels, and cardiovascular health (Harvard)

In addition to Cheribundi Immunity, Cheribundi offers seven other high-performance, recovery-focused natural drinks that harness the power of tart cherry juice, including (per 8 oz serving):

  • PURE: 60 tart cherries
  • PROTEIN: 45 tart cherries, whey protein and B vitamin complex
  • HYDRO: 40 tart cherries, 33% coconut water and B vitamin complex
  • RESET: 40 tart cherries, valerian root and lemon balm
  • ORIGINAL: 50 tart cherries, naturally sweetened with apple juice
  • DARK: 40 tart cherries, black cherries, naturally sweetened with apple juice
  • LIGHT: 40 tart cherries, naturally sweetened with stevia leaf

Cheribundi is available at nearly 50,000 outlets in the United States and can also be found online at Kroger, Publix, Amazon, Walmart, and Cheribundi.com. Cheribundi Immunity costs $ 27 for a 12-pack and is currently available on cheribundi.com. It will begin rolling out to other retailers later this summer.

About Cheribundi

Cheribundi is a natural performance drink company specializing in one of the most effective functional tools for athletic recovery: tart cherry juice. Using a proprietary filtration process developed with Cornell University, Cheribundi harnesses the incredible power of phytonutrients and antioxidants in tart cherries to create superior offerings scientifically proven to accelerate muscle recovery, relieve pain, support l immunity, reduce inflammation and improve sleep. From everyday athletes to the more than 300 professional and college sports teams who drink it regularly, Cheribundi’s mission is to prove that athletic performance can and should be natural. Cheribundi drinks are non-GMO and not based on concentrate.

For more information:

What is Thai brood virus and why does it affect bee colonies?

  • The Asian honey bee (Apis cerana), more commonly found in southern India, is affected by the Thai sac brood virus (TSBV).
  • Since the disease does not directly affect humans, research has been slow. But if the spread continues, it could lead to the extinction of the most domesticated bee species in southern India.
  • Although apiary hygiene measures and queen isolation are recommended as solutions, more research is needed to help beekeepers manage the challenge of TSBV.

Thai Sacbrood, a viral disease affecting honey bee colonies, has resurfaced in southern India. The disease, which had been dormant in the southern states for a few years, is back and is impacting the bee population in particular in the Apis cerana species. This, in turn, can have far-reaching consequences for human life which depends indirectly or directly on honey bees.

What is Thai brood virus and how does it work?

Thai brood virus (TSBV) is a variant of sac brood virus (SBV), a viral disease affecting honey bee colonies. TSBV disease was first observed in Thailand in 1976. In 1991-92, an epidemic of the virus broke out in India, resulting in the destruction of over 90 percent of the bee colonies then. existing in southern India. The disease kills bees when they are larvae, thereby reducing the population of bee colonies.

To identify diseased combs, the combs are observed for any color change. The color of the prepupae (the stage of development before the pupal stage) changes from white to yellow, then to dark brown. Other symptoms include: the presence of prepupa with pointed, raised heads in the comb cells and dead larvae that develop into fluid-filled “sac” structures. At the age of 10 days, they come off easily. Brood virus that attacks Apis mellifera is less virulent than TSBV.

Apis cerana honey bees are mainly found in southern India. Photo by Chinmaya KV.

What is the meaning of Apis cerana the bees?

Apis cerana or the Asian honey bee is one of the most domesticated honey bee species in India and it is important to understand ways to protect their population. Bees are very important for the ecosystem. Humans depend on bees directly (for honey which has antioxidant and anti-inflammatory properties) and indirectly. Bees play a crucial role in pollination. Crops produce good yields if animals and insects help them pollinate. And bees are the most dominant pollinators of fruit, vegetable and crop plants. Data shows that bees visit around 90 percent of the world’s 107 major crops. In a study published last year in Nature, scientists found evidence that melittin, a component found in bee venom, can kill cancer cells.

Apis mellifera, Apis cerana, Apis dorsata, Apis florea and Trigona are the main bee species found in India. Apis cerana is mainly found in southern India. Farmed and wild bees are responsible for the growth and quality of vegetation. Bees are crucial for food security. However, the world’s bee population is in decline. It is essential to protect them and to be prepared to face the viruses that attack their colonies.

Why do we need to study the virus?

Beekeeping is an important source of additional income for farmers and farm workers. Beekeeping has become a major occupation in southern India since the 20th century. TSBV is also believed to affect the livelihoods of many of these farmers. Nagendra Sagar, professional beekeeper and beekeeping demonstrator from Shivamogga, Karnataka, expresses concern over the spread of TSBV saying: “A few years ago we stopped beekeeping due to the outbreak of this virus in the south. from India. The migration of bees from different states could be one of the reasons for this epidemic. Now we see TSBV active again in the West Ghats bee colonies in Karnataka. “

Sagara adds: “As beekeepers, we need to better understand TSBV in order to be able to control it. Since this does not affect humans, we assume that the scientific community is ignoring the spread. There is therefore no major research underway in this area. “

It is also crucial that more scientists and researchers work on this topic, as TSBV can spread to other parts of the world and not be contained in southern India. By studying TSBV, we can be warned about upcoming viruses that could also harm bees.

Thai Sac Brood virus disease (TSBV) which attacks Indian honey bees poses a threat to Apis cerana hives.  Photo by Chinmaya KV.
Thai Sac Brood virus disease (TSBV) which attacks Indian honey bees poses a threat to beehives in Apis cerana. Photo by Chinmaya KV.

How do we protect bees from TSBV?

The most recommended method of controlling the spread of the disease is to remove the infected honeycombs that contain the dead larvae and burn them. This virus is also spread through humans, in the same way as SARS-COV2. If a person touches infected colonies and then touches healthy dishes, the virus will also spread to other dishes. It is recommended that responsible persons always wash their hands with soap before touching new cans. A recent study suggests isolating the queen bee from other worker bees in the colonies to manage the spread. However, there is no clear protocol to save honey bees from TSBV.

Karnataka Government Biodiversity Council Chairman Ananth Hegde Ashisar assures scientists will solve this problem and find a clear solution very soon. He adds: “The Karnataka Biodiversity Board is considering declaring the honey bee as a ‘state insect’, given its importance in the ecosystem. Concerning the TSBV, we regret to inform you that our scientists and agents concerned are not following it with the Government and beekeepers. We have advised the minister and relevant officials to look into the matter. “

Scientific beekeeping and virus surveillance in different bee species are essential to ensure that TSBV does not spread further.


Samarghandian, S., Farkhondeh, T., & Samini, F. (2017). Honey and health: a review of recent clinical research. Pharmacognosy research, 9(2), 121.

Koffler, S., Barbiéri, C., Ghilardi-Lopes, NP, Leocadio, JN, Albertini, B., Francoy, TM, & Saraiva, AM (2021). A buzz for sustainability and conservation: the growing potential of citizen science studies on bees. Durability, 13(2), 959.

Patel, V., Pauli, N., Biggs, E., Barbour, L. and Boruff, B. (2021). Why bees are essential for achieving sustainable development. Ambio, 50(1), 49-59.

Mohan Rao, K., Katna, S., Rana, BS & Rana, R. (2015). Thai brood and brood viruses in relation to European foulbrood of hive bees in India – a review. Beekeeping Research Journal, 54(3), 192-199.

Duffy, C., Sorolla, A., Wang, E., Golden, E., Woodward, E., Davern, K.,… & Blancafort, P. (2020). Bee venom and melittin suppress the activation of growth factor receptors in HER2 enriched and triple negative breast cancer. NPJ Precision Oncology, 4(1), 1-16.

Stindl, R., & Stindl Jr, W. (2010). Endangered honey bees: is the death of adult worker bees a consequence of short telomeres and premature aging ?. Medical hypotheses, 75(4), 387-390.

Banner image: Apis cerana the bees. Photo by Denis Anderson, CSIRO / Wikimedia Commons.

Apply for 17 technical agent positions before July 23

The National Botanical Research Institute (NBRI) has announced an online job notification for recruiting for the technical manager position. There are 17 positions to be fully filled for these positions.

Created on: Jun 21, 2021 06:13 IST

CSIR-NBRI 2021 recruitment: Apply for technical agent positions

CSIR – National Botanical Research Institute (NBRI) Recruitment 2021: CSIR – National Botanical Research Institute (NBRI) has solicited applications from those eligible for the recruitment of 17 technical officer positions. Interested and eligible individuals can apply for the positions online by visiting the official website of CSIR – National Botanical Research Institute (NBRI). Individuals should note that the application deadline is July 23, 2021.

National Botanical Research Institute (NBRI), Rana Pratap Marg, Lucknow – 226001 (Uttar Pradesh) is soliciting applications from eligible Indian citizens for recruitment for the following Group III (Technical) staff positions. The deadline for submitting applications is July 23, 2021.

Important date:

  • Deadline for submitting the application form: July 23, 2021

CSIR – National Botanical Research Institute (NBRI) Details of the technical manager

Name of positions

Number of messages

Senior Technical Officer

10 posts

Technical officer

07 posts


17 posts

Eligibility Technical manager job

Name of positions

Qualification and age limit

Senior Technical Officer

M.Sc. Post-diploma in botany / chemistry / microbiology with a minimum of 55% of marks (OR) B. Pharma with a minimum of 55% of marks and 02 years of professional experience in the field of pharmacognosy / chemotaxonomy / development of herbal medicines Age limit: 35 years.

Technical officer

Graduate Diploma (M.Sc.) in Environmental Sciences / Environmental Studies / Microbiology / Environmental Microbiology / Applied Microbiology with 55% of grades or B.Tech in Environmental Sciences and Environmental Engineering / industrial microbiology with 55% of scores. Age limit: 30 years.


  • Senior Technical Officer: Pay level 10 Rs. 56100-Rs. 177500.
  • Technical officer: Pay level 07 Rs. 44900-Rs. 142400.

Download our Sarkari Naukri app on Play Store

How to register

Interested and eligible individuals can apply for the positions online by visiting the official website of CSIR – National Botanical Research Institute (NBRI). Persons should note that the deadline for application is July 23, 2021. Application form in prescribed format downloaded from the official website of the NBRI. Completed applications as well as self-certified photocopies of documents are sent to CSIR-NBRI. For more details, visit the official NBRI website (nbri.res.in). The deadline for receipt of applications is July 23, 2021 until 6:00 p.m.

Also read the latest Job News Articles

SU announces schedule of entrance tests for admission to MS degree programs, M.Phil

The Director of Research and Graduate Studies at Sindh Jamshoro University on Friday announced the schedule of admission tests for admissions to various disciplines under the Masters and Masters of Philosophy programs for the 2021 academic year. .

HYDERABAD, (UrduPoint / Pakistan Point News – June 18, 2021): The Director of Research and Graduate Studies at Sindh Jamshoro University on Friday announced the admission test schedule for admissions in various disciplines under the Masters and Masters programs in Philosophy for the 2021 academic year.

According to the spokesperson for the university, the entrance test for applicants for admission in the disciplines of English linguistics, English literature, business administration, commerce, Islamic culture, Urdu, Sindh, Public Administration, Economics, Sociology, Muslim History, Criminology, International Relations, Politics Science, Psychology, Genetics, Microbiology and Biochemistry will take place June 28 at 10 am in the departments concerned.

The entrance test of candidates for admissions in the disciplines of zoology, I.

I., Software Engineering, Data Sciences, Telecommunications, Electronics, Computer Science, Mathematics, Physics, Inorganic Chemistry, Physical Chemistry and Analytical Chemistry will take place on June 29 at 10 a.m. in the relevant departments.

The entrance test of applicants for admission to the disciplines of chemical sciences, geography, botany, physiology, environmental sciences, physical education and health, studies of gender, statistics, pharmacy, pharmacognosy, pharmacology and pharmacy practice will take place on July 1 in the relevant departments, while the entrance test for admissions to the faculty of education will have held on July 2 at the Elsa Kazi campus in Hyderabad.

UM student selected for medicinal botany scholarship

OXFORD, Mississippi – Hayley Prescott, a graduate student in the Department of Biomolecular Sciences, University of Mississippi School of Pharmacy, has been named the recipient of the Anne S. Chatham Fellowship in Medicinal Botany by the Garden Club of America.

Hayley prescott

The scholarship, established in 1997, is administered by the Missouri Botanical Garden. Prescott received the award for his “Botanical Aphrodisiacs for Women’s Health” project. She received an annual grant of $ 4,500 which will allow her to continue her research on the subject.

“While I was at the University of Mississippi, I focused on botanical aphrodisiacs and their applications in women’s health, particularly in female sexual dysfunction,” said Prescott, who is pursuing a doctorate. in pharmaceutical sciences. “I’ve always been interested in the ‘why and how’ of herbal medicine – why these plants have been used all this time and how they work. “

Prescott credited her advisor, Ikhlas Khan, director of the National Center for Natural Products Research and distinguished professor of pharmacognosy, for encouraging her to find research projects that inspire her.

“Dr. Khan is an atypical advisor in that he gave me the freedom to pursue a project that I was interested in and passionate about, and I am very grateful for that,” Prescott said. “He always has was motivated by the desire that we, the students, be independent in order to benefit our future careers. ”

Khan praised Prescott’s ambition and creativity as a researcher and student.

“Hayley has always been a free thinker and not afraid to handle difficult tasks, and her research topic shows it,” Khan said. “It’s a pleasure to work with her, and I was happy to have her as a member of the group.

Prescott also cited Nicole Ashpole, assistant professor of pharmacology at UM, as an important mentor and an example to follow.

“Part of me means having a strong female mentor is extremely important in my development as a young scientist, but it’s so much more than that limiting label,” Prescott said. “Dr. Ashpole is by far one of the best and hardest working mentors, leaders and scientists that we have here at the University of Mississippi.

Prescott plans to put her education into action as she is interested in political work around dietary supplements or the practice through community work.

“I started out doe-eyed, wanting to change the world with my research and my degree,” Prescott said. “But the goal at the start and finish was really the same, and it’s my desire to help people.”

The Institute of Pharmaceutical Sciences will open at LU

Lucknow, June 9 The University of Lucknow (LU) is preparing to open an Institute of Pharmaceutical Sciences (IPS) spread over 8,170 square meters on its second campus in the Jankipuram region.

Students aspiring to a career in pharmacy will soon have a dedicated government institute in the state capital.

The proposal to open the institute under the direction of the Faculty of Engineering was given the green light at the university’s finance committee meeting and it will now be submitted to the executive committee on June 11 for final approval.

The three-story high-tech building will be equipped with four state-of-the-art laboratories and will gradually be developed into a dedicated research institute with the establishment of modern laboratories for microbiology, pharmaceutical chemistry, central instrumentation, biotechnology, l human anatomy, physiology and pharmacognosy.

Construction work on the institute is expected to be completed by next year. Until then, pharmacy courses will be held in the Faculty of Engineering.

According to official sources, two self-funded Bachelor in Pharmacy (B.Pharma) courses with 100 places and Diploma in Pharmacy (D.Pharma) with 60 places will be offered at the institute for which 33 contractual faculties will be appointed.

The B.Pharma course will be four years (eight semesters) while the D.Pharma will be two years (annual model). The M.Pharma course may start after two years in accordance with the policy of the Pharmacy Council of India, New Delhi.

Application for both courses in the 2020-2021 academic session will be invited shortly once the university receives approval from the Pharmacy Council of India.

IPS will include four departments: pharmacy, pharmaceutical chemistry, pharmacology and pharmacognosy.

IPS Director Naveen Khare said: “The institute’s main objective is to excel in pharmacy education, to engage in cutting-edge research to advance healthcare. and drug discovery, which is the need of the hour at the time of the Covid pandemic. Biomedical and clinical sciences and practices will be at the center of concerns. “

Disclaimer: This article was posted automatically from an agency feed without any text changes and has not been reviewed by an editor

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LU’s High-Tech Pharmaceutical Institute to be Completed by Next Year | Lucknow News

Lucknow: Students aspiring to a career in pharmacy will soon have a dedicated government institute in the city to make their dreams come true.
Lucknow University is preparing to open an Institute of Pharmaceutical Sciences (IPS) covering a vast area of ​​8,170 square meters on its second campus in Jankipuram.
The proposal to open the institute under the leadership of the Faculty of Engineering was given the green light at the university’s finance committee meeting and it will now be submitted to the executive committee on June 11 for final approval.
The three-story high-tech building will be equipped with four state-of-the-art laboratories and gradually developed into a dedicated research institute with the establishment of modern laboratories for microbiology, pharmaceutical chemistry, central instrumentation, biotechnology, human anatomy, physiology and pharmacognosy.
Construction work on the institute is expected to be completed by next year, by then pharmacy classes will be held on one floor of LU’s engineering faculty.
Two self-funded courses – license in pharmacy (BPharma) with 100 places and diploma in pharmacy (DPharma) with 60 places – will be offered at the institute for which 33 contractual faculties will be designated.
Application for two courses for the 2020-2021 academic session will be invited shortly once the university receives approval from the Pharmacy Council of India.
IPS will include four departments: pharmacy, pharmaceutical chemistry, pharmacology and pharmacognosy.
The BPharma course will be four years (eight semesters) while D Pharma will be two years (annual model). The M Pharma course can start after two years in accordance with the policy of the Pharmacy Council of India, New Delhi.
“The main objective of the institute is to excel in teaching pharmacy, to engage in cutting-edge research to advance healthcare and drug discovery, which is the need for l ‘Time for the Covid 19 pandemic. Innovative research in pharmaceutical, biomedical and clinical sciences and practices will be targeted, ”said IPS director Professor Naveen Khare.


Antibiotics can treat human diseases like cancer, not just bacterial infections

An antibiotic (green), linked to the human-type yeast ribosome (gray), allows the synthesis of some proteins (shown in orange, purple and blue) but not others (dark green). Credit: Maxim Svetlov / UIC

UIC researchers are proving that drugs designed for bacteria have the potential to act on human cells.

Antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, can also be used to treat human illnesses, like cancer, according to researchers at the University of Illinois at Chicago. Theoretically, at least.

As shown in a new Nature Communication study, the UIC College of Pharmacy team showed in laboratory experiments that eukaryotic ribosomes can be modified to respond to antibiotics in the same way as prokaryotic ribosomes.

Alexander Mankin

Alexander Mankin, Alexander Neyfakh Professor of Medicinal Chemistry and Pharmacognosy at UIC College of Pharmacy. Credit: UIC Photo Services / UIC

Fungi, plants, and animals, like humans, are eukaryotes; they are made up of cells with a clearly defined nucleus. Bacteria, on the other hand, are prokaryotes. They are made up of cells that do not have a nucleus and have different structure, size and properties. The ribosomes of eukaryotic and prokaryotic cells, which are responsible for synthesizing proteins necessary for cell growth and reproduction, are also different.

“Some antibiotics, used to treat bacterial infections, work in interesting ways. They bind to the ribosome of bacterial cells and very selectively inhibit protein synthesis. Some proteins are allowed to be made, but others are not, ”said Alexander Mankin, Alexander Neyfakh professor of medicinal chemistry and pharmacognosy at UIC College of Pharmacy and lead author of the study. “Without these proteins, bacteria die. “

When people use antibiotics to treat an infection, the patient’s cells are not affected because the drugs are not designed to bind to ribosomes of different shapes than eukaryotic cells.

“Because there are many human diseases caused by the expression of unwanted proteins – this is common in many types of cancer or neurodegenerative diseases, for example – we wanted to know if it would be possible to use an antibiotic. to prevent a human cell from making the unwanted proteins, and only the unwanted proteins, ”Mankin said.

To answer this question, Mankin and the study’s first author, Maxim Svetlov, an assistant research professor in the Department of Pharmaceutical Sciences, turned to yeast, a eukaryote with cells similar to human cells.

Maxim Svetlov

Maxim Svetlov, Research Assistant Professor in the Department of Pharmaceutical Sciences at UIC College of Pharmacy. Credit: Svetlov / UIC

The research team, which included partners from Germany and Switzerland, did a “cool thing,” Mankin said. “We designed the yeast ribosome to look more like bacteria.”

Mankin and Svetlov’s team used biochemistry and fine genetics to modify over 7,000 nucleotides in ribosomal yeast RNA, which was enough for a macrolide antibiotic – a common class of antibiotics that work by binding to bacterial ribosomes – to act on the yeast ribosome. Using this yeast model, the researchers applied genomic profiling and high-resolution structural analysis to understand how each protein in the cell is synthesized and how the macrolide interacts with the yeast ribosome.

“Thanks to this analysis, we understood that depending on the specific genetic signature of a protein – the presence of a” good “or” bad “sequence – the macrolide can stop its production on the eukaryotic ribosome. or not, ”Mankin said. “This has shown us, conceptually, that antibiotics can be used to selectively inhibit protein synthesis in human cells and used to treat human disorders caused by ‘bad’ proteins.”

The experiments of UIC researchers constitute a platform for future studies. “Now that we know the concepts work, we can look for antibiotics that can bind to unmodified eukaryotic ribosomes and optimize them to only inhibit proteins that are bad for a human,” Mankin said.

Reference: “Context-specific action of macrolide antibiotics on the eukaryotic ribosome” by Maxim S. Svetlov, Timm O. Koller, Sezen Meydan, Vaishnavi Shankar, Dorota Klepacki, Norbert Polacek, Nicholas R. Guydosh, Nora Vázquez-Laslop, Daniel N Wilson and Alexander S. Mankin, May 14, 2021, Natural communications.
DOI: 10.1038 / s41467-021-23068-1

Additional study co-authors are Dorota Klepacki and Nora Vázquez-Laslop from UIC; Timm Koller and Daniel Wilson from the University of Hamburg; Sezen Meydan and Nicholas Guydosh of the National Institutes of Health; and Norbert Polacek and Vaishnavi Shankar from University of Bern.

This work was supported by grants from the National Institutes of Health (R35 GM127134, DK075132, 1FI2GM137845), the German Research Foundation (WI3285 / 6-1) and the Swiss National Science Foundation (31003A_166527).

Medicinal plants of Nigeria: Tribulus terrestris (Puncture vine)

This week, I want to start by thanking those who sent me text messages asking that the plants of Picralima nitida (Abere) be planted in their homes. This shows that my discussion of having orchards at home is bearing fruit. Do you know that the drugs commonly prescribed for men with low sperm count are called Manix capsules? Most men know this. Tribulus terrestris is one of its ingredients and it is the plant that I will be talking about today. It is one of the plants that I saw at the Medicinal Plant Gardens of the Department of Pharmacognosy, Obafemi Awolowo University, Ile-Ife, Osun State, when I went there last year. I don’t have the local names but among its many English names, I chose the vine puncture. If you Google Tribulus terrestris, you will see images of the plant.

Let me share a story with you before I continue. A person close to me had a pelvic scan during a medical exam in 2016 because they could not conceive for a long time. The result of the scan showed a cyst on her right ovary. I started a treatment on it with spices such as ginger, turmeric and other things found in nature. As they say, a prophet has no honor in his own country. Our closeness must have made her doubt the treatment and she had unprotected sex when she shouldn’t have. The next thing we saw was pregnancy! Yes, ovarian cysts are treatable without surgery!

Now back to Tribulus terrestris. It is a plant of the Zygophyllaceae family. In Ayurveda, the root and the fruits are used for male virility and general vitality. People with health problems and diseases such as hormonal imbalance, sexual problems, heart problems, and various kidney and skin diseases use the plant. There is something important that I would like to address here, despite the marketing claims, the plant does not appear to increase testosterone in humans. This conclusion is based on studies in men and women of different health states and ages. A review analyzed the results of 12 major studies on the effects of the plant in men and women aged 14 to 60 years. The studies lasted from 2 to 90 days, and participants included healthy people and people with sexual problems. Researchers found that this supplement did not increase testosterone. Other researchers have found that Tribulus terrestris may increase testosterone in some animal studies, but this result is generally not seen in humans. Some researchers have found that when men with reduced sex drive consumed 750 to 1,500 mg of Tribulus terrestris per day for two months, their sexual desire increased by 79%. In addition, 67% of women with low libido experienced an increase in sexual desire after taking supplements of 500 to 1500 mg for 90 days. So this means that Tribulus improves libido and sexual well-being without increasing testosterone. Athletes who use it to build muscle because they believe it increases testosterone levels may need to look more for other testosterone boosting supplements.

Tribulus is used for kidney stones, painful urination, a kidney disorder called Bright’s disease, and as a “water pill” (diuretic) to increase urination. It is used for skin disorders like eczema (atopic dermatitis), psoriasis and scabies. It is used for male sexual problems, such as erectile dysfunction, the involuntary release of semen without an orgasm (spermatorrhea), and to increase sexual desire. It is used for heart and circulatory problems such as chest pain, high blood pressure, high cholesterol, and “tired blood” (anemia). It is used for digestive problems such as colic, intestinal gas (gas), constipation and to expel parasitic intestinal worms. It is used for pain and swelling (inflammation) of the tissues that line the mouth (stomatitis), sore throats and cancer, especially tumors of the nose.

Women use tribulus to tone muscles before childbirth, to induce abortion, and to stimulate milk production. Some people use tribulus for gonorrhea, liver disease (hepatitis), inflammation, joint pain (rheumatism), leprosy, cough, headache, dizziness (vertigo), chronic fatigue syndrome and improving athletic performance. It is also used to stimulate appetite and as an astringent, tonic and mood booster. The root and fruit of the plant have been used in traditional Chinese medicine and Indian Ayurvedic medicine.

Although people often take Tribulus terrestris for its potential effects on sexual function and testosterone, it has also been studied for other important effects. Animal studies have shown that Tribulus terrestris can lower blood sugar levels, help protect against damage to blood vessels, and help prevent increases in blood cholesterol. One study looked at the effects of taking 1000 mg of Tribulus terrestris per day in 98 women with type 2 diabetes. Some studies have shown that these extracts also have cytotoxic and antimicrobial activities.

In Bulgaria, the plant is used as a popular medicine to treat impotence. In addition to all these applications, the Ayurvedic Pharmacopoeia of India attributes its cardiotonic properties to the root and the fruit. In traditional Chinese medicine, the fruits were used for the treatment of eye disorders, edema, abdominal distension, emission, morbid leucorrhea, and sexual dysfunction. It is described as a drug of great value in the Shern-Nong Pharmacopoeia (the oldest known pharmacological work in China) in the restoration of depressed liver, for the treatment of breast fullness, mastitis, flatulence, acute conjunctivitis, headaches and vitiligo. In Unani medicine (traditional Arab medicine) it is used as a diuretic, mild laxative and general tonic. Tribulus is also marketed as a dietary supplement to improve sexual function and for bodybuilding due to the belief that it acts like testosterone in the body.

The leaves and shoots are eaten in East Asia. The stems were used as a thickener, added to diluted buttermilk to give it the appearance of undiluted buttermilk. The dried fruit of the herb is effective in most disorders of the genitourinary tract. It is an essential constituent of Gokshuradi Guggul, a powerful Ayurvedic medicine used to support the proper functioning of the genitourinary tract and to eliminate urinary stones.

In a phytopharmacological overview of Tribulus terrestris Chhatre et al, the different parts of Tribulus are said to contain a variety of chemical constituents which are medically important, such as flavonoids, flavonol glycosides, steroidal saponins and alkaloids. The plant has diuretic, aphrodisiac, antiurolithic, immunomodulatory, antidiabetic, absorption enhancing, hypolipidemic, cardiotonic, central nervous system, hepatoprotective, anti-inflammatory, analgesic, antispasmodic, anticancer, antibacterial, anthelmintic, larvicide and anticariogenic activities.

Cyclophosphamide is the most commonly used cancer and immunosuppressive drug that causes several toxic effects, especially on the reproductive system. In a study entitled “Tribulus terrestris Protects against Male Reproductive Damage Induced by Cyclophosphamide in Mice”, by Pavin et al, the study demonstrated the role of the dry extract of Tribulus in the improvement of the alterations induced by the administration of CP in the testes of mice.

You can buy Tribulus terrestris at major drugstores. I kept the shocking part until the end, Tribulus terrestris is a weed! Copyright PUNCH.

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Can antibiotics treat human diseases in addition to

image: An antibiotic (green), bound in the human-type yeast ribosome (gray), allows the synthesis of some proteins (shown in orange, purple and blue) but not others (dark green).
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Credit: Maxim Svetlov / UIC

Antibiotics used to treat common bacterial infections, like pneumonia and sinusitis, can also be used to treat human illnesses, like cancer, according to researchers at the University of Illinois at Chicago. Theoretically, at least.

As shown in a new Nature Communication study, the UIC College of Pharmacy team showed in laboratory experiments that eukaryotic ribosomes can be modified to respond to antibiotics in the same way as prokaryotic ribosomes.

Fungi, plants and animals – like humans – are eukaryotes; they are made up of cells with a clearly defined nucleus. Bacteria, on the other hand, are prokaryotes. They are made up of cells that do not have a nucleus and have different structure, size and properties. The ribosomes of eukaryotic and prokaryotic cells, which are responsible for synthesizing proteins necessary for cell growth and reproduction, are also different.

“Some antibiotics, used to treat bacterial infections, work in interesting ways. They bind to the ribosome of bacterial cells and very selectively inhibit protein synthesis. Some proteins can be made, but others are not,” he said. said Alexander Mankin, the Alexander Neyfakh Professor of Medicinal Chemistry and Pharmacognosy at UIC College of Pharmacy and lead author of the study. “Without these proteins being made, bacteria die.”

When people use antibiotics to treat an infection, the patient’s cells are not affected because the drugs are not designed to bind to ribosomes of different shapes than eukaryotic cells.

“Because there are many human diseases caused by the expression of unwanted proteins – this is common in many types of cancer or neurodegenerative diseases, for example – we wanted to know if it would be possible to use an antibiotic. to stop a human cell from making unwanted proteins, and only unwanted proteins, ”Mankin said.

To answer this question, Mankin and the study’s first author, Maxim Svetlov, an assistant research professor in the Department of Pharmaceutical Sciences, turned to yeast, a eukaryote with cells similar to human cells.

The research team, which included partners from Germany and Switzerland, did a “cool thing,” Mankin said. “We designed the yeast ribosome to look more like bacteria.”

Mankin and Svetlov’s team used biochemistry and fine genetics to alter over 7,000 nucleotides in yeast ribosomal RNA, which was enough to make a macrolide antibiotic – a common class of antibiotics that work by binding to bacterial ribosomes – acts on the yeast ribosome. Using this yeast model, the researchers applied genomic profiling and high-resolution structural analysis to understand how each protein in the cell is synthesized and how the macrolide interacts with the yeast ribosome.

“Thanks to this analysis, we understood that depending on the specific genetic signature of a protein – the presence of a” good “or” bad “sequence – the macrolide can stop its production on the ribosome. eukaryotic or not, ”Mankin said. “This has shown us, conceptually, that antibiotics can be used to selectively inhibit protein synthesis in human cells and used to treat human disorders caused by ‘bad’ proteins.”

The experiments of UIC researchers constitute a platform for future studies. “Now that we know the concepts work, we can search for antibiotics that can bind to unmodified eukaryotic ribosomes and optimize them to only inhibit proteins that are bad for humans,” Mankin said.


Additional study co-authors are Dorota Klepacki and Nora Vázquez-Laslop from UIC; Timm Koller and Daniel Wilson from the University of Hamburg; Sezen Meydan and Nicholas Guydosh of the National Institutes of Health; and Norbert Polacek and Vaishnavi Shankar from the University of Bern.

This work was supported by grants from the National Institutes of Health (R35 GM127134, DK075132, 1FI2GM137845), the German Research Foundation (WI3285 / 6-1) and the Swiss National Science Foundation (31003A_166527).

Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of any press releases posted on EurekAlert! by contributing institutions or for the use of any information via the EurekAlert system.

Medicinal plants of Nigeria: Securidaca longipedunculata (Ipeta)

Recently someone sent me a photo of an anti-cancer tea bag made by the Department of Pharmacognosy at the University of Lagos. I was able to speak with Dr Mutiat Ibrahim from the department. She sent me pictures of the other products they have. I was so excited when I saw honey among the photos. I haven’t had honey for a long time because the beekeeper who supplies me couldn’t do it. Seeing this one that has been lab tested for authentication pleases me. I believe in products like this because a lot of research has been done on them. They are not the type to produce charlatans.

Today I am going to talk about securidaca longipedunculata commonly known as Violet tree. The plant has a reputation for a wide range of medicinal, pharmacological and therapeutic properties. It is reported that almost all parts of the plant are used by humans for different ailments. It belongs to the Polygalaceae family. It is a medicinal plant indigenous to Africa and has an important place in traditional medicine as well as in modern medicine. It is used to treat sexually transmitted infections, hernias, cough, fever, ascariasis, constipation, headache, rheumatism, upset stomach, tuberculosis, pain, epilepsy, pneumonia, skin infections. She is known locally as Uwar magunguna in Hausa, literally meaning “the mother of all drugs”, in homage to her many medicinal uses. In Igbo, it is “ezeogwu” which means “king of drugs”, which suggests its great therapeutic power in diseases, especially in inflammatory disorders where it is popular. It’s Ipeta in Yoruba. The root of this plant is traditionally used to treat yeast infection, fever, headache, cancer, rheumatism, tuberculosis, diabetes, venereal disease, syphilis, sexual impotence, toothache, pain, epilepsy, seizures, constipation, pneumonia, back pain, blood purification, sexually transmitted infections, skin infections and also used as an aphrodisiac. A root decoction is used to speed up labor.

The leaves are locally used to treat wounds, epilepsy, headaches, stomach aches, infertility, snakebites, toothaches, cancer, skin infections, dislocated jaw, the treatment of wounds, sores, coughs, venereal diseases, snakebite, tuberculosis, bilharzia and seizures in children. It is used for contraceptives, as a purgative and to expel placentas.

The stem bark is traditionally used to treat epilepsy, upset stomach, venereal disease, skin disease, dysentery, malaria, typhoid, inflammation, lung ailments, constipation, viral infections, snakebites and infertility. The whole plant is used for washing the mouth and treating infections such as oral thrush. It treats excessive coughing and other opportunistic infections associated with the human immunodeficiency virus. The roots or pounded seeds can be used as soap and bleach. A fiber obtained from the inner bark can be used like cotton to weave coarse cloth, fishing nets and baskets. The plant is also used for the construction of huts, brooms, poles, etc.

Extracts from the bark of leaves and roots have antibacterial and antifungal activities. In addition, the stem bark extract of this important plant is active against clinical bacterial isolates of Escherichia coli, Salmonella typhi, Staphylococcus aureus, Shigella dysenteriae, Pseudomonas aeruginosa and Klebsiella pneumonia. In fact, one study supported the use of the stem bark in the management of bacterial disease and, as such, could serve as a potential source of antibacterial drugs. The bark of the stem contains more antibacterial agents than the other parts. The root bark and leaf extracts are also believed to have antioxidants. Methanol root bark extracts have shown good anti-inflammatory activity. The roots and bark are taken orally, either as a powder or as an infusion to treat illnesses. Usually, a poultice of the root bark of this plant is applied topically to the inflamed joints in the herbal treatment of inflammation and rheumatic disorders. Powdered roots or wood scrapings are used to treat headaches by rubbing them on the forehead, while root infusions are used to wash tropical ulcers. The root is also chewed as a stimulant.

It is the most popular of all the traditional herbal medicines in South Africa and is used for almost every disease imaginable. The root is used as a taenifuge (an agent that expels tapeworms) and an anthelmintic (anthelmintics are a group of antiparasitic drugs that expel parasitic worms) in French Guinea and Senegal. The plant has been used in the treatment of rheumatic ailments, seizures, fevers, headaches and various other inflammatory conditions in West Africa. In northern Nigeria, it is traditionally used in the treatment of cancer by most traditional medicine practitioners in the region. The aqueous extract of the root is used as psychopharmacological agents. In the Nsukka community of Enugu State, a poultice of the root bark of S. longipedunculata is commonly used for the treatment of rheumatic conditions and inflammation. In Limpopo (South Africa), the VhaVenda use the roots for mental disorders and as protection against illnesses of children during breastfeeding. They (vhaVenda people) also mix the powdered root with mageu (corn or sorghum drink) and it is given to a man to drink if he is sexually weak. In Iringa (a town in Tanzania) it is used for the management of certain manifestations of non-insulin-dependent diabetes. A decoction of the dried bark is used to treat bacterial infections and inflammation, insanity and epilepsy. The leaves are used to treat wounds, sores, coughs, venereal diseases, snakebites and as a purgative. It is used to treat tuberculosis. Oral administration of a root decoction has been shown to produce a sedative effect. Cooked leaves are said to be an effective treatment for snakebites.

This tree is also commonly used as a pesticide against beetles in stored grains. This technique can be useful for small, subsistence farmers in Africa who are unable to purchase synthetic pesticides.

Biological activities of the plant include anti-inflammatory, antioxidant, antiparasitic, histopathological, antimicrobial, antidiabetic, antiplasmodial, antitrypanosomal, anticonvulsant, enzyme inhibitor, insecticide, molluscicides and pesticides activities. The plant is rich in essential oils. Different classes of bioactive compounds which include phenolic acids, xanthones, glycosides, saponins, steroids, fatty acids, volatile oils, flavonoids, alkaloids and sucrose derivatives have been isolated from different parts of Securidaca longipedunculata .

A study entitled “Ethanol Extract of Securidaca longipedunculata Induces Apoptosis in Brain Tumor (U87) Cells”, by Ngulde et al, aimed to evaluate the anticancer activity of the plant extract. The result of this work supported folklore use because the ethanol extract inhibited the proliferation of the U87 cell line. In another study titled “Anti-inflammatory activity of root bark extracts of securidaca longipedunculata fres (polygalaceae),” by Okoli et al, pharmacological screening of root bark extracts of S. longipedunculata revealed that the The root bark has a potent anti-inflammatory effect in topical and systemic models of acute inflammation.

Securidaca longipedunculata is popular for its anticancer activity. It is common in savannah areas; people around Oke-Ogun, Ogbomoso, Ilorin and the North generally know him. Have you also noticed that it is also an aphrodisiac? Nature seems to love people!

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GlyCORE to Host Inaugural Mid-South Glycoscience Meeting

The inaugural Mid-South Glycoscience meeting, hosted by the UM Glycoscience Center of Research Excellence, is scheduled for July 19 at the Thad Cochran Research Center. The one-day event will allow glycoscience researchers and their trainees to present their work, network and establish new opportunities for collaboration. Photo by Robert Jordan / Ole Miss Digital Imaging Services

OXFORD, Mississippi – The Glycoscience Center of Research Excellence at the University of Mississippi School of Pharmacy is expected to host the first Mid-South Glycoscience Meeting.

The meeting is scheduled for July 19 at the Thad Cochran Research Center. The one-day event will be a place for Mid-South glycoscience researchers and their trainees to showcase their work, network and establish new opportunities for collaboration.

GlyCORE researchers are studying how carbohydrates and molecules containing carbohydrates affect human health. The event is a milestone for the center, which was founded in 2020, said Joshua Sharp, director of GlyCORE and associate professor of pharmacology, chemistry and biochemistry.

Joshua Sharp

“This is our introduction to the glycoscience community in the region,” said Sharp. “We have many unique resources here that we would like to introduce other Mid-South researchers to, and a lot of exciting work from our faculty members that we would like to spread the word to the community.”

Samir Ross, GlyCORE Co-Director and Professor of Pharmacognosy, echoed Sharp’s sentiments, saying this was an opportunity to introduce GlyCORE to the community.

“This meeting will be able to show the cutting-edge research facilities needed to support modern research in glycoscience, including the analytical and biophysical research core, the imaging research core, and the computer and bioinformatics research core.” Ross said.

Sharp also hopes the meeting will bring the Mid-South glycoscience community together in a new and lasting way.

“This particular region did not have a glycoscience center and therefore did not have unifying events or meetings,” Sharp said. “We hope this meeting will help regional glycoscientists form a collaborative community, promote the sharing of ideas and resources, and become a little more impactful and competitive on the international glycoscience scene.”

Samir A. Ross

Ross added that the meeting will be beneficial for all participants, regardless of their level of experience.

“This meeting will be a great opportunity for senior glycoscientists and biomedical researchers who have just entered the field to meet and strengthen ties,” he said.

Meeting attendees will also hear from an impressive roster of guest speakers. These include Nancy Dahms of the Medical College of Wisconsin, Linda C. Hsieh-Wilson of the California Institute of Technology, Steven D. Townsend of Vanderbilt University, Charlie Fehl of Wayne State University and Maciej Walczak of the University. from Colorado.

“Our panel of guest speakers covers a vast space and represents a wide range of available glycosciences,” said Sharp.

A virtual option will be available for attendees who cannot attend the meeting in person, and it will include opportunities to interact with presenters, Sharp said. In the event of restrictions related to COVID-19, the meeting will move to a fully virtual format.

Visit the GlyCORE website for more information and to register for the meeting.

Obituary of David Carew (1928 – 2021) – Iowa City, IA

Dr David Pease Carew

Iowa City – Dr. David Pease Carew, Emeritus Professor of Medicinal and Natural Products Chemistry at the College of Pharmacy at the University of Iowa, died on April 26, 2021 in hospitals and clinics at the University of Iowa in Iowa City.

Dave was born October 21, 1928 in Monson, MA, son of Ralph and Sara Carew. His father died of polio when Dave was only 3, leaving his family, which included six sisters and a brother, to survive the Depression with their mother. Dave attended High School in Monson, Massachusetts, where he was an outstanding student, athlete, and class president. After high school, he served two years in the United States Army during the occupation of Japan.

On September 3, 1951, Dave married his high school girlfriend, Shirley Makepeace. Dave and Shirley first lived in Boston while Dave pursued his undergraduate and master’s degree in pharmacy at Massachusetts College of Pharmacy, then in Connecticut where he received his doctorate from the University of Connecticut. In 1957, Dave, Shirley, and their three young children moved to Iowa City where he joined the faculty at the University of Iowa’s College of Pharmacy as an assistant professor of pharmacognosy.

In Iowa, Dr. Carew has conducted research on tissue culture of medicinal plants. Part of his research involved learning how chemically active compounds in medicine are formed in plants and producing medicinal compounds using plant cell cultures. In addition to his research and teaching in Iowa, Dr. Carew served as Assistant Dean for Undergraduate Affairs at the College of Pharmacy, Acting Dean and Director of Alumni Relations. In addition to a multitude of professional articles, he has published or co-published over 35 research studies. During his tenure at the University of Iowa, Dr. Carew served on many college, university, and national committees, including the Honorary President of the Iowa Pharmacists Association and the President of the American Society of Pharmacognosy.

Dr Carew has lectured around the world on plant tissue culture and has been appointed a member of the American Association for the Advancement of Science, the American Pharmacists Association-Academy of Pharmaceutical Research and Science, and the Academy of Pharmaceutical Scientists. Teaching and leading his undergraduate and graduate students were his real passions. As a result of his work, Dr. Carew received the University of Iowa’s Marion L. Eight Award for “dedication, interest and interaction with students” as well as the Michael J. Brody Award for “outstanding contributions to. UI and the community. ”

In retirement, Dave and Shirley continued their many travels around the world. He has always enjoyed her gourmet cuisine, being her assistant gardener and wearing one of the many sweaters she knitted for him during their 62 years of marriage. Dave’s integrity, kindness and dry wit were the hallmarks of his personality. His eyes twinkled when he knew he had said something intelligently funny.

He was always interested and concerned about other people and the way “you” were doing.

Dave was predeceased by his wife, parents and sisters: Mary Emerson, Jessie Gates, Helen Morris, Sara Jean Ouellette and Rachel Watrous. He is survived by his daughter Susan (Jud) Te Paske of Cordova, TN; sons Bruce (Peggy) Carew of North Venice, Florida and Steven (Diane) Carew of Grimes, IA; grandchildren Neal Te Paske, Loveland, CO; David Carew, Appleton, WI;

Sarah Carew (Ben Luther), Onalaska, WI; Russell (Heather) Carew, Ankeny, IA; Brian Carew, Ankeny, IA; and great-grandchildren Melody, Kamryn and Bailey Carew; Brother Ralph (Millie) Carew, Lansdale, Pennsylvania; and Sister Florence Fenton, Monson, MA.

The family expresses their deep gratitude to the hardworking, caring and imaginative staff at Oaknoll Retirement Residence for the care of their father, grandfather, great-grandfather and brother.

Due to concerns related to Covid, no public service will be organized. Memorial contributions can be made to CommUnity Crisis Services and Food Bank Food Bank, 1121 Gilbert Court, Iowa City, Iowa 52240, https://builtbycommunity.org/foodbank/. Online condolences can be sent to his family at www.gayandciha.com.

Published by Iowa City Press-Citizen from April 29 to May 1, 2021.

URI’s online medical cannabis program to complete inaugural class – URI News


KINGSTON, RI – April 28, 2021 – The inaugural class of the University of Rhode Island College of Pharmacy’s groundbreaking online undergraduate certificate program in Cannabis Therapeutic Studies is expected to graduate this spring, adding qualified staff to one of the fastest growing industries in the country.

The 21 students who are expected to complete their studies on April 26 will participate in a virtual launch ceremony on May 19, just before the URI launch weekend. Dean of Pharmacy Paul Larrat and Professor Navindra Seeram will address the graduates. URI President David Dooley and Provost Donald H. DeHayes will also offer their greetings.

The Medical Cannabis Studies Online Course aims to provide graduates with an in-depth knowledge of the safe production and dissemination of cannabis-related information and products to qualified patients. The certificate program offered by the College’s Department of Biomedical and Pharmaceutical Sciences caters for many diverse positions in industry including sales, brand ambassador, lab technicians, compliance / quality assurance , clinic management, and product development and manufacturing.

“This certificate is something that will help me grow in a short period of time,” said student Brendan Craveiro, who is expected to graduate in May. “I am currently working in the industry, I can see the growth happening every day. Many of the people I work with have a background in culture, but with this certificate I now bring post-culture experience to the workplace and contribute to the scientific part of the business including mining, sample preparation, laboratory work, etc. It has completed my cannabis knowledge base and I think it will really help me grow professionally in the industry.

The certificate program, taught by leaders in research on natural products, including phytocannabinoids such as CBD, consists of four 3-credit courses of seven weeks each, including the foundations of studies on the cannabis, cannabis product development, cannabis chemistry and pharmacognosy, and cannabis therapeutics.

The online nature of the program opens the course to students from across the country and allows those already working in busy medical facilities to complete the course at times that are convenient for them. This flexibility appealed to student Robin Maroney, a registered nurse working in cardiac rehabilitation. Several patients she worked with were interested in therapeutic cannabis, and Maroney wanted to be qualified to counsel them in therapy.

“I wanted to work as a cannabis consultant for patients, doctors and the general population. It is important to help the consumer understand the benefits of using cannabinoids as well as being able to manage pain, stress, anxiety, depression, etc. Said Maroney. “I firmly believe that people take control of their own health and learn to heal themselves using plants. This program gives legitimacy to my quest as it goes through the College of Pharmacy, which is so well respected.

The online medical cannabis program caters for several positions in the medical and cannabis fields. Students in the first year of the program represent several professions including pharmacists, nurses, lawyers, dieticians, cannabis growers, and budtenders, among others.

“The skills developed through the certificate program will prepare students for the evolution and expansion of the medical cannabis industry,” said Professor Navindra Seeram, President of Biomedical and Pharmaceutical Sciences. “Students who complete the certificate will be very competitive in several areas. “

Students who successfully complete the course will be awarded a 12-credit certificate. Visit the Undergraduate Certificate in Cannabis Studies website for more information and to apply for the next session. Applications for courses starting in fall 2021 are now open, with a deadline to apply of August 3.

Foraging in the forests of Door County – Door County Pulse


Our peninsula was lucky. The Paleo-Indians, who first lived here around 2,000 years ago, were primarily hunters and fishermen who did little to disturb the primeval forest.

This changed from the mid-1800s with settlement and agriculture, but the forest has since reclaimed Door County. According to Jake Schroeder, a forester with the Wisconsin Division of Forestry, 48% of Door County is now classified as forest, which ranks it 24th out of 72 counties in the state.

David LaLuzerne, a self-proclaimed herbalist and forager, spends a lot of time in the woods of Door County.

“If you remove trees, a very important part of the whole ecosystem is removed,” he said. “After that it would be a chain reaction until it was all gone.”

During the 1970s, LaLuzerne was in the last class at UW-Madison School of Pharmacy to take a course in pharmacognosy, or the study of drugs derived from natural sources such as plants. He became more interested in incorporating herbal remedies – the source of natural healing – into his life and career.

The focus on medicinal plants led LaLuzerne to open three Green Earth vitamin and herbal stores in the Madison area that he operated for 20 years. And based on his travels in the United States, China, Peru, and across Europe, he has produced 120 episodes of HerbTV (herbtvonline.com) that have been viewed 1.2 million times on YouTube. He recently donated the entire collection to the American Botanical Council.

Since 2014, LaLuzerne has been “retired” in Ellison Bay, but at least half of his time is devoted to his work as an herbalist. During the winter he teaches at The Clearing, and interest in these courses has led him to the walks he leads to introduce people to the herbs and fungi growing in their environment that can be used to maintain health and well-being.

While various herbs are beneficial for certain parts of the body, LaLuzerne is concerned about advertising that touts herbal and fungal compounds as cure-alls for almost all human ailments. Most of these ads, he said, are based on limited research and / or unrelated.

On the other hand, he is intensely committed to raising awareness of the value of herbs and mushrooms not as a medicine, but as a food that helps to strengthen the ability of the body’s immune system to protect the body against them. bacteria, viruses, parasites and fungi that cause infections. and disease.

Forests provide habitat for about 90% of all terrestrial species, both plants and animals. Scientists say that forests are “reserves” for the genes of biodiversity, and that these reserves require immediate and continuous remediation.

“It’s like what happens with farmland,” LaLuzerne said. “If we don’t start regenerating it, it is estimated that we only have enough usable farmland in the world for an additional 60 crops.

Many of us will have great-grandchildren alive in 2082. If we do nothing, what will they eat?

New diarylamides as active oral diuretics

image: In the present study, a novel urea transporter (UT) inhibitor with a diarylamide scaffold was discovered by high throughput screening. Optimization of the hit compound E04 led to the identification of 1H, with oral diuretic activity, more potent inhibitory activity on UT-A1, favorable pharmacokinetic characteristics and without electrolyte disturbance.
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Credit: Acta Pharmaceutica Sinica B

Discovery of new diarylamides as active oral diuretics targeting urea transporters

Urea transporters (UT) play a vital role in the urinary concentration mechanism and are recognized as new targets for the development of salt-saving diuretics. Thus, UT inhibitors show promise for development as novel diuretics. In this study, the authors discovered a novel UT inhibitor with a high throughput screening diarylamide scaffold. Optimization of the inhibitor led to the identification of a promising preclinical candidate, N-[4-(acetylamino)phenyl]-5-nitrofuran-2-carboxamide (1H), with excellent UT inhibitory activity in vitro at the submicromolar level. The semi-maximal inhibitory concentrations of 1H against UT-B in mice, rats, and human erythrocytes were 1.60, 0.64, and 0.13 μmol / L, respectively.

Further investigation suggested that 8 mol / L 1H more potently inhibited UT-A1 at a rate of 86.8% than UT-B at a rate of 73.9% in MDCK cell models. More interestingly, the authors first discovered that oral administration of 1H at a dose of 100 mg / kg showed a superior diuretic effect in vivo without causing electrolyte imbalance in the rat. In addition, 1H did not exhibit apparent toxicity in vivo and in vitro, and possessed favorable pharmacokinetic characteristics. 1H shows promise as a novel diuretic to treat hyponatremia accompanied by volume expansion and may cause few side effects.


Article reference: Shun Zhang, Yan Zhao, Shuyuan Wang, Min Li, Yue Xu, Jianhua Ran, Xiaoqiang Geng, Jinzhao He, Jia Meng, Guangying Shao, Hong Zhou, Zemei Ge, Guangping Cheng, Runtao Li, Baoxue Yang , Discovery of new diarylamides as active oral diuretics targeting urea transporters, Acta Pharmaceutica Sinica B, 2021, ISSN 2211-3835, https://doi.org/10.1016/j.apsb.2020.06.001

Keywords: Urea transporter inhibitor, Diuretic, Structure optimization, Oral administration

The Journal of the Institute of Materia Medica, Chinese Academy of Medical Sciences, and Chinese Pharmaceutical Association.

Acta Pharmaceutica Sinica B (APSB) is a monthly journal, in English, which publishes important original research articles, rapid communications and high-quality journals on recent advances in all fields of pharmaceutical sciences – including pharmacology, pharmacy, medicinal chemistry , natural products, pharmacognosy, pharmaceutical analysis and pharmacokinetics. For more information, please visit https://www.journals.elsevier.com/acta-pharmaceutica-sinica-b/

Editorial committee: https://www.journals.elsevier.com/acta-pharmaceutica-sinica-b/editorial-board

The APSB is available on ScienceDirect.

Submissions to APSB can be made using Editorial Manager®.

CiteScore: 10.5

Impact factor: 7.097

5-year impact factor: 7.865

Source Impact normalized by paper (SNIP): 2,210

SCImago Journal (SJR) Rank: 1.792

ISSN 2211-3835

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A major side effect of consuming chia seeds – eat this not that


Chia seeds are often referred to as a superfood because they provide a ton of nutrients for minimal calories. While they should be enjoyed often, there is one major side effect you should be aware of before pouring several tablespoons of the substance into your morning oatmeal bowl.

Consumed in excess, chia seeds can cause a variety of digestive problems, including bloating.

There are several reasons why this can happen. For starters, chia seeds are very high in fiber, containing around 10 grams per 2 tbsp serving. According to the Food and Drug Administration (FDA), the recommended daily intake of fiber is 28 grams for a 2000 calorie diet.

As tempting as it may be to cut 36% of your daily fiber requirement with chia seeds alone, a 1 ounce serving at one time might not be the best decision for everyone. This is especially the case if you are currently on a low-fiber diet, which is the case with the average American, who only gets 16 grams of fiber per day.

To put it in perspective, by eating one serving of chia seeds, you would consume over 60% of your average fiber intake in one sitting. While fiber is incredibly beneficial to your health, and you should strive to achieve your recommended intake, consuming so much fiber with a meal when your body is not used to processing so much fiber can cause pain. digestive problems in some people.

You may experience bloating due to the high levels of a specific type of fiber in chia seeds, insoluble fiber, which makes up 50% of the seed’s nutritional makeup, according to an analysis published in the Recent Science Research Journal.

This type of fiber helps to retain water several times its weight, which helps to give bulk to the stool. In addition, a Journal of Pharmacognosy and Phytochemistry the review notes that the insoluble fiber in chia seeds accelerates gastrointestinal transit time because it helps promote bowel movements. However, water must be consumed in sufficient quantity for this to happen. Otherwise, you might experience bloating as the body works to move fiber through your digestive tract. (Related: The 7 Healthiest Foods To Eat Right Now).

Although some people may experience bloating when consuming chia seeds, once your body adjusts to consuming more and adequate fiber, you will be able to experience all of the incredible benefits of chia seeds. The fiber in chia seeds has been shown to help keep you full for longer, may help get rid of belly fat, may regulate blood sugar levels, and may help reduce the absorption of LDL (harmful cholesterol). in your bloodstream.

One way to reap the benefits of chia seeds without having to deal with gastrointestinal upset is to soak chia seeds in water before eating them. This way they will expand in the bowl, not in your abdomen. The Choosing Chia blog recommends using six parts liquid for one part chia (1/4 cup chia, 1.5 cups water) for a liquid consistency and four parts liquid for one part chia. (1/4 cup chia, 1 cup liquid) for a thicker consistency. The result? Chia pudding!

Bottom Line: Try not to take more than 2 tablespoons of chia seeds per day, especially if your gut is ultra-sensitive or you have gastrointestinal issues. Now be sure to check what happens to your body when you eat the seeds.

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Importance of pharmacognosy


Pharmacognosy is the study of drugs derived from natural sources. It forms an important part of pharmaceutical research and development.

Image Credit: James Pendleton / Shutterstock.com


Pharmacognosy involves the identification, physicochemical characterization, cultivation, extraction, preparation, quality control and biological evaluation of drugs. A plant, flower, root, animal, or plant leaf extract can be used to isolate the bioactive chemical.

Any herbal preparation that is used for health purposes, rather than just for nutritional supplementation or to add flavor to foods, is called a medicinal preparation. Some examples of such compounds include caffeine, salicylic acid, and certain chemotherapeutic, inotropic and anti-gout agents.

The term “pharmacognosy” was coined by Anotheus Seydler, a German botanist, from the two Greek words “pharmakon”, which means drug or medicine, and “gnosis”, which means knowledge. Even today, about a quarter of all prescription drugs in the United States contain one or more bioactive compounds derived from plants.

Pharmacognosy in drug development

According to the American Society of Pharmacognosy, the definition of pharmacognosy is “the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin, as well as research new drugs. from natural sources. “

Pharmacognosy is used by pharmaceutical companies to screen, characterize, and produce new drugs for the treatment of human diseases. Often, natural medicines cannot be mass produced, so they must be studied in order to develop synthetic biosimilars.

Synthetic production of these compounds allows for modifications, such as increases in their bioavailability, altered pharmacokinetics, and improved efficacy. These changes can turn an inactive raw plant extract into a potent drug, as has been observed in some anti-cancer drugs. Thus, natural compounds can provide excellent models for producing new drugs.

Pharmacognosy involves botanical knowledge to classify and name the plant and understand its genetic pattern and culture. Chemical knowledge is also important in this area to isolate, identify and quantitatively assess bioactive compounds in plant sources. Finally, pharmacology plays a role in pharmacognosy, as it allows researchers to detect and evaluate the biological properties of plants and to determine their effects on living systems.

A working knowledge of quality control is also required within pharmacognosy, as it ensures the correct identification and purity of the drug, as well as accurate testing of its efficacy and safety.

Importance of pharmacognosy

Traditionally, pharmacognosy has been recognized as an essential part of drug development and pharmacy education processes; however, the advent of new wonder drugs that can be synthesized in the laboratory has led to a decline in its practice.

Recently, many scientists now recognize that indigenous knowledge about the medicinal benefits of many plants should never be lost, as it provides excellent insight into the development of new drugs. For example, artemisinin from Artemisia annua Where ginghaosu tree, is recognized as an ancient Chinese medicine for malaria.

Respect for ancient wisdom is reflected in herbal medicine and phytopharmacy. The use of plant products to treat disease is well known in South American countries, China and India, where billions of dollars are spent on pharmacognosy research to identify and commercialize natural medicines.

The importance of medicinal plants should also be studied in other countries in order to fight against currently incurable and / or fatal diseases such as Alzheimer’s disease, HIV, chronic pain and malaria. Several natural drugs are currently being studied in clinical trials.

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Further reading